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Polyhomeotic Homolog 2 (Drosophila) Proteins (PhC2)

In Drosophila melanogaster, the 'Polycomb' group (PcG) of genes are part of a cellular memory system that is responsible for the stable inheritance of gene activity. Additionally we are shipping Polyhomeotic Homolog 2 (Drosophila) Antibodies (25) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PhC2 1912 Q8IXK0
PhC2 54383 Q9QWH1
PhC2 734530  
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Top Polyhomeotic Homolog 2 (Drosophila) Proteins at antibodies-online.com

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Xenopus laevis His tag   1 mg Log in to see 56 to 66 Days
$2,933.33
Details

PhC2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

Xenopus laevis

More Proteins for Polyhomeotic Homolog 2 (Drosophila) (PhC2) Interaction Partners

Human Polyhomeotic Homolog 2 (Drosophila) (PhC2) interaction partners

  1. these results propose a novel role of SIAH-1 in regulating the expression level of HPH2 through the ubiquitin-proteasome pathway.

Mouse (Murine) Polyhomeotic Homolog 2 (Drosophila) (PhC2) interaction partners

  1. polymerization of the Phc2 SAM (show TTN Proteins) domain is required for PRC1 (show PRC1 Proteins) clustering, chromatin condensation and gene silencing.

  2. Phc2 may act as a negative regulator that inhibits the activity of Th cells.

  3. functional overlap between Phc2 and Phc1 along with a strict dose-dependent requirement during anterior-posterior (A-P) patterning

Zebrafish Polyhomeotic Homolog 2 (Drosophila) (PhC2) interaction partners

  1. Collectively, the data argue that ph2alpha is required for epiboly and tailbud formation, acting downstream of the FGF signaling pathway

Polyhomeotic Homolog 2 (Drosophila) (PhC2) Protein Profile

Protein Summary

In Drosophila melanogaster, the 'Polycomb' group (PcG) of genes are part of a cellular memory system that is responsible for the stable inheritance of gene activity. PcG proteins form a large multimeric, chromatin-associated protein complex. The protein encoded by this gene has homology to the Drosophila PcG protein 'polyhomeotic' (Ph) and is known to heterodimerize with EDR1 and colocalize with BMI1 in interphase nuclei of human cells. The specific function in human cells has not yet been determined. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with PhC2

  • polyhomeotic homolog 2 (phc2)
  • polyhomeotic homolog 2 (Drosophila) (PHC2)
  • polyhomeotic-like 2 (Drosophila) (Phc2)
  • polyhomeotic-like 2a (Drosophila) (phc2a)
  • A3galt2 protein
  • AA415044 protein
  • cb218 protein
  • D4Ertd810e protein
  • D130050K19Rik protein
  • edr2 protein
  • HPH2 protein
  • id:ibd2745 protein
  • id:ibd5044 protein
  • Mph2 protein
  • p36 protein
  • ph2 protein
  • ph2alpha protein
  • ph2beta protein
  • ph2[a] protein
  • ph2[b] protein
  • phc2 protein
  • wu:fb98c05 protein
  • wu:fc96f07 protein
  • zgc:100775 protein
  • zgc:123102 protein

Protein level used designations for PhC2

polyhomeotic-like 2 , polyhomeotic-like protein 2 , early development regulator 2 (homolog of polyhomeotic 2) , early development regulatory protein 2 , polyhomeotic 2 , early development regulator 2 , polyhomeotic 2 protein

GENE ID SPECIES
734530 Xenopus laevis
1912 Homo sapiens
54383 Mus musculus
171465 Danio rerio
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