anti-Pleckstrin Homology-Like Domain, Family A, Member 1 (PHLDA1) Antibodies

PHLDA1 encodes an evolutionarily conserved proline-histidine rich nuclear protein. Additionally we are shipping PHLDA1 Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PHLDA1 22822 Q8WV24
PHLDA1 21664 Q62392
PHLDA1 29380  
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Top anti-PHLDA1 Antibodies at antibodies-online.com

Showing 10 out of 48 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-PHLDA1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: Human Placenta 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-PHLDA1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:62500 Positive Control: Human Placenta 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 16 Days
$175.80
Details
Cow Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Cow Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 7 to 9 Days
$478.50
Details
Human Rabbit Un-conjugated WB PHLDA1 Antibody (N-term) western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the PHLDA1 antibody detected the PHLDA1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded mouse pancreas labeled with Anti-PHLDA1/TDAG51 Polyclonal Antibody, Unconjugated (ABIN685492) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$295.90
Details
Human Rabbit Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Un-conjugated IF, ELISA, WB Detection limit for recombinant GST tagged PHLDA1 is 0.3 ng/ml as a capture antibody. Immunofluorescence of monoclonal antibody to PHLDA1 on HeLa cell. [antibody concentration 10 ug/ml] 100 μg Log in to see 11 to 12 Days
$430.00
Details

PHLDA1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , ,
,
,
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Mouse (Murine)


Rat (Rattus)


Top referenced anti-PHLDA1 Antibodies

  1. Cow (Bovine) Polyclonal PHLDA1 Primary Antibody for WB - ABIN2785898 : Tsuda, Davis, Argani, Shukla, McGill, Nagai, Saito, Laé, Fisher, Ladanyi: TFE3 fusions activate MET signaling by transcriptional up-regulation, defining another class of tumors as candidates for therapeutic MET inhibition. in Cancer research 2007 (PubMed)
    Show all 2 Pubmed References

  2. Cow (Bovine) Polyclonal PHLDA1 Primary Antibody for WB - ABIN2785897 : Nagai, Fregnani, Netto, Brentani, Soares: Down-regulation of PHLDA1 gene expression is associated with breast cancer progression. in Breast cancer research and treatment 2007 (PubMed)
    Show all 2 Pubmed References

More Antibodies against PHLDA1 Interaction Partners

Human Pleckstrin Homology-Like Domain, Family A, Member 1 (PHLDA1) interaction partners

  1. Our study negatively correlates expression of PHLDA1 and Aurora A (show AURKA Antibodies) in IMR-32 cells and sheds new light on functions of PHLDA1 in the neuroblastoma (show ARHGEF16 Antibodies) tumor cells, suggesting its role as a pro-apoptotic protein

  2. Suggest decreased expression of PHLDA1 may play an important role in tumor progression, and may become a new adjunct biomarker in the prognosis in gastric adenocarcinoma.

  3. Data suggest that high PHLDA1 expression is controlled through an ER-NFkappaB (show NFKB1 Antibodies)-miR (show MLXIP Antibodies)-181 regulatory axis and may contribute to a poor clinical outcome in patients with ER+ breast tumors by enhancing stem-like properties in these tumors.

  4. PHLDA1 expression is a useful addition in differentiating trichoblastoma and basal cell carcinoma.

  5. A role for PHLDA1 as an apoptosis suppressor in oral cancer cells.

  6. Data show that downregulation of aurora A kinase (show AURKA Antibodies) by the therapeutic antibody is associated with decreased levels of MYCN (show MYCN Antibodies) protein in cytoplasm, and induced expression of PHLDA1 and P53 (show TP53 Antibodies) proteins.

  7. The follicular stem cell marker PHLDA1 (TDAG51) indicates that most basaloid tumors in nevus sebaceus are basal cell carcinomas and not trichoblastomas.

  8. PHLDA1 differentiates between desmoplastic trichoepithelioma and morpheaform basal cell carcinoma but shows variable staining in microcystic adnexal carcinoma.

  9. the release of Ca(2 (show CA2 Antibodies)+) from endoplasmic reticulum stores mediates epithelial-to-mesenchymal transition in human proximal tubular epithelium via the induction of TDAG51

  10. crucial negative regulator and effector of Aurora A kinase (show AURKA Antibodies) in breast cancer

Mouse (Murine) Pleckstrin Homology-Like Domain, Family A, Member 1 (PHLDA1) interaction partners

  1. PHLDA1 plays a critical role in the development of progressive lung contusion and subsequent inflammation.

  2. These findings suggested that TDAG51 up-regulation is a dependent event during LPS (show TLR4 Antibodies)-mediated proliferation and cell cycle progression, and which increase our understanding of the interaction mechanism between LPS (show TLR4 Antibodies) and macrophages.

  3. The JAK2 (show JAK2 Antibodies)-ERK1/2 (show MAPK1/3 Antibodies)-STAT3 (show STAT3 Antibodies) pathway is an important signaling pathway for regulation of PHLDA1 expression.

  4. TDAG51 has a protective role in oxidative stress-induced (show SQSTM1 Antibodies) cell death in mouse embryonic fibroblasts.

  5. Our results suggest that the balance between the cell survival and death signals mediated by HSP70 (show HSP70 Antibodies) and TDAG51, respectively, may be disturbed by the altered expression of HSF1 (show HSF1 Antibodies) during the progression of disease in this amyotropic lateral sclerosis model.

  6. TDAG51 is involved in energy homeostasis at least in part by regulating lipogenesis in liver and white adipose tissue.

  7. PHLDA1 expression marks the putative epithelial stem cells, downregulates ITGA2 (show ITGA2 Antibodies) and ITGA6 (show ITGA6 Antibodies), and contributes to intestinal tumorigenesis

  8. TDAG51 is induced by homocysteine, promotes detachment-mediated PCD (show PCBD1 Antibodies), and contributes to the development of atherosclerosis observed in hyperhomocysteinemia

PHLDA1 Antigen Profile

Protein Summary

This gene encodes an evolutionarily conserved proline-histidine rich nuclear protein. The encoded protein may play an important role in the anti-apoptotic effects of insulin-like growth factor-1.

Gene names and symbols associated with PHLDA1

  • pleckstrin homology like domain family A member 1 (PHLDA1) antibody
  • pleckstrin homology like domain, family A, member 1 (Phlda1) antibody
  • pleckstrin homology-like domain, family A, member 1 (Phlda1) antibody
  • pleckstrin homology-like domain, family A, member 1 L homeolog (phlda1.L) antibody
  • DT1P1B11 antibody
  • PHRIP antibody
  • Tdag antibody
  • TDAG51 antibody

Protein level used designations for PHLDA1

PQ-rich protein , PQR protein , T-cell death-associated gene 51 protein , apoptosis-associated nuclear protein , pleckstrin homology-like domain family A member 1 , proline- and glutamine-rich protein , proline- and histidine-rich protein , proline-histidine rich protein , T-cell death associated

GENE ID SPECIES
22822 Homo sapiens
21664 Mus musculus
29380 Rattus norvegicus
540135 Bos taurus
100036927 Xenopus laevis
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