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The protein encoded by PECAM1 is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. Additionally we are shipping CD31 Kits (72) and CD31 Proteins (40) and many more products for this protein.
Showing 10 out of 1192 products:
Rat (Rattus) Monoclonal CD31 Primary Antibody for FACS - ABIN182012
Stevenson, McGlynn, Hodge, McLinden, George, Davies, Shiels: Isolation, characterization, and differentiation of thy1.1-sorted pancreatic adult progenitor cell populations. in Stem cells and development 2009
Show all 12 references for ABIN182012
Mouse (Murine) Monoclonal CD31 Primary Antibody for FACS, IHC (fro) - ABIN111979
Leenen, Melis, Slieker, Van Ewijk: Murine macrophage precursor characterization. II. Monoclonal antibodies against macrophage precursor antigens. in European journal of immunology 1990
Show all 8 references for ABIN111979
Human Monoclonal CD31 Primary Antibody for IHC (p) - ABIN1688318
Hatem, Labiod, Château-Joubert, de Plater, El Botty, Vacher, Bonin, Servely, Dieras, Bièche, Marangoni: Vandetanib as a potential new treatment for estrogen receptor-negative breast cancers. in International journal of cancer 2016
Show all 5 references for ABIN1688318
Rat (Rattus) Monoclonal CD31 Primary Antibody for EIA, FACS - ABIN120453
Flaris, Densmore, Molleston, Hickey et al.: Characterization of microglia and macrophages in the central nervous system of rats: definition of the differential expression of molecules using standard and novel monoclonal antibodies in normal ... in Glia 1993
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Human Polyclonal CD31 Primary Antibody for FACS, IHC (p) - ABIN391674
Simmons, Walker, Power, Pigott: Molecular cloning of CD31, a putative intercellular adhesion molecule closely related to carcinoembryonic antigen. in The Journal of experimental medicine 1990
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Human Monoclonal CD31 Primary Antibody for IHC (p) - ABIN1688711
Cañadas, Rojo, Taus, Arpí, Arumí-Uría, Pijuan, Menéndez, Zazo, Dómine, Salido, Mojal, García de Herreros, Rovira, Albanell, Arriola: Targeting epithelial-to-mesenchymal transition with Met inhibitors reverts chemoresistance in small cell lung cancer. in Clinical cancer research : an official journal of the American Association for Cancer Research 2014
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Rat (Rattus) Monoclonal CD31 Primary Antibody for FACS - ABIN320312
Male, Rahman, Linke, Zhao, Hickey: An interferon-inducible molecule on brain endothelium which controls lymphocyte adhesion mediated by integrins. in Immunology 1995
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Human Polyclonal CD31 Primary Antibody for EIA, WB - ABIN359628
Newman, Berndt, Gorski, White, Lyman, Paddock, Muller: PECAM-1 (CD31) cloning and relation to adhesion molecules of the immunoglobulin gene superfamily. in Science (New York, N.Y.) 1990
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Human Monoclonal CD31 Primary Antibody for IHC (p) - ABIN181867
Cabañas, Sanchez-Madrid, Bellon, Figdor, Te Velde, Fernandez, Acevedo, Bernabeu: Characterization of a novel myeloid antigen regulated during differentiation of monocytic cells. in European journal of immunology 1989
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Human Monoclonal CD31 Primary Antibody for FACS, IHC (fro) - ABIN111924
Soupene, Serikov, Kuypers: Characterization of an acyl-coenzyme A binding protein predominantly expressed in human primitive progenitor cells. in Journal of lipid research 2008
novel pathway for PECAM-1 regulation
PECAM-1 may not function as a major mechanoreceptor for activation of MAPK (show MAPK1 Antibodies) and AKT (show AKT1 Antibodies) in ECs and that there are likely to be other mechanoreceptors in ECs functioning to detect shear stress and trigger intercellular signals.
PECAM-1 and Fyn (show FYN Antibodies) are essential components of a PECAM-1-based mechanosensory complex in endothelial cells
PECAM-1 plays a role in the early pathogenesis of thrombotic meningoencephalitis.
We provide the first report that pro-angiogenic genes PECAM1, PTGS1 (show PTGS1 Antibodies), FGD5 (show FGD5 Antibodies), and MCAM (show MCAM Antibodies) may play a vital role in pathological dermal angiogenesis disorders of psoriasis.
The PECAM-1 functions as an adhesive stress-response protein to both maintain endothelial cell junctional integrity and speed restoration of the vascular permeability barrier following inflammatory or thrombotic challenge.
These studies indicate a role for PECAM-1 in enhancing the inhibitory functions of TGF-beta (show TGFB1 Antibodies) in T cells
PECAM1 plays an important role in the formation of tight junction complex.
The most significant associations were detected for PECAM1*V/V + DDAH1 (show DDAH1 Antibodies)*C (OR = 4.17 CI 1.56-11.15 Pperm = 0.005)
soluble CD38 (sCD38) in seminal plasma increases the capacitation of sperm via specific interactions between sCD38 and the CD31 (show HBA1 Antibodies) on the sperm.
expression levels of CD31/ PECAM1 are deregulated in human glioblastoma multiforme tissue specimens; correlation among CD31/PECAM1 and HIF-1alpha (show HIF1A Antibodies) and N-cadherin (show CDH2 Antibodies) and ADAM-10 (show ADAM10 Antibodies), two other markers of aggressiveness in the same tumors
Radiation-induced stress conditions induce a transient accumulation of granulocytes within the liver by down-regulation/absence of PECAM-1.
Suggest that CD31 (show HBA1 Antibodies) expression correlates with prognosis in gastrointestinal stromal tumors.
PECAM-1 125C/G polymorphism is associated with deep vein thrombosis.
PECAM1 acts upstream of Gab1 (show GAB1 Antibodies), promoting Gab1 (show GAB1 Antibodies)/Akt (show AKT1 Antibodies)/eNOS (show NOS3 Antibodies) phosphorylation and activation, thereby confers EC responsiveness to flow.
CD31 gene transfer is sufficient to recapitulate the cytoprotective mechanisms in CD31(-) pancreatic beta cells, which become resistant to immune-mediated rejection when grafted in fully allogeneic recipients
PECAM1+ melanoma cells form vascular channels
Data indicate that in lymphocyte specific 1 (show LSP1 Antibodies) protein (LSP1 (show LSP1 Antibodies))-deficient mice, PECAM-1 expression was reduced in endothelial cells, but not in neutrophils.
Nck (show NCK1 Antibodies) promoted oxidative stress-induced (show SQSTM1 Antibodies) activation of NF-kappaB (show NFKB1 Antibodies) by coupling the tyrosine phosphorylation of PECAM-1 (platelet endothelial cell adhesion molecule-1) to the activation of p21 (show D4S234E Antibodies)-activated kinase
PECAM-1 has a role in mediating the profibrotic and prometastasic environment caused by ethanol in endothelial cells
the T cell co-inhibitory receptor CD31 prevents the formation of functional T/B immunological synapses and that therapeutic strategies aimed at sustaining CD31 signaling will attenuate the development of autoimmune responses in vivo.
MMP-9 (show MMP9 Antibodies) activity disrupts vascular integrity at least partially through a PECAM-1 dependent mechanism and interferes with regeneration of steatotic livers after ischemia/reperfusion injury.
The protein encoded by this gene is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. The encoded protein is a member of the immunoglobulin superfamily and is likely involved in leukocyte migration, angiogenesis, and integrin activation.
platelet endothelial cell adhesion molecule
, CD31 antigen
, platelet/endothelial cell adhesion molecule (CD31 antigen)
, type I transmembrane endothelial adhesion molecule