Platelet Factor 4 Proteins (PF4)

PF4 encodes a member of the CXC chemokine family. Additionally we are shipping Platelet Factor 4 Antibodies (163) and Platelet Factor 4 Kits (91) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PF4 5196 P02776
PF4 56744 Q9Z126
PF4 360918 P06765
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top Platelet Factor 4 Proteins at antibodies-online.com

Showing 10 out of 77 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated 100 μg Log in to see 10 to 12 Days
$635.93
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated 100 μg Log in to see 20 to 21 Days
$492.80
Details
HOST_Escherichia coli (E. coli) Human His tag 20 μg Log in to see 2 to 3 Days
$295.00
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated   10 μg Log in to see 10 to 12 Days
$135.88
Details
Yeast Wild boar His tag   1 mg Log in to see 60 to 71 Days
$2,143.17
Details
HOST_Escherichia coli (E. coli) Rat His tag,GST tag 100 μg Log in to see 15 to 18 Days
$560.00
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated   50 μg Log in to see 2 to 3 Days
$575.00
Details
HOST_Escherichia coli (E. coli) Mouse His tag 100 μg Log in to see 15 to 18 Days
$720.00
Details

PF4 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , , ,
, ,
Mouse (Murine)
,
Rat (Rattus) ,
,

More Proteins for Platelet Factor 4 (PF4) Interaction Partners

Human Platelet Factor 4 (PF4) interaction partners

  1. data support that increased levels of circulating CXCL4 may contribute to immune dysregulation through the modulation of dendritic cell differentiation

  2. Endometrial CXCL4 mRNA concentrations were significantly increased during menstruation. In women with heavy menstrual bleeding, CXCL4 was reduced in endothelial cells during the menstrual phase compared with women with normal menstrual bleeding. These data implicate CXCL4 in endometrial repair after menses.

  3. Two haplotype blocks, one upstream to the coding region of UGT2A1 (rs146712414, P = 9.1 x 10(-5); odds ratio [OR], 1.34; 95% confidence interval [CI], 1.16-1.56) and one downstream of the genes PF4/PPBP/CXCL5 (rs1595009, P = 1.3 x 10(-4); OR, 1.32; 95% CI, 1.15-1.52), were associated with AgP.

  4. These data demonstrate that the CXCR2 (show CXCR2 Proteins) network and CXCL4 play a role in the maintenance of normal HSC (show FUT1 Proteins)/HPC cell fates, including survival and self-renewal.

  5. The major aim of this review article was to evaluate the role of CXCL4 in hematological malignancies, promotion of HSC (show FUT1 Proteins) quiescence as well as BM niche cells.

  6. binding of PF4 to perlecan (show HSPG2 Proteins) was found to inhibit both FGF2 (show FGF2 Proteins) signaling and platelet activation

  7. CXCL4 plays an important role in pancreatic inflammation

  8. Data suggest that serum haptoglobin, fetuin-A, platelet factor-4, hs-CRP (high sensitive-C-reactive protein), SAP (serum amyloid P), AGP (alpha1-acid glycoprotein) levels of adolescents with metabolic syndrome are significantly higher than those of controls subjects.

  9. The hitherto unknown association of increased serum CXCL4 with features of microvascular impairment in primary Sjogren's syndrome, along with the negative association with features of lymphocytic response suggest clarifying the possible implication of this chemokine (show CCL1 Proteins) in primary Sjogren's syndrome pathogenesis in larger studies.

  10. serum concentration of CXCL4 was significantly increased in patients with Chronic Liver Allograft Dysfunction (CLAD); CXCL4 mRNA was significantly increased in subjects with CLAD versus individuals without CLAD

Mouse (Murine) Platelet Factor 4 (PF4) interaction partners

  1. These data demonstrate that the CXCR2 (show CXCR2 Proteins) network and CXCL4 play a role in the maintenance of normal HSC (show FUT1 Proteins)/HPC cell fates, including survival and self-renewal.

  2. Platelet-derived CXCL7 (show PPBP Proteins) and CXCL4 contribute to the pathogenesis of acute lung injury.

  3. CXCL4 plays an important role in pancreatic inflammation

  4. Platelet secretion of CXCL4 is Rac1-dependent and regulates neutrophil infiltration and tissue damage in septic lung damage

  5. PF4 has a complex intramedullary life cycle with important implications in megakaryopoiesis and hematopoietic stem cell replication not seen with other tested alpha granule proteins.

  6. Heparin enhances antigen uptake and activation of the initial steps in the cellular immune response to PF4-containing complexes.

  7. Data indicate that platelet factor 4 (PF4) is involved directly in liver innate immune response against ischaemia-reperfusion injury (IRI) by regulating Th17 cell differentiation.

  8. CXCL4 regulates hematopoietic stem cell cell cycle activity.

  9. Platelet factor 4 has a role in regulating Th17 differentiation and cardiac allograft rejection

  10. Histones regulate activated protein C (show PROC Proteins) formation in a manner similar to PF4 and suggest heparinoids may be benificial in sepsis.

Platelet Factor 4 (PF4) Protein Profile

Protein Summary

This gene encodes a member of the CXC chemokine family. This chemokine is released from the alpha granules of activated platelets in the form of a homotetramer which has high affinity for heparin and is involved in platelet aggregation. This protein is chemotactic for numerous other cell type and also functions as an inhibitor of hematopoiesis, angiogenesis and T-cell function.

Gene names and symbols associated with Platelet Factor 4 Proteins (PF4)

  • platelet factor 4 (PF4)
  • platelet factor 4 (Pf4)
  • Cxcl4 protein
  • PF-4 protein
  • Pf4a protein
  • RATPF4A protein
  • Scyb4 protein

Protein level used designations for Platelet Factor 4 Proteins (PF4)

platelet factor 4 (chemokine (C-X-C motif) ligand 4) , C-X-C motif chemokine 4 , chemokine (C-X-C motif) ligand 4 , iroplact , oncostatin-A , PF-4

GENE ID SPECIES
703451 Macaca mulatta
740477 Pan troglodytes
5196 Homo sapiens
56744 Mus musculus
360918 Rattus norvegicus
507790 Bos taurus
101104401 Ovis aries
Selected quality suppliers for Platelet Factor 4 Proteins (PF4)
Did you look for something else?