You are viewing an incomplete version of our website. Please click to reload the website as full version.

Platelet/endothelial Cell Adhesion Molecule Proteins (PECAM1)

The protein encoded by PECAM1 is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. Additionally we are shipping CD31 Antibodies (914) and CD31 Kits (89) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PECAM1 5175 P16284
PECAM1 18613 Q08481
PECAM1 29583 Q3SWT0
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top CD31 Proteins at antibodies-online.com

Showing 10 out of 40 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Human Cells Human His tag 100 μg Log in to see 16 Days
$250.80
Details
HOST_Human Cells Mouse His tag 100 μg Log in to see 16 Days
$382.80
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 59 to 64 Days
$6,052.17
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 59 to 64 Days
$8,623.45
Details
HOST_HEK-293 Cells Human His tag 100 μg Log in to see 2 to 3 Days
$275.00
Details
HOST_HEK-293 Human Un-conjugated   50 μg Log in to see 2 to 3 Days
$346.50
Details
HOST_Escherichia coli (E. coli) Rat His tag,GST tag 100 μg Log in to see 11 to 13 Days
$721.60
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

PECAM1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , , , , ,
, , ,
Mouse (Murine) , , ,
,
Rat (Rattus) ,
,

Top referenced CD31 Proteins

  1. Human CD31 Protein expressed in Human Cells - ABIN2002172 : Newman, Berndt, Gorski, White, Lyman, Paddock, Muller: PECAM-1 (CD31) cloning and relation to adhesion molecules of the immunoglobulin gene superfamily. in Science (New York, N.Y.) 1990 (PubMed)
    Show all 5 references for ABIN2002172

  2. Mouse (Murine) CD31 Protein expressed in Human Cells - ABIN2007760 : Sun, Williams, Yan, Amin, Albelda, DeLisser et al.: Platelet endothelial cell adhesion molecule-1 (PECAM-1) homophilic adhesion is mediated by immunoglobulin-like domains 1 and 2 and depends on the cytoplasmic domain and the level of surface ... in The Journal of biological chemistry 1996 (PubMed)
    Show all 5 references for ABIN2007760

More Proteins for Platelet/endothelial Cell Adhesion Molecule (PECAM1) Interaction Partners

Cow (Bovine) Platelet/endothelial Cell Adhesion Molecule (PECAM1) interaction partners

  1. novel pathway for PECAM-1 regulation

  2. PECAM-1 may not function as a major mechanoreceptor for activation of MAPK (show MAPK1 Proteins) and AKT (show AKT1 Proteins) in ECs and that there are likely to be other mechanoreceptors in ECs functioning to detect shear stress and trigger intercellular signals.

  3. PECAM-1 and Fyn (show FYN Proteins) are essential components of a PECAM-1-based mechanosensory complex in endothelial cells

  4. PECAM-1 plays a role in the early pathogenesis of thrombotic meningoencephalitis.

Human Platelet/endothelial Cell Adhesion Molecule (PECAM1) interaction partners

  1. PECAM1 plays an important role in the formation of tight junction complex.

  2. The most significant associations were detected for PECAM1*V/V + DDAH1 (show DDAH1 Proteins)*C (OR = 4.17 CI 1.56-11.15 Pperm = 0.005)

  3. soluble CD38 (sCD38) in seminal plasma increases the capacitation of sperm via specific interactions between sCD38 and the CD31 (show HBA1 Proteins) on the sperm.

  4. expression levels of CD31/ PECAM1 are deregulated in human glioblastoma multiforme tissue specimens; correlation among CD31/PECAM1 and HIF-1alpha (show HIF1A Proteins) and N-cadherin (show CDH2 Proteins) and ADAM-10 (show ADAM10 Proteins), two other markers of aggressiveness in the same tumors

  5. Radiation-induced stress conditions induce a transient accumulation of granulocytes within the liver by down-regulation/absence of PECAM-1.

