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Plexin B2 Proteins (PLXNB2)

Members of the B class of plexins, such as PLXNB2 are transmembrane receptors that participate in axon guidance and cell migration in response to semaphorins (Perrot et al. Additionally we are shipping Plexin B2 Antibodies (34) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PLXNB2 23654 O15031
PLXNB2 140570 B2RXS4
Rat PLXNB2 PLXNB2 315217  
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Top Plexin B2 Proteins at antibodies-online.com

Showing 3 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

PLXNB2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Plexin B2 (PLXNB2) Interaction Partners

Human Plexin B2 (PLXNB2) interaction partners

  1. Results show that decreased expression of Sema4D (show SEMA4D Proteins), plexin-B1 (show PLXNB1 Proteins) and -B2 was associated with local recurrence and poor prognosis of breast neoplasm.

  2. Two related guanine nucleotide exchange factors (GEFs), PDZ-RhoGEF (show ARHGEF11 Proteins) and leukemia-associated RhoGEF (LARG (show ARHGEF12 Proteins)), use their PDZ domains to bind class B plexins and play critical roles in signaling.

  3. Plexin-B2 promotes glioma invasion and vascularization

  4. Blocking of CD100 (show SEMA4D Proteins), plexin B1 (show PLXNB1 Proteins) and/or B2 in adhesion experiments have shown that both CD100 (show SEMA4D Proteins) and plexins act as adhesion molecules involved in monocyte-endothelial cell binding.

  5. In endometrial luminal epithelium, cadherin 6 (show CDH6 Proteins), desmoglein 2 (show DSG2 Proteins) and plexin b2 were surprisingly found in the apical as well as the lateral membrane domain; their knock-down compromised epithelial integrity.

  6. High PLEXIN B2 expression is associated with high-grade gliomas.

  7. Plexin B2 associates directly with two members of a recently identified family of Dbl (show MCF2 Proteins) homology/pleckstrin (show PLEK Proteins) homology containing guanine nucleotide exchange factors for Rho, PDZ-RhoGEF (show ARHGEF11 Proteins), and Leukemia-associated Rho GEF (show SLC2A4RG Proteins) (LARG (show ARHGEF12 Proteins)).

Mouse (Murine) Plexin B2 (PLXNB2) interaction partners

  1. During kidney morphogenesis and repair, renal tubular epithelial cells lacking the transmembrane receptor Plexin-B2 or its semaphorin ligands fail to correctly orient the mitotic spindle

  2. Data show that the Plexin B2 receptor interacts physically and functionally with Rnd3 (show RND3 Proteins) and stimulates RhoA (show RHOA Proteins) activity in migrating cortical neurons.

  3. In contrast to the GAP domain mutants, Plexin-B2 transgenic mice defective in Rho guanine nucleotide exchange factor binding are viable and fertile but exhibit abnormal development of the liver vasculature

  4. these results show that Plexin-B2 plays a role in postnatal neurogenesis and in the migration of subventricular zone-derived neuroblasts

  5. Data an association between Plexin-B2 and Plexin-D1 (show PLXND1 Proteins) with the negative regulation of IL-12 (show IL12A Proteins)/IL-23p40 in DCs.

  6. In vitro blocking of plexin B2 or CD100 (show SEMA4D Proteins) inhibited gamma-delta T cell activation.

  7. Data show that Plexin-B2 functions in macrophages as a negative regulator of the GTPases Rac (show AKT1 Proteins) and Cdc42 (show CDC42 Proteins) and as a negative regulator of basal cell motility and wound healing.

  8. deletion of Plexin B2 (Plxnb2), a semaphorin receptor that is expressed both in the pretubular aggregates and the ureteric epithelium in the developing kidney, results in renal hypoplasia and occasional double ureters

  9. We have identified here Sema4C (show SEMA4C Proteins) and Sema4G (show SEMA4G Proteins) as candidate ligands for Plexin-B2

  10. Plexin-B2 and Sema4C (show SEMA4C Proteins) are potential regulators of the vascular and endocrine system.

Plexin B2 (PLXNB2) Protein Profile

Protein Summary

Members of the B class of plexins, such as PLXNB2 are transmembrane receptors that participate in axon guidance and cell migration in response to semaphorins (Perrot et al. (2002)

Gene names and symbols associated with Plexin B2 Proteins (PLXNB2)

  • plexin B2 (PLXNB2)
  • plexin B2 (plxnb2)
  • plexin B2 (Plxnb2)
  • 1110007H23Rik protein
  • Debt protein
  • dJ402G11.3 protein
  • mKIAA0315 protein
  • MM1 protein
  • Nbla00445 protein
  • PLEXB2 protein
  • PLXNB2 protein

Protein level used designations for Plexin B2 Proteins (PLXNB2)

plexin B2 , plexin-B2 , plexin-B2-like , differentially expressed in brain tumors

GENE ID SPECIES
425938 Gallus gallus
494999 Xenopus laevis
508175 Bos taurus
550076 Xenopus (Silurana) tropicalis
720646 Macaca mulatta
100011009 Monodelphis domestica
100056317 Equus caballus
100172633 Pongo abelii
100474699 Ailuropoda melanoleuca
100566684 Anolis carolinensis
23654 Homo sapiens
140570 Mus musculus
315217 Rattus norvegicus
474459 Canis lupus familiaris
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