You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Polycystic Kidney Disease 2 (Autosomal Dominant) (PKD2) Antibodies

PKD2 encodes a member of the polycystin protein family. Additionally we are shipping PKD2 Proteins (14) and PKD2 Kits (8) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PKD2 18764 O35245
PKD2 5311 Q13563
PKD2 498328  
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top anti-PKD2 Antibodies at antibodies-online.com

Showing 10 out of 86 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of PKD2 Antibody 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Cow Goat Un-conjugated EIA, WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from NIH-3T3 cells treated with PMA 250ng/ml 15', using PKD2 (Phospho-Ser876) Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IHC, ELISA, WB Western blot analysis of extracts from NIH-3T3 cells, treated with PMA 250ng/ml 15', using PKD2 (Ab-876) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human brain tissue, using PKD2 (Ab-876) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated ICC, IF, IHC (p), WB IHC-P Image PKD2 antibody [C1C3] detects PKD2 protein at cytosol and membrane on human breast carcinoma by immunohistochemical analysis. Sample: Paraffin-embedded human breast carcinoma. PKD2 antibody [C1C3] , dilution: 1:500. ICC/IF Image PKD2 antibody [C1C3] detects PKD2 protein at cytoplasm by immunofluorescent analysis. Sample: HeLa cells were fixed in ice-cold MeOH for 5 min. Green: PKD2 protein stained by PKD2 antibody [C1C3] , diluted at 1:200. Blue: Hoechst 33342 staining. 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human kidney carcinoma labeled with Anti-Polycystin 2 Polyclonal Antibody, Unconjugated (ABIN678098) at 1:200 followed by conjugation to the secondary antibody and DAB staining. 100 μL Log in to see 3 to 7 Days
$269.50
Details
Mouse Rabbit Un-conjugated ELISA, WB   100 μg Log in to see 8 to 10 Days
$449.17
Details
Human Rabbit Un-conjugated ICC, IHC (p), WB   100 μL Log in to see 8 to 10 Days
$507.83
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 14 Days
$527.15
Details

PKD2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine) , , , ,
,

, , , , , , , , , , , , , ,
Human , , , ,
, ,
,
, , , , , , , , , , ,
Rat (Rattus) , , ,
,

, , , , , , , , , , ,

Top referenced anti-PKD2 Antibodies

  1. Human Polyclonal PKD2 Primary Antibody for EIA, WB - ABIN954155 : Duning, Rosenbusch, Schlüter, Tian, Kunzelmann, Meyer, Schulze, Markoff, Pavenstädt, Weide: Polycystin-2 activity is controlled by transcriptional coactivator with PDZ binding motif and PALS1-associated tight junction protein. in The Journal of biological chemistry 2010 (PubMed)
    Show all 5 references for ABIN954155

  2. Cow (Bovine) Polyclonal PKD2 Primary Antibody for EIA, WB - ABIN453986 : Fencl, Janda, Bláhová, Hríbal, Stekrová, Puchmajerová, Seeman: Genotype-phenotype correlation in children with autosomal dominant polycystic kidney disease. in Pediatric nephrology (Berlin, Germany) 2009 (PubMed)

More Antibodies against PKD2 Interaction Partners

Mouse (Murine) Polycystic Kidney Disease 2 (Autosomal Dominant) (PKD2) interaction partners

  1. Our studies demonstrate that PKD1 (show PKD1 Antibodies)/2 is a key regulator of MVB maturation and exosome secretion, and constitutes a mediator of the DGK alpha (show DGKA Antibodies) effect on MVB secretory traffic.

  2. Pkd2(-/-) mice with homozygous PKD2(tg)-transgene alleles (Pkd2(-/-);PKD2(tg/tg)) showed significant further amelioration of the cystic severity compared to that in Pkd2(-/-) mice

  3. Results reveal that whereas protein kinase D1 (show PRKD1 Antibodies) and protein kinase D2 are essential for neuronal polarity, there exists a functional redundancy between the two proteins.

  4. Pkd1 (show PKD1 Antibodies) and Pkd2 have coordinate effects on osteoblast differentiation and opposite effects on adipogenesis, suggesting that Pkd1 (show PKD1 Antibodies) and Pkd2 signaling pathways can have independent effects on mesenchymal lineage commitment in bone

  5. novel protein complex composed of Rabep1 (show RABEP1 Antibodies), GGA1 (show GGA1 Antibodies) and Arl3 is responsible for the sorting and targeting of the polycystin 1 (show PKD1 Antibodies) andpolycystin 2 to the cilium.

  6. PKD2 regulates directly and indirectly about 5% of the cytotoxic T-cell phosphoproteome.

  7. The results of this study demonstrate that PC1 (show PCSK1 Antibodies) trafficking and expression require GPS (show NBEAL2 Antibodies) cleavage and PC2 (show CBX4 Antibodies) interaction, respectively, and provide a framework for functional assays to categorize the effects of missense mutations in polycystins.

  8. PKD2 acted as an amplification checkpoint for antigen-stimulated digital cytokine responses and translated the differential strength of TCR signaling to determine the number of naive CD8 (show CD8A Antibodies)(+) T cells that became effector cells.

