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Plexin B1 Proteins (PLXNB1)

Receptor for SEMA4D. Additionally we are shipping Plexin B1 Antibodies (49) and Plexin B1 Kits (4) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PLXNB1 235611 Q8CJH3
Rat PLXNB1 PLXNB1 316009  
PLXNB1 5364 O43157
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Top Plexin B1 Proteins at

Showing 4 out of 10 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific pu... 1 mg Log in to see 29 to 34 Days
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific pu... 1 mg Log in to see 29 to 34 Days
HOST_Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 11 to 13 Days
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 9 to 19 Days

PLXNB1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)


More Proteins for Plexin B1 (PLXNB1) Interaction Partners

Mouse (Murine) Plexin B1 (PLXNB1) interaction partners

  1. Deletion of plexin-B1, the high affinity receptor for semaphorin 4D (show SEMA4D Proteins), significantly (one-way ANOVA; p < 0.001) reduced thrombus weight (- 40%) in oxidative venous thrombosis.

  2. Sema (show SEMA3B Proteins) 4D/CD100 (show SEMA4D Proteins) is not only a ligand for plexin B1 but also a direct signaling receptor in mediating Sema (show SEMA3B Proteins) 4D/CD100 (show SEMA4D Proteins)-plexin B's biological functions.

  3. In Erb (show ERBB2 Proteins)B-2-overexpressing murine breast cancer, ablation of Plexin-B1 genes strongly reduced metastases. Plexin-B1 has no effect on tumorigenesis o (show ERBB2 Proteins)r tumor growth but is require (show RHOA Proteins)d for m (show RHOC Proteins)etastasis of ErbB-2-dependent breast cancers in vivo.

  4. Semaphorin 4D (show SEMA4D Proteins)-induced nitric oxide synthase (iNOS (show NOS2 Proteins)) and nitric oxide (NO) production are mediated through plexin-B1.

  5. a lack of plexin-B1 did not impact on cortical development in vivo

  6. LARG (show ARHGEF12 Proteins) plays a critical role in plexin-B1 signaling to stimulate Rho activation and cytoskeletal reorganization.

  7. binding of Sema (show SEMA3B Proteins) 4D to Plexin B1 stimulates the tyrosine kinase (show TYRO3 Proteins) activity of Met

  8. Results suggest that plexin-A1 (show PLXNA1 Proteins) and B1 interact in the adult brain and transduce semaphorin 3A (show SEMA3A Proteins) signaling in cooperation.

  9. The mechanism of semaphorin D (show SEMA3A Proteins) in the activation of the MAPK (show MAPK1 Proteins) pathway via plexin-B1 is reported.

  10. A possible role for plexin-B1 in ovarian follicle growth and steroidogenesis, most likely via the granulosa cells, is suggested.

Human Plexin B1 (PLXNB1) interaction partners

  1. results show that Sema4D (show SEMA4D Proteins)/plexin-B1 signaling promotes the translocation of androgen receptor (show AR Proteins) to the nucleus and thereby enhances AR transcriptional activity

  2. Plexin-B1 induces cutaneous squamous cell carcinoma cell proliferation, migration, and invasion by interacting with Sema4D (show SEMA4D Proteins). Plexin-B1 might serve as a useful biomarker and/or as a novel therapeutic target for cSCC (show CYP11A1 Proteins).

  3. Results show that decreased expression of Sema4D (show SEMA4D Proteins), plexin-B1 and -B2 was associated with local recurrence and poor prognosis of breast neoplasm.

  4. Dysregulation of the vascular endothelial growth factor and semaphorin ligand-receptor families in prostate cancer metastasis

  5. Blocking of CD100 (show SEMA4D Proteins), plexin B1 and/or B2 in adhesion experiments have shown that both CD100 (show SEMA4D Proteins) and plexins act as adhesion molecules involved in monocyte-endothelial cell binding.

  6. The Semaphorin 4D (show SEMA4D Proteins)-Plexin-B1-RhoA (show RHOA Proteins) signaling axis recruits pericytes and regulates vascular permeability through endothelial production of PDGF-B (show PDGFB Proteins) and ANGPTL4 (show ANGPTL4 Proteins).

  7. Activation of endogenous plexin-B1 enhances cell migration and tumor invasiveness in prostate cancer cells.

  8. Data indicate that Rnd1 (show RND1 Proteins) efficiently displaces Rac1 from its complex with Plexin-B1 but not vice versa.

  9. ErbB-2 (show ERBB2 Proteins) overexpression in human breast & ovarian cancer cell lines leads to phosphorylation & activation of Plexin-B1. This was required for ErbB-2 (show ERBB2 Proteins)-dependent activation of RhoA (show RHOA Proteins) & RhoC (show RHOC Proteins) & promoted invasive behavior.

  10. PlexinB1 mutations block plexinB1-mediated signalling pathways that inhibit cell motility.

Plexin B1 (PLXNB1) Protein Profile

Protein Summary

Receptor for SEMA4D. Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration.

Gene names and symbols associated with Plexin B1 Proteins (PLXNB1)

  • plexin B1 (PLXNB1)
  • plexin b1a (plxnb1a)
  • plexin B1 (Plxnb1)
  • 2900002G15Rik protein
  • AU042020 protein
  • im:7054247 protein
  • mKIAA0407 protein
  • PLEXIN-B1 protein
  • PLXN5 protein
  • SEP protein
  • si:ch211-220i18.5 protein
  • wu:fb83a09 protein

Protein level used designations for Plexin B1 Proteins (PLXNB1)

plexin B1 , plexin b1 , plexin-B1-like , plexin-B1 , plexin 5 , semaphorin receptor SEP

416046 Gallus gallus
460344 Pan troglodytes
561012 Danio rerio
709802 Macaca mulatta
100023271 Monodelphis domestica
100053891 Equus caballus
100078327 Ornithorhynchus anatinus
100342042 Oryctolagus cuniculus
100479690 Ailuropoda melanoleuca
100589890 Nomascus leucogenys
235611 Mus musculus
316009 Rattus norvegicus
5364 Homo sapiens
476636 Canis lupus familiaris
100522643 Sus scrofa
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