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Pleckstrin Homology-Like Domain, Family A, Member 1 Proteins (PHLDA1)

PHLDA1 encodes an evolutionarily conserved proline-histidine rich nuclear protein. Additionally we are shipping PHLDA1 Antibodies (48) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PHLDA1 22822 Q8WV24
PHLDA1 21664 Q62392
PHLDA1 29380  
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Top PHLDA1 Proteins at antibodies-online.com

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,129.50
Details

PHLDA1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

Rat (Rattus)

More Proteins for Pleckstrin Homology-Like Domain, Family A, Member 1 (PHLDA1) Interaction Partners

Human Pleckstrin Homology-Like Domain, Family A, Member 1 (PHLDA1) interaction partners

  1. Suggest decreased expression of PHLDA1 may play an important role in tumor progression, and may become a new adjunct biomarker in the prognosis in gastric adenocarcinoma.

  2. Data suggest that high PHLDA1 expression is controlled through an ER-NFkappaB (show NFKB1 Proteins)-miR (show MLXIP Proteins)-181 regulatory axis and may contribute to a poor clinical outcome in patients with ER+ breast tumors by enhancing stem-like properties in these tumors.

  3. PHLDA1 expression is a useful addition in differentiating trichoblastoma and basal cell carcinoma.

  4. A role for PHLDA1 as an apoptosis suppressor in oral cancer cells.

  5. Data show that downregulation of aurora A kinase (show AURKA Proteins) by the therapeutic antibody is associated with decreased levels of MYCN (show MYCN Proteins) protein in cytoplasm, and induced expression of PHLDA1 and P53 (show TP53 Proteins) proteins.

  6. The follicular stem cell marker PHLDA1 (TDAG51) indicates that most basaloid tumors in nevus sebaceus are basal cell carcinomas and not trichoblastomas.

  7. PHLDA1 differentiates between desmoplastic trichoepithelioma and morpheaform basal cell carcinoma but shows variable staining in microcystic adnexal carcinoma.

  8. the release of Ca(2 (show CA2 Proteins)+) from endoplasmic reticulum stores mediates epithelial-to-mesenchymal transition in human proximal tubular epithelium via the induction of TDAG51

  9. crucial negative regulator and effector of Aurora A kinase (show AURKA Proteins) in breast cancer

  10. PHLDA1 expression marks the putative epithelial stem cells, downregulates ITGA2 (show ITGA2 Proteins) and ITGA6 (show ITGA6 Proteins), and contributes to intestinal tumorigenesis

Mouse (Murine) Pleckstrin Homology-Like Domain, Family A, Member 1 (PHLDA1) interaction partners

  1. TDAG51 has a protective role in oxidative stress-induced (show SQSTM1 Proteins) cell death in mouse embryonic fibroblasts.

  2. Our results suggest that the balance between the cell survival and death signals mediated by HSP70 (show HSP70 Proteins) and TDAG51, respectively, may be disturbed by the altered expression of HSF1 (show HSF1 Proteins) during the progression of disease in this amyotropic lateral sclerosis model.

  3. TDAG51 is involved in energy homeostasis at least in part by regulating lipogenesis in liver and white adipose tissue.

  4. PHLDA1 expression marks the putative epithelial stem cells, downregulates ITGA2 (show ITGA2 Proteins) and ITGA6 (show ITGA6 Proteins), and contributes to intestinal tumorigenesis

  5. TDAG51 is induced by homocysteine, promotes detachment-mediated PCD, and contributes to the development of atherosclerosis observed in hyperhomocysteinemia

PHLDA1 Protein Profile

Protein Summary

This gene encodes an evolutionarily conserved proline-histidine rich nuclear protein. The encoded protein may play an important role in the anti-apoptotic effects of insulin-like growth factor-1.

Gene names and symbols associated with PHLDA1

  • pleckstrin homology-like domain, family A, member 1 (PHLDA1)
  • pleckstrin homology-like domain, family A, member 1 (Phlda1)
  • pleckstrin homology-like domain, family A, member 1 (phlda1)
  • DT1P1B11 protein
  • PHRIP protein
  • Tdag protein
  • TDAG51 protein

Protein level used designations for PHLDA1

PQ-rich protein , PQR protein , T-cell death-associated gene 51 protein , apoptosis-associated nuclear protein , pleckstrin homology-like domain family A member 1 , proline- and glutamine-rich protein , proline- and histidine-rich protein , proline-histidine rich protein , T-cell death associated

GENE ID SPECIES
22822 Homo sapiens
21664 Mus musculus
29380 Rattus norvegicus
540135 Bos taurus
100036927 Xenopus laevis
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