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Poly(A) Binding Protein, Cytoplasmic 4 (Inducible Form) (PABPC4) ELISA Kits

Poly(A)-binding proteins (PABPs) bind to the poly(A) tail present at the 3-prime ends of most eukaryotic mRNAs. Additionally we are shipping Poly(A) Binding Protein, Cytoplasmic 4 (Inducible Form) Antibodies (46) and and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Mouse PABPC4 PABPC4 230721  
Anti-Rat PABPC4 PABPC4 298510  
Anti-Human PABPC4 PABPC4 8761 Q13310
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More ELISA Kits for Poly(A) Binding Protein, Cytoplasmic 4 (Inducible Form) Interaction Partners

Mouse (Murine) Poly(A) Binding Protein, Cytoplasmic 4 (Inducible Form) (PABPC4) interaction partners

  1. selective depletion of PABPC4 in an erythroblast cell line inhibits terminal erythroid maturation with corresponding alterations in the erythroid gene expression

Human Poly(A) Binding Protein, Cytoplasmic 4 (Inducible Form) (PABPC4) interaction partners

  1. The PABPC4 rs4660293 SNP is associated with serum lipid levels.

  2. although function of PABPN1 (show PABPN1 ELISA Kits) may be compensated by nuclear translocation of PABP4 and perhaps by increase the cytoplasmic abundance of PABP5 (show PABPC5 ELISA Kits), these were not sufficient to prevent apoptosis of cells. PABPN1 (show PABPN1 ELISA Kits) may have an anti apoptotic role in mammalian cells

  3. PABPC4 is highly expressed in human colorectal cancer.

  4. Nuclear relocalisation of cytoplasmic poly(A)-binding proteins PABP1 and PABP4 in response to UV irradiation reveals mRNA-dependent export

  5. RNA binding masks nuclear import signals within the cytoplasmic poly(A) binding protein RNA recognition motifs, thereby ensuring ef fi cient cytoplasmic retention of this protein in normal cells

Poly(A) Binding Protein, Cytoplasmic 4 (Inducible Form) (PABPC4) Antigen Profile

Antigen Summary

Poly(A)-binding proteins (PABPs) bind to the poly(A) tail present at the 3-prime ends of most eukaryotic mRNAs. PABPC4 or IPABP (inducible PABP) was isolated as an activation-induced T-cell mRNA encoding a protein. Activation of T cells increased PABPC4 mRNA levels in T cells approximately 5-fold. PABPC4 contains 4 RNA-binding domains and proline-rich C terminus. PABPC4 is localized primarily to the cytoplasm. It is suggested that PABPC4 might be necessary for regulation of stability of labile mRNA species in activated T cells. PABPC4 was also identified as an antigen, APP1 (activated-platelet protein-1), expressed on thrombin-activated rabbit platelets. PABPC4 may also be involved in the regulation of protein translation in platelets and megakaryocytes or may participate in the binding or stabilization of polyadenylates in platelet dense granules. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with PABPC4

  • polyadenylate-binding protein 4 (Bm1_06880) antibody
  • poly(A) binding protein, cytoplasmic 4 (Pabpc4) antibody
  • poly(A) binding protein, cytoplasmic 4 (inducible form) (pabpc4) antibody
  • poly(A) binding protein, cytoplasmic 4 (inducible form) (PABPC4) antibody
  • APP-1 antibody
  • APP1 antibody
  • cb12 antibody
  • ePAB antibody
  • ePABP antibody
  • iPABP antibody
  • PABP antibody
  • PABP4 antibody
  • sb:cb12 antibody

Protein level used designations for PABPC4

polyadenylate-binding protein 4 , poly(A) binding protein, cytoplasmic 4 (inducible form) , PABP-4 , activated-platelet protein 1 , inducible poly(A)-binding protein , poly(A)-binding protein 4 , poly A binding protein, cytoplasmic 4

GENE ID SPECIES
6096303 Brugia malayi
230721 Mus musculus
298510 Rattus norvegicus
321035 Danio rerio
444284 Xenopus laevis
419674 Gallus gallus
8761 Homo sapiens
482464 Canis lupus familiaris
534576 Bos taurus
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