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Major protein kinase C substrate of platelets.. Additionally we are shipping Pleckstrin Antibodies (76) and Pleckstrin Proteins (8) and many more products for this protein.
These findings reveal a novel role of the PLD1-pleckstrin homology domain as a positive regulator of endocytosis and provide a link between PLD1 and HIF-1alpha (show HIF1A ELISA Kits) in the EGFR (show EGFR ELISA Kits) endocytosis pathway.
crystallization and preliminary X-ray diffraction analysis of the first 2 domains of pleckstrin (NPHDEP); work demonstrates that NPHDEP behaves as a monomer in solution and suggests that all 3 pleckstrin domains contribute to the dimerization interface
Here they show that the PH domain from Bcr-Abl (show ABL1 ELISA Kits) binds a number of proteins involved in vital cellular processes in leukemogenesis.
A pleckstrin homology domain located in G protein-coupled receptor kinase-2 (GRK2 (show ADRBK1 ELISA Kits)) residue 548 to 660 plays a significant role in mediating interaction between protein kinase C beta 1 (show PRKCB ELISA Kits) and GRK2 (show ADRBK1 ELISA Kits).
The human pleckstrin-1 solution nuclear magnetic resonance structure of the C-terminal pleckstrin homology domain was reported.
Proteins beta3 integrin (show ITGB3 ELISA Kits), Vav3 (show VAV3 ELISA Kits), Plekhm1 (show PLEKHM1 ELISA Kits), and Src (show SRC ELISA Kits), implicated in attachment defects, had normal exon sequences in a new type of osteopetrosis (show CSF1 ELISA Kits).
Idirect associations between plek and actin through 17 beta-hydroxysteroid dehydrogenase 4 (show HSD17B4 ELISA Kits), alpha-actinin (show ACTN1 ELISA Kits), moesin (show MSN ELISA Kits), radixin (show RDX ELISA Kits) and factor XIIIA (show F13A1 ELISA Kits), is proposed.
Targeting of the pleckstrin homology domain of AKT (show AKT1 ELISA Kits) was studied in cancer treatment in mouse models.
pleckstrin regulates the fusion of granules to the cell membrane and is an essential component of PKC-mediated exocytosis in platelets
Major protein kinase C substrate of platelets.
, platelet 47 kDa protein