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Platelet/endothelial Cell Adhesion Molecule Proteins (PECAM1)

The protein encoded by PECAM1 is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. Additionally we are shipping CD31 Antibodies (1191) and CD31 Kits (69) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PECAM1 5175 P16284
PECAM1 18613 Q08481
PECAM1 29583 Q3SWT0
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Top CD31 Proteins at antibodies-online.com

Showing 10 out of 40 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Human Cells Human His tag 100 μg Log in to see 16 Days
$250.80
Details
HOST_Human Cells Mouse His tag 100 μg Log in to see 16 Days
$382.80
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 59 to 64 Days
$6,052.17
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 59 to 64 Days
$8,623.45
Details
HOST_HEK-293 Cells Human His tag Human CD31, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 98%. 100 μg Log in to see 2 to 3 Days
$275.00
Details
HOST_HEK-293 Human Un-conjugated   50 μg Log in to see 2 to 3 Days
$346.50
Details
HOST_Escherichia coli (E. coli) Rat His tag,GST tag 100 μg Log in to see 11 to 13 Days
$721.60
Details
HOST_Mammalian Cells Human His tag   10 μg Log in to see 5 Days
$127.05
Details

PECAM1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , , , , , ,
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Mouse (Murine) , , ,
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Rat (Rattus) ,
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Top referenced CD31 Proteins

  1. Human CD31 Protein expressed in Human Cells - ABIN2002172 : Newman, Berndt, Gorski, White, Lyman, Paddock, Muller: PECAM-1 (CD31) cloning and relation to adhesion molecules of the immunoglobulin gene superfamily. in Science (New York, N.Y.) 1990 (PubMed)
    Show all 5 references for ABIN2002172

  2. Mouse (Murine) CD31 Protein expressed in Human Cells - ABIN2007760 : Sun, Williams, Yan, Amin, Albelda, DeLisser et al.: Platelet endothelial cell adhesion molecule-1 (PECAM-1) homophilic adhesion is mediated by immunoglobulin-like domains 1 and 2 and depends on the cytoplasmic domain and the level of surface ... in The Journal of biological chemistry 1996 (PubMed)
    Show all 5 references for ABIN2007760

More Proteins for Platelet/endothelial Cell Adhesion Molecule (PECAM1) Interaction Partners

Cow (Bovine) Platelet/endothelial Cell Adhesion Molecule (PECAM1) interaction partners

  1. novel pathway for PECAM-1 regulation

  2. PECAM-1 may not function as a major mechanoreceptor for activation of MAPK (show MAPK1 Proteins) and AKT (show AKT1 Proteins) in ECs and that there are likely to be other mechanoreceptors in ECs functioning to detect shear stress and trigger intercellular signals.

  3. PECAM-1 and Fyn (show FYN Proteins) are essential components of a PECAM-1-based mechanosensory complex in endothelial cells

  4. PECAM-1 plays a role in the early pathogenesis of thrombotic meningoencephalitis.

Human Platelet/endothelial Cell Adhesion Molecule (PECAM1) interaction partners

  1. CD31 (show HBA1 Proteins) is expressed in mycosis fungoides (MF) skin biopsies, which provides new evidence for the role of angiogenesis in the progression of MF

  2. The Leu125Val polymorphism of PECAM-1 and the level of soluble PECAM-1 are not associated with diabetic nephropathy in Caucasians with type 2 diabetes mellitus.

  3. We provide the first report that pro-angiogenic genes PECAM1, PTGS1 (show PTGS1 Proteins), FGD5 (show FGD5 Proteins), and MCAM (show MCAM Proteins) may play a vital role in pathological dermal angiogenesis disorders of psoriasis.

  4. The PECAM-1 functions as an adhesive stress-response protein to both maintain endothelial cell junctional integrity and speed restoration of the vascular permeability barrier following inflammatory or thrombotic challenge.

