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PLRG1 encodes a core component of the cell division cycle 5-like (CDC5L) complex. Additionally we are shipping Pleiotropic Regulator 1 (PRL1 Homolog, Arabidopsis) Antibodies (64) and many more products for this protein.
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PLRG1 is a critical nuclear regulator of p53 (show TP53 Proteins)-dependent cell cycle progression and apoptosis during both embryonic development and adult tissue homeostasis.
Study includes the isolation of a cDNA encoding the human PRL1 homolog.
A central region in hnRNP-M (show HNRNPM Proteins) is required for interaction with CDC5L (show CDC5L Proteins)/PLRG1.
the interaction between CDC5L (show CDC5L Proteins) and PLRG1 is essential for pre-mRNA splicing
This gene encodes a core component of the cell division cycle 5-like (CDC5L) complex. The CDC5L complex is part of the spliceosome and is required for pre-mRNA splicing. The encoded protein plays a critical role in alternative splice site selection. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
pleiotropic regulator 1
, pleiotropic regulator 1 (PRL1 homolog, Arabidopsis)
, transport and golgi organization 4 homolog
, pleiotropic regulator 1 homolog