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anti-Polyhomeotic Homolog 1 (Drosophila) (PHC1) Antibodies

PHC1 is a homolog of the Drosophila polyhomeotic gene, which is a member of the Polycomb group of genes. Additionally we are shipping and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PHC1 312690  
PHC1 1911 P78364
PHC1 13619 Q64028
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Top anti-PHC1 Antibodies at antibodies-online.com

Showing 10 out of 37 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated FACS, ELISA, WB 0.1 mg Log in to see 3 to 4 Days
$430.10
Details
Human Rabbit Un-conjugated IP, WB PHC1 MaxPab rabbit polyclonal antibody. Western Blot analysis of PHC1 expression in human colon. Immunoprecipitation of PHC1 transfected lysate using anti-PHC1 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead , and immunoblotted with PHC1 purified MaxPab mouse polyclonal antibody (B01P) . 100 μL Log in to see 9 Days
$418.57
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged PHC1 is approximately 3 ng/mL as a capture antibody. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Mouse Un-conjugated ICC, IF, IP   100 μg Log in to see 1 to 2 Days
$466.67
Details
Human Mouse Un-conjugated FACS, ELISA, WB   100 μg Log in to see 8 to 10 Days
$551.83
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged PHC1 is approximately 3ng/ml as a capture antibody. PHC1 monoclonal antibody (M05), clone 3G1. Western Blot analysis of PHC1 expression in MCF-7. 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated WB   50 μL Log in to see 8 to 10 Days
$390.50
Details
Human Rabbit Alexa Fluor 647 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 488 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 555 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details

PHC1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-PHC1 Antibodies

  1. Human Monoclonal PHC1 Primary Antibody for ICC, IF - ABIN2668352 : Miyagishima, Isono, Fujimura, Iyo, Takihara, Masumoto, Vidal, Koseki: Dissociation of mammalian Polycomb-group proteins, Ring1B and Rae28/Ph1, from the chromatin correlates with configuration changes of the chromatin in mitotic and meiotic prophase. in Histochemistry and cell biology 2003 (PubMed)
    Show all 2 references for ABIN2668352

  2. Human Polyclonal PHC1 Primary Antibody for IP, WB - ABIN515164 : Awad, Al-Dosari, Al-Yacoub, Colak, Salih, Alkuraya, Poizat: Mutation in PHC1 implicates chromatin remodeling in primary microcephaly pathogenesis. in Human molecular genetics 2013 (PubMed)

  3. Human Monoclonal PHC1 Primary Antibody for FACS, ELISA - ABIN1724838 : Boyer, Plath, Zeitlinger, Brambrink, Medeiros, Lee, Levine, Wernig, Tajonar, Ray, Bell, Otte, Vidal, Gifford, Young, Jaenisch: Polycomb complexes repress developmental regulators in murine embryonic stem cells. in Nature 2006 (PubMed)

More Antibodies against PHC1 Interaction Partners

Human Polyhomeotic Homolog 1 (Drosophila) (PHC1) interaction partners

  1. These findings reveal several cellular defects in cells carrying the PHC1 mutation and highlight the role of chromatin remodeling in the pathogenesis of PM.

  2. PcG complex 1, involving Rae28 and Cdt1 (show CDT1 Antibodies), supports the activity of hematopoietic stem cells by enhancing cycling capability and hematopoietic activity through direct regulation of Geminin (show GMNN Antibodies)

Mouse (Murine) Polyhomeotic Homolog 1 (Drosophila) (PHC1) interaction partners

  1. rae28 has a crucial role in sustaining the activity of hematopoietic stem cells to maintain hematopoiesis

  2. Gene rae28 is involved in cardiac morphogenesis (show XIRP1 Antibodies) through a non cardiomyocyte pathway. However, cardiomyocyte-specific overexpression of rae28 caused dilated cardiomyopathy.

  3. The Polycomb (show CBX2 Antibodies)-group gene Rae28 sustains Nkx2.5/Csx (show NKX2-5 Antibodies) expression and is essential for cardiac morphogenesis (show XIRP1 Antibodies).

  4. in vivo results clearly indicate that Polycomb (show CBX2 Antibodies)-group gene rae28 is indispensable for the long-term repopulating ability of HSCs

  5. polymeric Scm (show DAB1 Antibodies) complexes could extend beyond the local domains of polymeric Ph complexes on chromatin, possibly playing a role in long range repression

  6. functional overlap between Phc2 (show PhC2 Antibodies) and Phc1 along with a strict dose-dependent requirement during anterior-posterior (A-P) patterning

  7. PcG complex 1, involving Rae28 and Cdt1 (show CDT1 Antibodies), supports the activity of hematopoietic stem cells by enhancing cycling capability and hematopoietic activity through direct regulation of Geminin (show GMNN Antibodies)

PHC1 Antigen Profile

Protein Summary

This gene is a homolog of the Drosophila polyhomeotic gene, which is a member of the Polycomb group of genes. The gene product is a component of a multimeric protein complex that contains EDR2 and the vertebrate Polycomb protein BMH1. The gene product, the EDR2 protein, and the Drosophila polyhomeotic protein share 2 highly conserved domains, named homology domains I and II. These domains are involved in protein-protein interactions and may mediate heterodimerization of the protein encoded by this gene and the EDR2 protein.

Gene names and symbols associated with PHC1

  • polyhomeotic homolog 1 (Drosophila) (Phc1) antibody
  • polyhomeotic homolog 1 (Drosophila) (PHC1) antibody
  • polyhomeotic-like 1 (Drosophila) (Phc1) antibody
  • AW557034 antibody
  • Edr antibody
  • Edr1 antibody
  • HPH1 antibody
  • Mph1 antibody
  • Rae-28 antibody
  • rae28 antibody

Protein level used designations for PHC1

polyhomeotic-like 1 , polyhomeotic-like protein 1 , early development regulator 1 (homolog of polyhomeotic 1) , early development regulatory protein 1 , early development regulator1 (homolog of polyhomeotic 1)

GENE ID SPECIES
312690 Rattus norvegicus
1911 Homo sapiens
13619 Mus musculus
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