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anti-Poly(rC) Binding Protein 1 (PCBP1) Antibodies

This intronless gene is thought to have been generated by retrotransposition of a fully processed PCBP-2 mRNA. Additionally we are shipping PCBP1 Proteins (9) and PCBP1 Kits (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PCBP1 5093 Q15365
PCBP1 23983 P60335
PCBP1 500242  
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Top anti-PCBP1 Antibodies at antibodies-online.com

Showing 10 out of 106 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC, WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-PCBP1 Antibody Titration: 1.25ug/mlPositive Control: HepG2 cell lysate WB Suggested Anti-PCBP1  Antibody Titration: 1.25 µg/mL  Positive Control: HepG2 cell lysate  PCBP1 is supported by BioGPS gene expression data to be expressed in HepG2 100 μL Log in to see 2 to 3 Days
$229.00
Details
Dog Goat Un-conjugated EIA, WB AP22434PU-N PCBP1 antibody staining of PBMC lysate at 0.1 µg/ml (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. AP22434PU-N PCBP1 antibody staining of Rat Spleen (A) and Thymus (B) lysate at 0.1 µg/ml (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Dog Goat Un-conjugated EIA, WB AP22435PU-N PCBP1 antibody staining of HeLa lysate at 0.01 µg/ml (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated WB PCBP1 Antibody (Center) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the PCBP1 antibody detected the PCBP1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 8 to 10 Days
$493.17
Details
Human Mouse Un-conjugated ELISA, WB PCBP1 polyclonal antibody (A01), Lot # 050928JC01 Western Blot analysis of PCBP1 expression in Y-79 . Western Blot detection against Immunogen (37 KDa) . 50 μL Log in to see 9 Days
$298.57
Details
Human Rabbit Un-conjugated ELISA, WB 100 μg Log in to see 2 to 3 Days
$343.75
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details

PCBP1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Mouse (Murine)
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Rat (Rattus)
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Top referenced anti-PCBP1 Antibodies

  1. Human Polyclonal PCBP1 Primary Antibody for ELISA, WB - ABIN562120 : Neff, Lee, Wilusz, Tian, Wilusz: Global analysis reveals multiple pathways for unique regulation of mRNA decay in induced pluripotent stem cells. in Genome research 2012 (PubMed)
    Show all 3 references for ABIN562120

  2. Human Polyclonal PCBP1 Primary Antibody for IHC, WB - ABIN2778971 : Shi, Bencze, Stemmler, Philpott: A cytosolic iron chaperone that delivers iron to ferritin. in Science (New York, N.Y.) 2008 (PubMed)

  3. Dog (Canine) Polyclonal PCBP1 Primary Antibody for EIA, WB - ABIN569643 : Waggoner, Johannes, Liebhaber: Depletion of the poly(C)-binding proteins alphaCP1 and alphaCP2 from K562 cells leads to p53-independent induction of cyclin-dependent kinase inhibitor (CDKN1A) and G1 arrest. in The Journal of biological chemistry 2009 (PubMed)

  4. Cow (Bovine) Polyclonal PCBP1 Primary Antibody for WB - ABIN2778970 : Zhong, Radu, Ju, Brown: Novel progerin-interactive partner proteins hnRNP E1, EGF, Mel 18, and UBC9 interact with lamin A/C. in Biochemical and biophysical research communications 2005 (PubMed)

More Antibodies against PCBP1 Interaction Partners

Human Poly(rC) Binding Protein 1 (PCBP1) interaction partners

  1. Inhibin betaA is translationally regulated by TGFbeta (show TGFB1 Antibodies) via hnRNP E1.

  2. Suggest that PCBP1 might play an important role in preventing the process of epithelial mesenchymal transformation in NSCLC.

  3. PCBP1 mutations are recurrent in Burkitt lymphomas and might contribute, in cooperation with other mutations, to its pathogenesis.

  4. results showed for the first time that expression of PCBP1 was down-regulated in newly diagnosed acute myeloid leukemia (show BCL11A Antibodies) patients

  5. Findings provide mechanistic evidence for HOTAIR overexpression and PCBP1 downregulation in gastric cancer metastasis and their correlation with poor survival.

  6. Our proteomic profiling and subsequent validation indicate that PCBP1 is central to cancer stem cells enrichment and functionality in prostate cancer.

