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The protein encoded by PVR is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. Additionally we are shipping Poliovirus Receptor Proteins (26) and Poliovirus Receptor Kits (4) and many more products for this protein.
Showing 10 out of 147 products:
Mouse (Murine) Monoclonal Poliovirus Receptor Primary Antibody for BR, FACS - ABIN2663058
Mendelsohn, Wimmer, Racaniello: Cellular receptor for poliovirus: molecular cloning, nucleotide sequence, and expression of a new member of the immunoglobulin superfamily. in Cell 1989
Show all 5 references for ABIN2663058
Mouse (Murine) Monoclonal Poliovirus Receptor Primary Antibody for FACS, IF - ABIN2663060
Tahara-Hanaoka, Shibuya, Onoda, Zhang, Yamazaki, Miyamoto, Honda, Lanier, Shibuya: Functional characterization of DNAM-1 (CD226) interaction with its ligands PVR (CD155) and nectin-2 (PRR-2/CD112). in International immunology 2004
Show all 5 references for ABIN2663060
Mouse (Murine) Monoclonal Poliovirus Receptor Primary Antibody for FACS - ABIN2656944
Bottino, Castriconi, Pende, Rivera, Nanni, Carnemolla, Cantoni, Grassi, Marcenaro, Reymond, Vitale, Moretta, Lopez, Moretta: Identification of PVR (CD155) and Nectin-2 (CD112) as cell surface ligands for the human DNAM-1 (CD226) activating molecule. in The Journal of experimental medicine 2003
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Human Monoclonal Poliovirus Receptor Primary Antibody for FACS - ABIN1105910
Tahara-Hanaoka, Shibuya, Kai, Miyamoto, Morikawa, Ohkochi, Honda, Shibuya: Tumor rejection by the poliovirus receptor family ligands of the DNAM-1 (CD226) receptor. in Blood 2006
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Human Polyclonal Poliovirus Receptor Primary Antibody for WB - ABIN1881709
Nakai, Maniwa, Tanaka, Nishio, Yoshimura, Okita, Ohbayashi, Satoh, Ogita, Takai, Hayashi: Overexpression of Necl-5 correlates with unfavorable prognosis in patients with lung adenocarcinoma. in Cancer science 2010
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Human Monoclonal Poliovirus Receptor Primary Antibody for Func, FACS - ABIN180356
Nobis, Zibirre, Meyer, Kühne, Warnecke, Koch: Production of a monoclonal antibody against an epitope on HeLa cells that is the functional poliovirus binding site. in The Journal of general virology 1986
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implying that TIGIT (show TIGIT Antibodies) exerts immunosuppressive effects by competing with DNAM-1 (show CD226 Antibodies) for the same ligand, CD155
The present study provides evidence that regulation of the PVR/CD155 DNAM-1 (show CD226 Antibodies) ligand expression by nitric oxide may represent an additional immune-mediated mechanism and supports the anti-myeloma activity of nitric oxide donors.
Our findings suggest that loss of CD155 expression may play an important role in the immune escape of HCC (show FAM126A Antibodies) cells and thus CD155 may serve as a prognostic marker as well as a potential therapeutic target for HCC (show FAM126A Antibodies).
CD155 may play a critical role through both immunological and non-immuno logical mechanisms in pancreatic cancer and may be a therapeutic target for this intractable malignancy.
CD155 (PVR/Necl5) mediates a costimulatory signal in CD4 (show CD4 Antibodies)+ T cells and regulates allergic inflammation.
The cell-surface receptor (Pvr) catalyzes a large structural change in the poliovirus that exposes membrane-binding protein chains.
UPR decreases CD226 (show CD226 Antibodies) ligand CD155 expression and sensitivity to NK cell-mediated cytotoxicity in hepatoma cells.
Ala residues 10, 14 and 18 in the TM domain of Vpu are required for CD155 downregulation.
TIGIT (show TIGIT Antibodies)/PVR ligation signaling mediates suppression of IFN-gamma (show IFNG Antibodies) production via the NF-kappaB (show NFKB1 Antibodies) pathway.
UL141 can inhibit cell-surface expression of both natural killer (NK) cell-activating ligand CD155 as well as TRAIL death receptors (TRAIL-R1 and TRAIL-R2 (show TNFRSF10B Antibodies)).
Data show that CD155 protein/CD226 antigen (show CD226 Antibodies) mainly mediates the interaction between NK cells and leukemic cells in acute myeloid leukemia (show BCL11A Antibodies). To investigate the interaction between leukemic cells
absence of either CD155 or CD226 (show CD226 Antibodies) in BALB/c mice causes a profound shift in the Natural Killer T-Cells subtype composition in thymus, expanding the frequency and numbers of iNKT1 cells at the expense of iNKT2 cells, as well as iNKT17 cells.
Results suggest that modulation of the expression of receptors and CD112 (show PVRL2 Antibodies) compensates for CD155 deficiency in immune surveillance against methylcholanthrene-induced tumors.
Sertoli cells recognize the excess cytoplasm of elongated spermatids through the PVR-CEACAM2-L interaction in mouse testis
TIGIT (show TIGIT Antibodies)/PVR (show PVRL2 Antibodies) ligation signaling mediates suppression of IFN-gamma (show IFNG Antibodies) production via the NF-kappaB (show NFKB1 Antibodies) pathway.
Our data suggest that CD155 regulates T(h)2 differentiation
These observations establish a firm link between the functions of CD155 and CD226 (show CD226 Antibodies) in several T cell differentiation steps.
Necl-5/poliovirus receptor interacts with VEGFR2 (show KDR Antibodies) and regulates VEGF (show VEGFA Antibodies)-induced angiogenesis.
The TLR3 (show TLR3 Antibodies)-TRIF (show RNF138 Antibodies) mediated antiviral response is important for protection against poliovirus infection in poliovirus receptor transgenic mice.
The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene.
, nectin-like 5
, nectin-like protein 5
, tumor-associated antigen 1
, tumor-associated glycoprotein pE4