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Inactive serine/threonine-protein kinase that plays a role in cell cycle progression and neuronal differentiation.. Additionally we are shipping PLK5 Antibodies (54) and many more products for this protein.
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The human polo-like kinase 5 gene is significantly silenced in astrocytoma and glioblastoma multiforme by promoter hypermethylation, suggesting a tumor suppressor function for thi (show BDNF Proteins)s gene.
Plk5 is mostly expressed in the brain of both mice and humans, and it modulates the formation of neuritic processes upon stimulation of the brain-derived neurotrophic factor (BDNF (show BDNF Proteins))/nerve growth factor (NGF)-Ras pathway in neurons.
DNA and protein sequence analyses show that Plk5 shares more similarities with Plk2 (show PLK2 Proteins) and Plk3 (show PLK3 Proteins) than with Plk1 and Plk4 (show PLK4 Proteins).
Inactive serine/threonine-protein kinase that plays a role in cell cycle progression and neuronal differentiation.
inactive serine/threonine-protein kinase PLK5
, polo-like kinase 5, pseudogene
, serine/threonine-protein kinase PLK5
, polo-like kinase 5 pseudogene