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Pleiomorphic adenoma gene-like 2 is a zinc-finger protein that recognizes DNA and/or RNA. Additionally we are shipping PLAGL2 Antibodies (11) and PLAGL2 Proteins (3) and many more products for this protein.
PLAGL2 expression induces lamellipodia formation and disruption of stress fiber formation.
PLAGL2 regulate cell cycle and apoptosis via activation of the p53 (show TP53 ELISA Kits) family member, p73 (show TP73 ELISA Kits), in human promonocytic U937 cells.
Transcriptome analysis revealed that these differentiation-suppressive activities are attributable in part to PLAGL2 modulation of Wnt (show WNT2 ELISA Kits)/beta-catenin (show CTNNB1 ELISA Kits) signaling
The data identify PC2 (show KRT6B ELISA Kits) as a novel PLAGL2-binding protein and important mediator of PLAGL2 transactivation.
PLAGL2 may modulate SP-C (show SFTPC ELISA Kits) expression during lung development.
Plag1 (show PLAG1 ELISA Kits) and Plagl2 are novel leukemia oncogenes that act by expanding hematopoietic progenitors expressing CbF beta (show CBFB ELISA Kits)-SMMHC (show MYH11 ELISA Kits).
These data clearly identify PLAGL2 as a novel regulator of NCF2/p67phox (show NCF2 ELISA Kits) gene expression as well as NADPH oxidase (show NOX1 ELISA Kits) activity and contribute to a greater understanding of the transcriptional regulation of NCF2 (show NCF2 ELISA Kits).
Coexpression of Tip60 (show KAT5 ELISA Kits) and PLAGL2 completely abolishes the sumoylation of PLAGL2.
Nuclear PLAGL2 occupied and transactivated the endogenous SP-C (show SFTPC ELISA Kits) promoter in hypoxic lung cells.These results further suggest that PLAGL2 is an oxidative stress responding regulator in lung cells.
This study thus uncovers a novel function of PLAGL2 as an oncoprotein through regulating the stability of Pirh2 (show RCHY1 ELISA Kits).
induces the expression of a proapoptotic protein Nip3, leading to cellular apoptosis.
PlagL2 regulates important aspects of dietary lipid absorption, and the PlagL2(-/-) animal model has implications for the amelioration of obesity and the metabolic syndrome.
Increased cell injury and/or death could be caused directly by the upregulation of bNip3 (show BNIP3 ELISA Kits), a preapoptotic molecule that dimerizes with Bcl-2 (show BCL2 ELISA Kits), or indirectly by the aberrant expression of SP-C (show SFTPC ELISA Kits)-induced endoplasmic reticulum stress in epithelial cells.
Pleiomorphic adenoma gene-like 2 is a zinc-finger protein that recognizes DNA and/or RNA.
zinc finger protein PLAGL2
, pleiomorphic adenoma gene-like 2
, zinc finger protein PLAGL2-like
, C2H2-type zinc finger protein
, pleiomorphic adenoma-like protein 2
, pleomorphic adenoma gene like 2