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PVRL2 encodes a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. Additionally we are shipping PVRL2 Proteins (26) and PVRL2 Kits (5) and many more products for this protein.
Showing 10 out of 129 products:
Human Monoclonal PVRL2 Primary Antibody for EIA, IHC (fro) - ABIN1105754
Sakisaka, Nakanishi, Takahashi, Mandai, Miyahara, Satoh, Takaishi, Takai: Different behavior of l-afadin and neurabin-II during the formation and destruction of cell-cell adherens junction. in Oncogene 1999
Show all 3 references for ABIN1105754
Human Monoclonal PVRL2 Primary Antibody for FACS - ABIN1449206
Tahara-Hanaoka, Shibuya, Kai, Miyamoto, Morikawa, Ohkochi, Honda, Shibuya: Tumor rejection by the poliovirus receptor family ligands of the DNAM-1 (CD226) receptor. in Blood 2006
Show all 3 references for ABIN1449206
Human Monoclonal PVRL2 Primary Antibody for EIA, IHC (fro) - ABIN1105751
Takahashi, Nakanishi, Miyahara, Mandai, Satoh, Satoh, Nishioka, Aoki, Nomoto, Mizoguchi, Takai: Nectin/PRR: an immunoglobulin-like cell adhesion molecule recruited to cadherin-based adherens junctions through interaction with Afadin, a PDZ domain-containing protein. in The Journal of cell biology 1999
Show all 3 references for ABIN1105751
Human Monoclonal PVRL2 Primary Antibody for FACS - ABIN2853602
Tahara-Hanaoka, Shibuya, Onoda, Zhang, Yamazaki, Miyamoto, Honda, Lanier, Shibuya: Functional characterization of DNAM-1 (CD226) interaction with its ligands PVR (CD155) and nectin-2 (PRR-2/CD112). in International immunology 2004
Show all 3 references for ABIN2853602
Human Monoclonal PVRL2 Primary Antibody for FACS, IHC (p) - ABIN1105750
Lopez, Cocchi, Menotti, Avitabile, Dubreuil, Campadelli-Fiume: Nectin2alpha (PRR2alpha or HveB) and nectin2delta are low-efficiency mediators for entry of herpes simplex virus mutants carrying the Leu25Pro substitution in glycoprotein D. in Journal of virology 2000
Show all 2 references for ABIN1105750
Mouse (Murine) Monoclonal PVRL2 Primary Antibody for IP, ELISA - ABIN2000751
Wang, Zhang, Wu, Chen, Xu, Zhao, Liao, Zhao, Fu, Chen, Zhu: Molecular cloning, characterization and three-dimensional modeling of porcine nectin-2/CD112. in Veterinary immunology and immunopathology 2009
Mouse (Murine) Monoclonal PVRL2 Primary Antibody for FACS - ABIN4900208
Nakata, Nakano, Okumura, Mizutani, Kinoshita, Iwai, Hasegawa, Morimoto, Fujiki, Tatsumi, Nakajima, Nakae, Nishida, Tsuboi, Oji, Oka, Sugiyama, Kumanogoh, Hosen: In vivo eradication of MLL/ENL leukemia cells by NK cells in the absence of adaptive immunity. in Leukemia 2014
Human Polyclonal PVRL2 Primary Antibody for IF (p), IHC (p) - ABIN749018
Waters, Stafman, Garner, Mruthyunjayappa, Stewart, Friedman, Coleman, Markert, Gillespie, Beierle: Effect of Repeat Dosing of Engineered Oncolytic Herpes Simplex Virus on Preclinical Models of Rhabdomyosarcoma. in Translational oncology 2016
Human Monoclonal PVRL2 Primary Antibody for FACS, IHC (fro) - ABIN119489
Lopez, Aoubala, Jordier, Isnardon, Gomez, Dubreuil: The human poliovirus receptor related 2 protein is a new hematopoietic/endothelial homophilic adhesion molecule. in Blood 1999
Results suggest that modulation of the expression of receptors and CD112 compensates for CD155 (show PVR Antibodies) deficiency in immune surveillance against methylcholanthrene-induced tumors.
We showed that cadherin and nectin (show PVRL1 Antibodies) in the junctions of A431 cells and human keratinocytes are located in separate clusters.
nectin-afadin system plays essential roles in coupling cell-cell adhesion and the cortical actin scaffold in spermatids at Sertoli-spermatid junctions and in subsequent sperm morphogenesis
Our functional analyses indicate that the infertility phenotype of nectin-2-deficient male mice is caused by a combination of reduced migration to the oviduct, spermatozoa-zona binding, and sperm-oocyte fusion
nectins and afadin (show MLLT4 Antibodies) are involved in dynamic epithelial remodeling during mouse development
Nectin-2 expression in Sertoli cells is believed via cross-talking between CREB (show CREB1 Antibodies), c-Jun (show JUN Antibodies), and Sp1 (show SP1 Antibodies) family protein.
Inactivated nectin-2 and nectin-3 disrupted the nectin-afadin-actin system, and finally the actin filaments disappeared. As a result, the specialization lost the holding function and detachment of spermatids was observed.
Nectin-2 is required to maintain structure and function of the intercalated disc and protects the heart from pressure-overload-induced cardiac dysfunction.
Serum levels of nectin-2 may have diagnostic roles for colorectal cancer patients.
Soluble form of nectin-2 is required for exerting the resistance against HSV-2 infection.
PVRL2, TOMM40 (show TOMM40 Antibodies) and APOE (show APOE Antibodies) might be associated with human longevity.
Nectin-3 (show PVRL3 Antibodies) trans-interacts with Nectin-2 to promote lymphocyte and monocyte extravasation.
Chorionic gonadotropin induces vascular endothelial growth factor (VEGFA (show VEGFA Antibodies))-dependent downregulation of nectin 2, which increases the endothelial permeability in the coculture system.
Structure of Nectin-2 reveals determinants of homophilic and heterophilic interactions that control cell-cell adhesion.
Data show that a high expression of CD112 and CD155 (show PVR Antibodies) (DNAM-1 (show CD226 Antibodies) ligands) on leukemic blasts.
a possible etiologic role of PRR2 in nonsyndromic cleft lip with or without cleft palate
The CD112 is highly expressed in colon carcinoma tissues and cell lines.
The authors now show that human cytomegalovirus targets CD112 for proteasome-mediated degradation by 48 h post-infection, thus removing both activating ligands for DNAM-1 (show CD226 Antibodies) from the cell surface during productive infection.
This gene encodes a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. This protein is one of the plasma membrane components of adherens junctions. It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in this gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
poliovirus receptor-related protein 2
, herpes virus entry mediator B
, herpesvirus entry mediator B
, murine herpes virus entry protein B
, murine herpesvirus entry protein B
, poliovirus receptor homolog
, poliovirus sensitivity
, poliovirus receptor related 2
, poliovirus receptor-related 2 (herpesvirus entry mediator B)
, herpesvirus entry protein B
, poliovirus receptor-like 2