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anti-Polymerase (DNA Directed), gamma 2, Accessory Subunit (POLG2) Antibodies

POLG2 encodes the processivity subunit of the mitochondrial DNA polymerase gamma. Additionally we are shipping Polymerase (DNA Directed), gamma 2, Accessory Subunit Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
POLG2 303612  
POLG2 11232 Q9UHN1
POLG2 50776 Q9QZM2
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Top anti-Polymerase (DNA Directed), gamma 2, Accessory Subunit Antibodies at antibodies-online.com

Showing 10 out of 30 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human cervix carcinoma tissue, using POLG2 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB POLG2 Antibody (C-term) (ABIN1882118) flow cytometric analysis of HL-60 cells (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. POLG2 Antibody (C-term) (ABIN1882118) flow cytometric analysis of HL-60 cells (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), ELISA 100 μL Log in to see 8 to 10 Days
$478.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated IHC, ELISA 100 μg Log in to see 11 to 16 Days
$412.86
Details
Human Rabbit Un-conjugated IP, WB Immunoprecipitation of POLG2 transfected lysate using anti-POLG2 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead , and immunoblotted with POLG2 purified MaxPab mouse polyclonal antibody (B01P) . Western Blot analysis of POLG2 expression in transfected 293T cell line by POLG2 MaxPab polyclonal antibody.Lane 1: POLG2 transfected lysate(54.90 KDa).Lane 2: Non-transfected lysate. 100 μL Log in to see 9 Days
$418.57
Details
Human Mouse Un-conjugated ELISA, WB Western Blot analysis of POLG2 expression in transfected 293T cell line by POLG2 monoclonal antibody (M01), clone 1A2.Lane 1: POLG2 transfected lysate(54.9 KDa).Lane 2: Non-transfected lysate. Western Blot detection against Immunogen (79.09 KDa) . 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated IHC   100 μL Log in to see 8 to 10 Days
$375.83
Details
Human Rabbit Un-conjugated WB   50 μL Log in to see 8 to 10 Days
$463.83
Details

POLG2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Rat (Rattus)


Human , ,
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Mouse (Murine) ,


Top referenced anti-Polymerase (DNA Directed), gamma 2, Accessory Subunit Antibodies

  1. Human Polyclonal POLG2 Primary Antibody for FACS, IHC (p) - ABIN1882118 : Longley, Clark, Yu Wai Man, Hudson, Durham, Taylor, Nightingale, Turnbull, Copeland, Chinnery: Mutant POLG2 disrupts DNA polymerase gamma subunits and causes progressive external ophthalmoplegia. in American journal of human genetics 2006 (PubMed)
    Show all 2 references for ABIN1882118

  2. Human Polyclonal POLG2 Primary Antibody for IHC, ELISA - ABIN1534841 : Johnson, Tsai, Graves, Johnson: Human mitochondrial DNA polymerase holoenzyme: reconstitution and characterization. in Biochemistry 2000 (PubMed)

More Antibodies against Polymerase (DNA Directed), gamma 2, Accessory Subunit Interaction Partners

Human Polymerase (DNA Directed), gamma 2, Accessory Subunit (POLG2) interaction partners

  1. Results show that polymorphisms at POLG2 and POLRMT (show POLRMT Antibodies) increased risk of oral cancer and leukoplakia, respectively, probably modulating synthesis and activity of the enzymes.

  2. The authors describe the molecular characterization of a potential dominant POLG2 mutation (p.R369G) in a patient with autosomal dominant progressive external ophthalmoplegia and multiple mtDNA deletions.

  3. Data show that rs17650301 in POLG2 is a good candidate marker for UBC (show RPS27A Antibodies) invasiveness in Japanese males.

  4. The biochemical analysis helps explain the pathogenesis of POLG2 mutations in mitochondrial disease.

  5. human pol gammaB exhibits a catalytic subunit- and substrate DNA-dependent dimerization.

  6. PolB (show POLB Antibodies) gamma can bind double-stranded DNA and may play a role in DNA replication or repair

  7. Study represents the first structure-function analysis of the thumb subdomain in pol gamma (show POLG Antibodies) and examines the consequences of mitochondrial disease mutations in this region.

  8. Both increased and decreased expression of POLGbeta altered nucleoid structure and precipitated a marked decrease in 7S DNA molecules, which form short displacement-loops on mitochondrial DNA.

Mouse (Murine) Polymerase (DNA Directed), gamma 2, Accessory Subunit (POLG2) interaction partners

  1. Our data indicate that Polg2 function is critical to mammalian embryogenesis and mtDNA replication, and that a single copy of Polg2 is sufficient to sustain life.

Polymerase (DNA Directed), gamma 2, Accessory Subunit (POLG2) Antigen Profile

Protein Summary

This gene encodes the processivity subunit of the mitochondrial DNA polymerase gamma. The encoded protein forms a heterotrimer containing one catalytic subunit and two processivity subunits. This protein enhances DNA binding and promotes processive DNA synthesis. Mutations in this gene result in autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions.

Gene names and symbols associated with POLG2

  • polymerase (DNA directed), gamma 2, accessory subunit (Polg2) antibody
  • polymerase (DNA directed), gamma 2, accessory subunit (POLG2) antibody
  • polymerase (DNA directed), gamma 2, accessory subunit (polg2) antibody
  • HP55 antibody
  • im:7158733 antibody
  • mtpolb antibody
  • PEOA4 antibody
  • POLB antibody
  • POLG-BETA antibody
  • POLG2 antibody
  • POLGB antibody
  • si:ch211-157f15.3 antibody

Protein level used designations for POLG2

DNA polymerase subunit gamma-2, mitochondrial , polymerase (DNA directed), gamma 2, accessory subunit , DNA polymerase subunit gamma-2, mitochondrial-like , DNA polymerase gamma accessory 55 kDa subunit , mitochondrial DNA polymerase accessory subunit , mitochondrial DNA polymerase subunit gamma-2 , mitochondrial DNA polymerase, accessory subunit , p55 , mitochondrial polymerase gamma 2 , mtPolB , polG-beta , polymerase, gamma 2

GENE ID SPECIES
303612 Rattus norvegicus
417418 Gallus gallus
455266 Pan troglodytes
490910 Canis lupus familiaris
717856 Macaca mulatta
100029647 Monodelphis domestica
100064219 Equus caballus
100397872 Callithrix jacchus
100458861 Pongo abelii
100150674 Danio rerio
11232 Homo sapiens
50776 Mus musculus
505152 Bos taurus
398112 Xenopus laevis
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