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The protein encoded by PECAM1 is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. Additionally we are shipping CD31 Antibodies (1214) and CD31 Proteins (40) and many more products for this protein.
Showing 10 out of 69 products:
Mouse (Murine) CD31 ELISA Kit for Sandwich ELISA - ABIN921113
Chen, Jia, Ma, Wang, Teng: In vivo serial MR imaging of magnetically labeled endothelial progenitor cells homing to the endothelium injured artery in mice. in PLoS ONE 2011
Show all 6 references for ABIN921113
Human CD31 ELISA Kit for Sandwich ELISA - ABIN417327
Tu, Hu, Chen: Endothelial gene expression and molecular changes in response to radiosurgery in in vitro and in vivo models of cerebral arteriovenous malformations. in BioMed research international 2013
novel pathway for PECAM-1 regulation
PECAM-1 may not function as a major mechanoreceptor for activation of MAPK (show MAPK1 ELISA Kits) and AKT (show AKT1 ELISA Kits) in ECs and that there are likely to be other mechanoreceptors in ECs functioning to detect shear stress and trigger intercellular signals.
PECAM-1 and Fyn (show FYN ELISA Kits) are essential components of a PECAM-1-based mechanosensory complex in endothelial cells
PECAM-1 plays a role in the early pathogenesis of thrombotic meningoencephalitis.
We provide the first report that pro-angiogenic genes PECAM1, PTGS1 (show PTGS1 ELISA Kits), FGD5, and MCAM (show MCAM ELISA Kits) may play a vital role in pathological dermal angiogenesis disorders of psoriasis.
The PECAM-1 functions as an adhesive stress-response protein to both maintain endothelial cell junctional integrity and speed restoration of the vascular permeability barrier following inflammatory or thrombotic challenge.
These studies indicate a role for PECAM-1 in enhancing the inhibitory functions of TGF-beta (show TGFB1 ELISA Kits) in T cells
PECAM1 plays an important role in the formation of tight junction complex.
The most significant associations were detected for PECAM1*V/V + DDAH1 (show DDAH1 ELISA Kits)*C (OR = 4.17 CI 1.56-11.15 Pperm = 0.005)
soluble CD38 (sCD38) in seminal plasma increases the capacitation of sperm via specific interactions between sCD38 and the CD31 (show HBA1 ELISA Kits) on the sperm.
expression levels of CD31/ PECAM1 are deregulated in human glioblastoma multiforme tissue specimens; correlation among CD31/PECAM1 and HIF-1alpha (show HIF1A ELISA Kits) and N-cadherin (show CDH2 ELISA Kits) and ADAM-10 (show ADAM10 ELISA Kits), two other markers of aggressiveness in the same tumors
Radiation-induced stress conditions induce a transient accumulation of granulocytes within the liver by down-regulation/absence of PECAM-1.
Suggest that CD31 (show HBA1 ELISA Kits) expression correlates with prognosis in gastrointestinal stromal tumors.
PECAM-1 125C/G polymorphism is associated with deep vein thrombosis.
PECAM1 acts upstream of Gab1, promoting Gab1/Akt (show AKT1 ELISA Kits)/eNOS (show NOS3 ELISA Kits) phosphorylation and activation, thereby confers EC responsiveness to flow.
CD31 gene transfer is sufficient to recapitulate the cytoprotective mechanisms in CD31(-) pancreatic beta cells, which become resistant to immune-mediated rejection when grafted in fully allogeneic recipients
PECAM1+ melanoma cells form vascular channels
Data indicate that in lymphocyte specific 1 (show LSP1 ELISA Kits) protein (LSP1 (show LSP1 ELISA Kits))-deficient mice, PECAM-1 expression was reduced in endothelial cells, but not in neutrophils.
Nck (show NCK1 ELISA Kits) promoted oxidative stress-induced (show SQSTM1 ELISA Kits) activation of NF-kappaB (show NFKB1 ELISA Kits) by coupling the tyrosine phosphorylation of PECAM-1 (platelet endothelial cell adhesion molecule-1) to the activation of p21-activated kinase
PECAM-1 has a role in mediating the profibrotic and prometastasic environment caused by ethanol in endothelial cells
the T cell co-inhibitory receptor CD31 prevents the formation of functional T/B immunological synapses and that therapeutic strategies aimed at sustaining CD31 signaling will attenuate the development of autoimmune responses in vivo.
MMP-9 (show MMP9 ELISA Kits) activity disrupts vascular integrity at least partially through a PECAM-1 dependent mechanism and interferes with regeneration of steatotic livers after ischemia/reperfusion injury.
The protein encoded by this gene is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. The encoded protein is a member of the immunoglobulin superfamily and is likely involved in leukocyte migration, angiogenesis, and integrin activation.
platelet endothelial cell adhesion molecule
, CD31 antigen
, platelet/endothelial cell adhesion molecule (CD31 antigen)
, type I transmembrane endothelial adhesion molecule