  7. PCBP1 is a central player in the molecular mechanism causing EMT (show ITK Antibodies) in GBC-SD cells after TGF-beta (show TGFB1 Antibodies) treatment; PCBP1 might serve as a useful biomarker for predicting prognosis of gall bladder cancer metastasis

  8. hnRNP E1 is a new regulator of protein disulphide isomerase (show P4HB Antibodies) translation in oxLDL-activated vascular endothelial cells.

  9. A novel mechanism by which POLH (show POLH Antibodies) expression is controlled by PCBP1 via mRNA stability.

  10. reduced expression of hnRNP-E1 might be involved with the cervical cancer pathogenesis, with folate playing a role in the natural history of HPV infection

Mouse (Murine) Poly(rC) Binding Protein 1 (PCBP1) interaction partners

  1. These data reveal that Pcbp1 and Pcbp2 (show PCBP2 Antibodies) are individually essential for mouse embryonic development and have distinct impacts on embryonic viability and that Pcpb2 has a nonredundant in vivo role in hematopoiesis.

  2. PCBP1 may serve as a novel maternal factor (show ZAR1 Antibodies).

  3. Our analysis of PCBP1 and PCBP2 (show PCBP2 Antibodies) expression demonstrates robust expression of these two proteins within the gastric epithelium with high concordance for both proteins in their cell-type specificities and intracellular distributions.

  4. knockdown of PCBP1 led to a reversal effect on the transcriptional inactivation during oocyte growth, which highlights the important role of PCBP1 in maintaining the gobal transcriptional silencing when the growth phase is completed

  5. TGF-beta (show TGFB1 Antibodies) modulates the expression of Dab2 (show DAB2 Antibodies) and ILEI (show FAM3C Antibodies) mRNA required for epithelial-mesenchymal transdifferentiation by inducing phosphorylation of hnRNP E1, resulting in its release from a structural, 33-nucleotide BAT (show BAAT Antibodies) element in the 3'UTR (show UTS2R Antibodies) of Dab2 (show DAB2 Antibodies) and ILEI (show FAM3C Antibodies).

  6. To define the mechanism of STAT3C suppression of transcript. and/or translational activity of NF-kappaB (show NFKB1 Antibodies) we found that a alphaCP-1 interacted with STAT3C. alphaCP-1 is a K-homol. domain-containing RNA-binding prot (show SLC6A7 Antibodies) with specific for C-rich pyrimidine tracts

PCBP1 Antigen Profile

Protein Summary

This intronless gene is thought to have been generated by retrotransposition of a fully processed PCBP-2 mRNA. This gene and PCBP-2 have paralogues (PCBP3 and PCBP4) which are thought to have arisen as a result of duplication events of entire genes. The protein encoded by this gene appears to be multifunctional. It along with PCBP-2 and hnRNPK corresponds to the major cellular poly(rC)-binding protein. It contains three K-homologous (KH) domains which may be involved in RNA binding. This encoded protein together with PCBP-2 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promote poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human Papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability.

Gene names and symbols associated with PCBP1

  • poly(rC) binding protein 1 (PCBP1) antibody
  • poly(rC) binding protein 1 (pcbp1) antibody
  • poly(rC) binding protein 1 (Pcbp1) antibody
  • alphaCP-1 antibody
  • hnRNP-E1 antibody
  • hnRNP-X antibody
  • hnRNP E1 antibody
  • HNRPE1 antibody
  • HNRPX antibody
  • PCBP1 antibody
  • RGD1561319 antibody
  • WBP17 antibody
  • [a]CP-1 antibody

Protein level used designations for PCBP1

poly(rC) binding protein 1 , poly(rC)-binding protein 1-like , alpha-CP1 , heterogeneous nuclear ribonucleoprotein E1 , heterogenous nuclear ribonucleoprotein E1 , heterogenous nuclear ribonucleoprotein X , nucleic acid-binding protein SUB2.3 , poly(rC)-binding protein 1 , hnRNP-E1 protein , hnRNP E1 , hnRNP-E1

GENE ID SPECIES
459300 Pan troglodytes
100037147 Xenopus laevis
100388387 Callithrix jacchus
100459720 Pongo abelii
5093 Homo sapiens
509917 Bos taurus
100008848 Oryctolagus cuniculus
23983 Mus musculus
500242 Rattus norvegicus
481417 Canis lupus familiaris
Selected quality suppliers for anti-PCBP1 (PCBP1) Antibodies
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