  5. These studies indicate a role for PECAM-1 in enhancing the inhibitory functions of TGF-beta (show TGFB1 Proteins) in T cells

  6. PECAM1 plays an important role in the formation of tight junction complex.

  7. The most significant associations were detected for PECAM1*V/V + DDAH1 (show DDAH1 Proteins)*C (OR = 4.17 CI 1.56-11.15 Pperm = 0.005)

  8. soluble CD38 (sCD38) in seminal plasma increases the capacitation of sperm via specific interactions between sCD38 and the CD31 (show HBA1 Proteins) on the sperm.

  9. expression levels of CD31/ PECAM1 are deregulated in human glioblastoma multiforme tissue specimens; correlation among CD31/PECAM1 and HIF-1alpha (show HIF1A Proteins) and N-cadherin (show CDH2 Proteins) and ADAM-10 (show ADAM10 Proteins), two other markers of aggressiveness in the same tumors

  10. Radiation-induced stress conditions induce a transient accumulation of granulocytes within the liver by down-regulation/absence of PECAM-1.

Mouse (Murine) Platelet/endothelial Cell Adhesion Molecule (PECAM1) interaction partners

  1. These studies indicate a role for PECAM-1 in enhancing the inhibitory functions of TGF-beta (show TGFB1 Proteins) in T cells

  2. PECAM1 acts upstream of Gab1, promoting Gab1/Akt (show AKT1 Proteins)/eNOS (show NOS3 Proteins) phosphorylation and activation, thereby confers EC responsiveness to flow.

  3. Radiation-induced stress conditions induce a transient accumulation of granulocytes within the liver by down-regulation/absence of PECAM-1.

  4. CD31 gene transfer is sufficient to recapitulate the cytoprotective mechanisms in CD31(-) pancreatic beta cells, which become resistant to immune-mediated rejection when grafted in fully allogeneic recipients

  5. PECAM1+ melanoma cells form vascular channels

  6. Data indicate that in lymphocyte specific 1 (show LSP1 Proteins) protein (LSP1 (show LSP1 Proteins))-deficient mice, PECAM-1 expression was reduced in endothelial cells, but not in neutrophils.

  7. Nck (show NCK1 Proteins) promoted oxidative stress-induced (show SQSTM1 Proteins) activation of NF-kappaB (show NFKB1 Proteins) by coupling the tyrosine phosphorylation of PECAM-1 (platelet endothelial cell adhesion molecule-1) to the activation of p21-activated kinase

  8. PECAM-1 has a role in mediating the profibrotic and prometastasic environment caused by ethanol in endothelial cells

  9. the T cell co-inhibitory receptor CD31 prevents the formation of functional T/B immunological synapses and that therapeutic strategies aimed at sustaining CD31 signaling will attenuate the development of autoimmune responses in vivo.

  10. MMP-9 (show MMP9 Proteins) activity disrupts vascular integrity at least partially through a PECAM-1 dependent mechanism and interferes with regeneration of steatotic livers after ischemia/reperfusion injury.

CD31 (PECAM1) Protein Profile

Protein Summary

The protein encoded by this gene is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. The encoded protein is a member of the immunoglobulin superfamily and is likely involved in leukocyte migration, angiogenesis, and integrin activation.

Gene names and symbols associated with PECAM1

  • platelet/endothelial cell adhesion molecule (LOC569386)
  • platelet/endothelial cell adhesion molecule (PECAM1)
  • platelet/endothelial cell adhesion molecule 1 (PECAM1)
  • platelet/endothelial cell adhesion molecule 1 (Pecam1)
  • C85791 protein
  • Cd31 protein
  • CD31/EndoCAM protein
  • endoCAM protein
  • GPIIA' protein
  • PECA1 protein
  • Pecam protein
  • PECAM-1 protein

Protein level used designations for PECAM1

platelet endothelial cell adhesion molecule , CD31 antigen , PECAM-1 , platelet/endothelial cell adhesion molecule (CD31 antigen) , PECAM-1/CD31 , type I transmembrane endothelial adhesion molecule

GENE ID SPECIES
569386 Danio rerio
282303 Bos taurus
5175 Homo sapiens
18613 Mus musculus
29583 Rattus norvegicus
396941 Sus scrofa
100734230 Cavia porcellus
610775 Canis lupus familiaris
771243 Gallus gallus
100303608 Ovis aries
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