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Poly(A) Binding Protein, Cytoplasmic 1 (PABPC1) ELISA Kits

PABPC1 encodes a poly(A) binding protein. Additionally we are shipping Poly(A) Binding Protein, Cytoplasmic 1 Antibodies (45) and Poly(A) Binding Protein, Cytoplasmic 1 Proteins (7) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human PABPC1 PABPC1 26986 P11940
Anti-Mouse PABPC1 PABPC1 18458 P29341
Anti-Rat PABPC1 PABPC1 171350 Q9EPH8
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More ELISA Kits for Poly(A) Binding Protein, Cytoplasmic 1 Interaction Partners

Human Poly(A) Binding Protein, Cytoplasmic 1 (PABPC1) interaction partners

  1. BTG2 (show BTG2 ELISA Kits) stimulates mRNA deadenylation via CAF1 (show CHAF1B ELISA Kits) activation through interaction with PABPC1. Interaction of BTG2 (show BTG2 ELISA Kits) with the first RRM domain of PABPC1 is required for BTG2 (show BTG2 ELISA Kits) to control cell proliferation.

  2. PABPC1 is a novel co-regulator of the AR

  3. PABPC1 is upregulated in gastric carcinoma tissues, and high PABPC1 expression predicts poor survival. PABPC1 regulates proliferation and transformation of gastric cancer cells in vitro and in vivo. PABPC1 knockdown induces apoptosis.

  4. PABPC1 interacts with AGO2 (show EIF2C2 ELISA Kits) and is responsible for the microRNA mediated gene silencing in high grade hepatocellular carcinoma.

  5. Poly(A) binding protein 1 enhances cap-independent translation initiation of neurovirulence factor from avian herpesvirus

  6. Metastatic duodenal cancer cells do not tolerate intracellular PABP1 accumulation and are thus exported into the extracellular milieu by the exosome-mediated pathway. In addition, PABP1 has a potential use as a biomarker for metastatic duodenal cancer.

  7. This study highlights PABP-1 as a protein that is important to the pathology of ALS and indicates that the proteomic profile of TDP-43 inclusions in ALS may differ depending on the causative genetic mutation.

  8. PABPC1 is mislocalized in spinal cord motor neurons in amyotrophic lateral sclerosis.

  9. Study shows that PABP specifically regulates iNOS (show NOS2 ELISA Kits) mRNA stability in human DLD (show DLD ELISA Kits)-1 cells by binding to different sites in the 50- and 30-UTR (show UTS2R ELISA Kits) of the iNOS (show NOS2 ELISA Kits) mRNA. .

  10. These results suggest that production of the NSs protein during rift valley fever virus infection leads to sequestration of PABP1 in the nuclear speckles, creating a state within the cell that favors viral protein production.

Mouse (Murine) Poly(A) Binding Protein, Cytoplasmic 1 (PABPC1) interaction partners

  1. Data (including data from studies in knockout mice) suggest that Epab (embryonic poly(A)-binding protein), which is oocyte specific, is required for ability of cumulus cells and granulosa cells to exhibit responsiveness to Egf/Egfr (show EGFR ELISA Kits) signaling.

  2. Epab(-/-) oocytes are smaller in size, contain peripheral germinal vesicles, and are loosely associated with cumulus cells

  3. These findings suggest that EPAB may predominantly play roles in translational regulation of the mRNAs during early oogenesis and folliculogenesis, but PABPC1 most likely perform these roles in the later terms of ovarian development along with EPAB

  4. Epab is dispensable for mouse spermatogenesis and male fertility.

  5. We analyzed the expression of sperm-specific Akap3 (show AKAP3 ELISA Kits) and the potential regulatory factors of its protein synthesis during mouse spermiogenesis.

  6. Both Epab and Pabpc1 expression increase during early postnatal life and reach their peak at D32 testis.

  7. our data support the concept that expanded ATXN2 (show ATXN2 ELISA Kits) undergoes progressive insolubility and affects PABPC1 by a toxic gain-of-function mechanism with tissue-specific effects, which may be partially alleviated by the induction of FBXW8 (show FBXW8 ELISA Kits).

  8. EPAB is necessary for oogenesis, folliculogenesis and female fertility in mice.

  9. PABPC2 was present in pachytene spermatocytes and round spermatids, whereas elongating spermatids still included PABPC1.

Poly(A) Binding Protein, Cytoplasmic 1 (PABPC1) Antigen Profile

Antigen Summary

This gene encodes a poly(A) binding protein. The protein shuttles between the nucleus and cytoplasm and binds to the 3' poly(A) tail of eukaryotic messenger RNAs via RNA-recognition motifs. The binding of this protein to poly(A) promotes ribosome recruitment and translation initiation\; it is also required for poly(A) shortening which is the first step in mRNA decay. The gene is part of a small gene family including three protein-coding genes and several pseudogenes.

Gene names and symbols associated with PABPC1

  • poly(A) binding protein, cytoplasmic 1-like (pabpc1l) antibody
  • poly(A) binding protein, cytoplasmic 1 (pabpc1) antibody
  • poly(A) binding protein, cytoplasmic 1-like (PABPC1L) antibody
  • poly A binding protein, cytoplasmic 1 a (pabpc1a) antibody
  • poly(A) binding protein, cytoplasmic 1 (pabpc1-a) antibody
  • poly(A) binding protein, cytoplasmic 1 (PABPC1) antibody
  • poly(A) binding protein, cytoplasmic 1 (Pabpc1) antibody
  • ePAB antibody
  • fi20g03 antibody
  • pab-2 antibody
  • PAB1 antibody
  • Pabp antibody
  • Pabp1 antibody
  • pabpc1 antibody
  • PABPC2 antibody
  • PabpI antibody
  • Pabpl1 antibody
  • wu:fb16a02 antibody
  • wu:fi19b08 antibody
  • wu:fi20g03 antibody
  • wu:fj12d09 antibody
  • wu:fj61f06 antibody
  • zgc:55855 antibody
  • zgc:109879 antibody

Protein level used designations for PABPC1

polyadenylate-binding protein 1-like , poly(A) binding protein, cytoplasmic 1 , polyadenylate-binding protein 1 , PABP 1-A , PABP-1-A , PABP-A , cytoplasmic poly(A)-binding protein 1-A , poly(A)-binding protein 1-A , polyadenylate-binding protein 1-A , xPABP1-A , poly(A) binding protein, cytoplasmic 2 , PABP 1 , PABP-1 , poly(A)-binding protein 1 , poly A binding protein 1

327625 Danio rerio
448595 Xenopus (Silurana) tropicalis
711882 Macaca mulatta
606498 Danio rerio
379896 Xenopus laevis
430997 Gallus gallus
26986 Homo sapiens
612751 Canis lupus familiaris
282296 Bos taurus
18458 Mus musculus
171350 Rattus norvegicus
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