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The protein encoded by POGZ appears to be a zinc finger protein containing a transposase domain at the C-terminus. Additionally we are shipping POGZ Antibodies (28) and and many more products for this protein.
Data suggest that loss of function variants in POGZ lead to an identifiable syndrome of neurodevelopmental disorders with specific phenotypic traits including intellectual disability.
We find that POGZ is constitutively expressed across most tissues and has significantly higher levels of expression in the cerebellum and the pituitary gland. Disruption of POGZ is associated with intellectual disability and autism spectrum disorders
common LEDGF/p75 (show PSIP1 ELISA Kits) interaction interface shared by JPO2 (show CDCA7L ELISA Kits), PogZ, MLL1, IWS1 and HIV IN
The results reveal POGZ as an essential protein that links HP1alpha (show CBX5 ELISA Kits) dissociation with Aurora B kinase (show AURKB ELISA Kits) activation during mitosis.
LEDGF/p75 (show PSIP1 ELISA Kits) has a role in DDE domain protein function and interacts with the transposase-derived DDE domain of PogZ
The protein encoded by this gene appears to be a zinc finger protein containing a transposase domain at the C-terminus. This protein was found to interact with the transcription factor SP1 in a yeast two-hybrid system. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
pogo transposable element with ZNF domain
, pogo transposable element with ZNF domain-like
, putative protein product of Nbla00003
, zinc finger protein 280E
, zinc finger protein 635