  6. Suggest that CD31 (show HBA1 Proteins) expression correlates with prognosis in gastrointestinal stromal tumors.

  7. PECAM-1 125C/G polymorphism is associated with deep vein thrombosis.

  8. Heterogeneity was found in the endothelial cells: their shape, the expression of adhesion molecules(ICAM-1 (show ICAM1 Proteins), VCAM-1 (show VCAM1 Proteins), and PECAM ), and the adhesion of lymphocytes and monocytes to them changed during the progression of the atherosclerotic process.

  9. PECAM1+ melanoma cells form vascular channels

  10. Low shear stress can induce inflammatory response via PECAM-1/PARP-1 (show PARP1 Proteins)/HMGB1 (show HMGB1 Proteins) pathway.

Mouse (Murine) Platelet/endothelial Cell Adhesion Molecule (PECAM1) interaction partners

  1. PECAM1 acts upstream of Gab1, promoting Gab1/Akt (show AKT1 Proteins)/eNOS (show NOS3 Proteins) phosphorylation and activation, thereby confers EC responsiveness to flow.

  2. Radiation-induced stress conditions induce a transient accumulation of granulocytes within the liver by down-regulation/absence of PECAM-1.

  3. CD31 gene transfer is sufficient to recapitulate the cytoprotective mechanisms in CD31(-) pancreatic beta cells, which become resistant to immune-mediated rejection when grafted in fully allogeneic recipients

  4. PECAM1+ melanoma cells form vascular channels

  5. Data indicate that in lymphocyte specific 1 (show LSP1 Proteins) protein (LSP1 (show LSP1 Proteins))-deficient mice, PECAM-1 expression was reduced in endothelial cells, but not in neutrophils.

  6. Nck (show NCK1 Proteins) promoted oxidative stress-induced (show SQSTM1 Proteins) activation of NF-kappaB (show NFKB1 Proteins) by coupling the tyrosine phosphorylation of PECAM-1 (platelet endothelial cell adhesion molecule-1) to the activation of p21-activated kinase

  7. PECAM-1 has a role in mediating the profibrotic and prometastasic environment caused by ethanol in endothelial cells

  8. the T cell co-inhibitory receptor CD31 prevents the formation of functional T/B immunological synapses and that therapeutic strategies aimed at sustaining CD31 signaling will attenuate the development of autoimmune responses in vivo.

  9. MMP-9 (show MMP9 Proteins) activity disrupts vascular integrity at least partially through a PECAM-1 dependent mechanism and interferes with regeneration of steatotic livers after ischemia/reperfusion injury.

  10. We have identified a single locus, at 35.8 Mb on murine chromosome 2, associated with PECAM-independent inflammation in the thioglycollate peritonitis (TGP (show TGM4 Proteins)) model. We suggest a name of Pitgp for this locus.

CD31 (PECAM1) Protein Profile

Protein Summary

The protein encoded by this gene is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. The encoded protein is a member of the immunoglobulin superfamily and is likely involved in leukocyte migration, angiogenesis, and integrin activation.

Gene names and symbols associated with PECAM1

  • platelet/endothelial cell adhesion molecule (LOC569386)
  • platelet/endothelial cell adhesion molecule (PECAM1)
  • platelet/endothelial cell adhesion molecule 1 (PECAM1)
  • platelet/endothelial cell adhesion molecule 1 (Pecam1)
  • C85791 protein
  • Cd31 protein
  • CD31/EndoCAM protein
  • endoCAM protein
  • GPIIA' protein
  • PECA1 protein
  • Pecam protein
  • PECAM-1 protein

Protein level used designations for PECAM1

platelet endothelial cell adhesion molecule , CD31 antigen , PECAM-1 , platelet/endothelial cell adhesion molecule (CD31 antigen) , PECAM-1/CD31 , type I transmembrane endothelial adhesion molecule

GENE ID SPECIES
569386 Danio rerio
282303 Bos taurus
5175 Homo sapiens
18613 Mus musculus
29583 Rattus norvegicus
396941 Sus scrofa
100734230 Cavia porcellus
610775 Canis lupus familiaris
771243 Gallus gallus
100303608 Ovis aries
Selected quality suppliers for CD31 Proteins (PECAM1)
Did you look for something else?