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Podoplanin Proteins (PDPN)

PDPN encodes a type-I integral membrane glycoprotein with diverse distribution in human tissues. Additionally we are shipping Podoplanin Antibodies (386) and Podoplanin Kits (44) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PDPN 10630 Q86YL7
PDPN 14726 Q62011
PDPN 54320 Q64294
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Top Podoplanin Proteins at antibodies-online.com

Showing 10 out of 30 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_HEK-293 Mouse Fc Tag 100 μg Log in to see 10 to 12 Days
$587.01
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$319.00
Details
HOST_Human Cells Human His tag,Fc Tag 100 μg Log in to see 16 Days
$382.80
Details
HOST_Human Cells Mouse His tag,Fc Tag 100 μg Log in to see 16 Days
$382.80
Details
HOST_Baculovirus infected Insect Cells Mouse His tag 100 μg Log in to see 16 Days
$382.80
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

PDPN Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , , ,
, , , ,
Mouse (Murine) , , , ,
, , ,
Rat (Rattus) , ,
,

Top referenced Podoplanin Proteins

  1. Mouse (Murine) Podoplanin Protein expressed in HEK-293 - ABIN2666857 : Kato, Fujita, Kunita, Sato, Kaneko, Osawa, Tsuruo: Molecular identification of Aggrus/T1alpha as a platelet aggregation-inducing factor expressed in colorectal tumors. in The Journal of biological chemistry 2003 (PubMed)
    Show all 8 references for ABIN2666857

  2. Human Podoplanin Protein expressed in Escherichia coli (E. coli) - ABIN667074 : Wicki, Christofori: The potential role of podoplanin in tumour invasion. in British journal of cancer 2007 (PubMed)
    Show all 2 references for ABIN667074

More Proteins for Podoplanin (PDPN) Interaction Partners

Human Podoplanin (PDPN) interaction partners

  1. In esophageal squamous cell carcinoma, high p-mTOR (show FRAP1 Proteins) expression was significantly associated with high podoplanin expression and high tumor grade

  2. These data support a role of podoplanin as an antiapoptotic prosurvival factor in angiotensin II-induced injury of human podocytes.

  3. podoplanin membrane expression, not only its localization, is a useful prognostic indicator of lung squamous cell carcinoma

  4. this study uncovers a unique molecular mechanism of lymphangiogenesis in which galectin-8 (show LGALS8 Proteins)-dependent crosstalk among VEGF-C (show VEGFC Proteins), podoplanin and integrin pathways plays a key role.

  5. Expression of Podoplanin in Non-melanoma Skin Cancers and Actinic Keratosis

  6. Almost all anti-PDPN MAbs recognize a platelet aggregation-inducing (PLAG) domain.

  7. LpMab-12 could serve as a new diagnostic tool for determining whether hPDPN possesses the sialylation on Thr52, a site-specific post-translational modification critical for the hPDPN association with CLEC-2 (show CLEC1B Proteins).

  8. podoplanin may be considered as a predictor marker in assessing malignant transformation of premalignancies and prognosis of oral malignancy

  9. Data show that the CHO cell line with the stable and high expression of recombinant podoplanin (PDPN)-enhanced green fluorescent protein (EGFP) was constructed successfully, and it could induce platelet aggregation.

  10. PDPN-positive/EpCAM (show EPCAM Proteins)-positive CTC ratio is a prognostic factor and defining the ratio in patients with HNSCC might be valuable to clinical management

Mouse (Murine) Podoplanin (PDPN) interaction partners

  1. this study uncovers a unique molecular mechanism of lymphangiogenesis in which galectin-8 (show LGALS8 Proteins)-dependent crosstalk among VEGF-C (show VEGFC Proteins), podoplanin and integrin pathways plays a key role.

  2. A reciprocal interaction between CLEC-2 (show CLEC1B Proteins) on megakaryocytes and PDPN on Bone marrow (BM) Fibroblastic reticular cell-like cells contributes to the periarteriolar megakaryopoietic microenvironment in mouse BM.

  3. Data indicate that a mechanism reliant upon blockade of proteasome-mediated E11 destabilization contributes to osteocytogenesis and that this may involve downstream targeting of RhoA (show RHOA Proteins).

  4. it is likely that PDPN, while being dispensable during re-epithelialization, has a crucial role in migration and invasion of transformed keratinocytes.

  5. Report distinct podoplanin-positive stromal cell populations and a novel progenitor subset in chronic liver inflammation and fibrosis.

  6. CLEC-2 (show CLEC1B Proteins) is an adhesive receptor that supports platelet arrest to podoplanin under venous shear. Src (show SRC Proteins)/Syk (show SYK Proteins)-dependent signalling stabilises platelet adhesion to podoplanin.

  7. Alternative NF-kappaB (show NFKB1 Proteins) signaling regulates mTEC differentiation from podoplanin-expressing presursors in the cortico-medullary junction.

  8. These results provide new insight into PDPN phosphorylation dynamics and the role of PDPN in cell motility.

  9. Podoplanin and CLEC-2 (show CLEC1B Proteins) critically drive the formation and integrity of developing cerebral blood vessels.

  10. DC-derived LTBR (show LTBR Proteins) ligands are critical mediators of lymph node cells survival, and LTBR (show LTBR Proteins) signaling on reticular stromal cells is mediated by Pdpn expression.

Podoplanin (PDPN) Protein Profile

Protein Summary

This gene encodes a type-I integral membrane glycoprotein with diverse distribution in human tissues. The physiological function of this protein may be related to its mucin-type character. The homologous protein in other species has been described as a differentiation antigen and influenza-virus receptor. The specific function of this protein has not been determined but it has been proposed as a marker of lung injury. Alternatively spliced transcript variants encoding different isoforms have been identified.

Gene names and symbols associated with Podoplanin Proteins (PDPN)

  • podoplanin (PDPN)
  • podoplanin (Pdpn)
  • podoplanin-like (LOC100738269)
  • AGGRUS protein
  • E11 protein
  • GP36 protein
  • Gp38 protein
  • GP40 protein
  • HT1A-1 protein
  • OTS-8 protein
  • OTS8 protein
  • PA2.26 protein
  • PDPN protein
  • RANDAM-2 protein
  • RTI40 protein
  • T1-alpha protein
  • T1a protein
  • T1A-2 protein
  • T1alpha protein

Protein level used designations for Podoplanin Proteins (PDPN)

podoplanin , PA2.26 antigen , T1-alpha , glycoprotein 36 , glycoprotein, 36-KD , hT1alpha-1 , hT1alpha-2 , lung type I cell membrane associated glycoprotein , lung type-I cell membrane-associated glycoprotein (T1A-2) , aggrus , glycoprotein 38 , transmembrane glycoprotein E11 , E11 antigen epitope , RTI140 , T1A , epithelial cell surface transmembrane protein antigen , pulmonary type I alveolar epithelial cell transmembrane differentiation marker , type I cell 40 kDa protein , gp38 , mucin-type membrane protein gp40

GENE ID SPECIES
456453 Pan troglodytes
10630 Homo sapiens
14726 Mus musculus
54320 Rattus norvegicus
403886 Canis lupus familiaris
509732 Bos taurus
101787585 Cavia porcellus
768390 Gallus gallus
101112240 Ovis aries
100738269 Sus scrofa
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