  9. In inner medullary collecting duct, flow, via polycystin-2 and P2 receptors, engages Ca(2 (show CA2 Antibodies)+)-dependent signaling pathways that stimulate ET-1 (show EDN1 Antibodies) synthesis.

  10. Pkd2(+/-) cardiomyocytes shift the beta adrenergic receptor pathway and have altered calcium handling, independent of desensitized calcium-contraction coupling.

Human Polycystic Kidney Disease 2 (Autosomal Dominant) (PKD2) interaction partners

  1. PCs expression and p53 (show TP53 Antibodies) activation as a regulator of cell proliferation were further evaluated in vivo and in 69 advanced human carotid atherosclerotic plaques.

  2. PKD2 and RSK1 (show RPS6KA1 Antibodies) regulate integrin beta4 phosphorylation at threonine 1736 to stabilize keratinocyte cell adhesion and its hemidesmosomes.

  3. The coiled-coil domain in the PC2 (show KRT6B Antibodies) C-terminal forms a stable helix bundle regardless of the presence of Ca(2 (show CA2 Antibodies)+).

  4. Results show that some of the previously reported missense or synonymous mutations in PKD2 gene caused altered pre-mRNA splicing.

  5. PKD2 is a core factor in the formation of this multiprotein complex at the TGN (show TG Antibodies) that controls constitutive secretion of matrix metalloproteinase (show MMP20 Antibodies) cargo.

  6. Human polycystin-2 transgene dose-dependently rescues autosomal-dominant polycystic kidney disease phenotypes in Pkd2 mutant mice

  7. FLNA (show FLNA Antibodies) anchors PC2 (show KRT6B Antibodies) to the actin cytoskeleton through complex PC2 (show KRT6B Antibodies)-FLNA (show FLNA Antibodies)-actin to reduce degradation and increase stability, and possibly regulate PC2 (show KRT6B Antibodies) function in a Ca-dependent manner.

  8. The data indicate that the cAMP pathway regulates PC2-mediated cation transport in the hST

  9. mutations within PKD1 (show PKD1 Antibodies) and PKD2 can be linked to most of the cases of Japanese ADPKD, and the renal function decline was faster in patients with PKD1 (show PKD1 Antibodies) mutations than in those with PKD2 mutations

  10. POlycystin-2 and its patogenic mutants inhibit PIEZO1 (show PIEZO1 Antibodies) activity in renal tubular epithelial cells.

Caenorhabditis elegans (C. elegans) Polycystic Kidney Disease 2 (Autosomal Dominant) (PKD2) interaction partners

  1. These data reveal that the STAM (show STAM Antibodies)-Hrs complex, which down-regulates ligand-activated growth factor receptors from the cell surface of yeast and mammalian cells, also regulates the localization and signaling of a ciliary PC1 (show PCSK1 Antibodies) receptor-TRPP2 complex.

  2. Results demonstrate that somatodendritic and ciliary targeting of PKD-2 requires the transmembrane region of PKD-2 and that the PKD-2 cytosolic termini regulate subcellular distribution and function.

  3. 11 mutants found with defects in the ciliary localization (cil) of C. elegans PKD-2, a transient receptor potential polycystin (TRPP) channel

PKD2 Antigen Profile

Protein Summary

This gene encodes a member of the polycystin protein family. The encoded protein is a multi-pass membrane protein that functions as a calcium permeable cation channel, and is involved in calcium transport and calcium signaling in renal epithelial cells. This protein interacts with polycystin 1, and they may be partners in a common signaling cascade involved in tubular morphogenesis. Mutations in this gene are associated with autosomal dominant polycystic kidney disease type 2.

Gene names and symbols associated with PKD2

  • polycystic kidney disease 2 (Pkd2) antibody
  • polycystic kidney disease 2 (autosomal dominant) (PKD2) antibody
  • polycystic kidney disease 2 (autosomal dominant) (Pkd2) antibody
  • protein kinase D2 (Prkd2) antibody
  • Protein PKD-2 (pkd-2) antibody
  • AI325941 antibody
  • APKD2 antibody
  • C030034P18Rik antibody
  • Pc-2 antibody
  • PC2 antibody
  • PKD2 antibody
  • PKD4 antibody
  • RGD1559992 antibody
  • TRPP2 antibody

Protein level used designations for PKD2

polycystic kidney disease 2 protein homolog , polycystin 2 , polycystin-2 , R48321 , autosomal dominant polycystic kidney disease type II protein , polycystwin , transient receptor potential cation channel, subfamily P, member 2 , polycystic kidney disease 2 homolog , polycystic kidney disease 2 membrane protein , nPKC-D2 , serine/threonine-protein kinase D2

GENE ID SPECIES
18764 Mus musculus
5311 Homo sapiens
498328 Rattus norvegicus
530393 Bos taurus
422585 Gallus gallus
487852 Canis lupus familiaris
101540 Mus musculus
178424 Caenorhabditis elegans
Selected quality suppliers for anti-PKD2 (PKD2) Antibodies
Did you look for something else?