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PKD1L2 encodes a member of the polycystin protein family. Additionally we are shipping PKD1L2 Antibodies (14) and many more products for this protein.
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genes are mapped to chromosomes and gene structures are characterized; protein structure is predicted and contains strong ion channel signature motifs that suggest their possible function as components of cation channel (show TRPV1 Proteins) pores
Study found an association between a 6.2 kb dele (show KIAA0141 Proteins)- tion in the PKD1L2 gene and colorectal cancer in a Korean population.
PKD1L2 is expressed in the developing and adult heart and kidney.
Ectopic expression of PKD1L2 in transgenic mice caused severe muscle atrophy.
This gene encodes a member of the polycystin protein family. The encoded protein contains 11 transmembrane domains, a latrophilin/CL-1-like GPCR proteolytic site (GPS) domain, and a polycystin-1, lipoxygenase, alpha-toxin (PLAT) domain. This protein may function as a component of cation channel pores. Two transcript variants encoding different isoforms have been found for this gene.
PC1-like 2 protein
, polycystic kidney disease 1-like 2
, polycystic kidney disease protein 1-like 2