Platelet-Activating Factor Acetylhydrolase 2, 40kDa Proteins (PAFAH2)

PAFAH2 encodes platelet-activating factor acetylhydrolase isoform 2, a single-subunit intracellular enzyme that catalyzes the removal of the acetyl group at the SN-2 position of platelet-activating factor (identified as 1-O-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine). Additionally we are shipping Platelet-Activating Factor Acetylhydrolase 2, 40kDa Antibodies (40) and Platelet-Activating Factor Acetylhydrolase 2, 40kDa Kits (14) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PAFAH2 5051 Q99487
PAFAH2 313611 P83006
PAFAH2 100163 Q8VDG7
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Top Platelet-Activating Factor Acetylhydrolase 2, 40kDa Proteins at antibodies-online.com

Showing 7 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$405.71
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HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$785.40
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Yeast Rat His tag   1 mg Log in to see 60 to 71 Days
$3,076.33
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Yeast Cow His tag   1 mg Log in to see 60 to 71 Days
$3,081.83
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HOST_Escherichia coli (E. coli) Human T7 tag,His tag   100 μg Log in to see 15 to 18 Days
$698.00
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PAFAH2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, , ,
Rat (Rattus)

Mouse (Murine)

More Proteins for Platelet-Activating Factor Acetylhydrolase 2, 40kDa (PAFAH2) Interaction Partners

Mouse (Murine) Platelet-Activating Factor Acetylhydrolase 2, 40kDa (PAFAH2) interaction partners

  1. These results indicate that PAF-AH (show Lp-PLA2 Proteins) (II) is involved in the metabolism of esterified 8-isoprostaglandin F(2alpha) and protects tissue from oxidative stress-induced (show SQSTM1 Proteins) injury.

Human Platelet-Activating Factor Acetylhydrolase 2, 40kDa (PAFAH2) interaction partners

  1. Data show that the activity of plasma platelet activating factor acetylhydrolase (PAF-AH (show Lp-PLA2 Proteins)) increases in parallel with diabetic retinopathy (DR) severity.

  2. The oligomeric state of PAFAH (show PAFAH1B1 Proteins)-II drives functional protein trafficking. PAFAH (show PAFAH1B1 Proteins)-II localization to the membrane is critical for substrate acquisition and effective oxidative stress protection.

  3. presence of platelet-activating factor acetylhydrolase (show Lp-PLA2 Proteins) II in a restricted pattern in human skin; it is involved in protecting this organ against oxidative stress through the degradation of oxidatively modified bioactive phospholipids.

  4. Lp-PLA2 (show Lp-PLA2 Proteins) was higher in those with more extensive Coronary artery disease

  5. PAF-AH II exerts strong neuroprotective effects against ischemic injury: the neurological deficit scores, cerebral edema index, and relative infarction volume are all significantly lower in PAFAH2 transgenic mice than in wild-type mice.

  6. examines substrate specificity for intracellular and plasma PAF (show KIAA0101 Proteins)-AHs (show AHSG Proteins)

Platelet-Activating Factor Acetylhydrolase 2, 40kDa (PAFAH2) Protein Profile

Protein Summary

This gene encodes platelet-activating factor acetylhydrolase isoform 2, a single-subunit intracellular enzyme that catalyzes the removal of the acetyl group at the SN-2 position of platelet-activating factor (identified as 1-O-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine). However, this lipase exhibits a broader substrate specificity than simply platelet activating factor. Two other isoforms of intracellular platelet-activating factor acetylhydrolase exist, and both are multi-subunit enzymes. Additionally, there is a single-subunit serum isoform of this enzyme.

Gene names and symbols associated with PAFAH2

  • platelet-activating factor acetylhydrolase 2, 40kDa (PAFAH2)
  • platelet-activating factor acetylhydrolase 2 (Pafah2)
  • platelet-activating factor acetylhydrolase 2, 40kDa (pafah2)
  • 2310074E22Rik protein
  • AI507170 protein
  • hsd-pla2 protein
  • PAFAH2 protein

Protein level used designations for PAFAH2

SD-PLA2 , platelet-activating factor acetylhydrolase 2, cytoplasmic , serine-dependent phospholipase A2 , platelet-activating factor acetylhydrolase 2 40kDa , platelet-activating factor acetylhydrolase 2, 40kDa , platelet-activating factor acetylhydrolase 2, cytoplasmic-like

GENE ID SPECIES
5051 Homo sapiens
282299 Bos taurus
313611 Rattus norvegicus
444010 Xenopus laevis
456651 Pan troglodytes
478174 Canis lupus familiaris
769963 Gallus gallus
100011603 Monodelphis domestica
100057370 Equus caballus
100338757 Oryctolagus cuniculus
100379949 Xenopus (Silurana) tropicalis
100402368 Callithrix jacchus
100435347 Pongo abelii
100482313 Ailuropoda melanoleuca
100597461 Nomascus leucogenys
100163 Mus musculus
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