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Polymerase (DNA Directed), gamma 2, Accessory Subunit (POLG2) ELISA Kits

POLG2 encodes the processivity subunit of the mitochondrial DNA polymerase gamma. Additionally we are shipping Polymerase (DNA Directed), gamma 2, Accessory Subunit Antibodies (30) and Polymerase (DNA Directed), gamma 2, Accessory Subunit Proteins (3) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Rat POLG2 POLG2 303612  
Anti-Human POLG2 POLG2 11232 Q9UHN1
Anti-Mouse POLG2 POLG2 50776 Q9QZM2
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More ELISA Kits for Polymerase (DNA Directed), gamma 2, Accessory Subunit Interaction Partners

Human Polymerase (DNA Directed), gamma 2, Accessory Subunit (POLG2) interaction partners

  1. Results show that polymorphisms at POLG2 and POLRMT increased risk of oral cancer and leukoplakia, respectively, probably modulating synthesis and activity of the enzymes.

  2. The authors describe the molecular characterization of a potential dominant POLG2 mutation (p.R369G) in a patient with autosomal dominant progressive external ophthalmoplegia and multiple mtDNA deletions.

  3. Data show that rs17650301 in POLG2 is a good candidate marker for UBC (show RPS27A ELISA Kits) invasiveness in Japanese males.

  4. The biochemical analysis helps explain the pathogenesis of POLG2 mutations in mitochondrial disease.

  5. human pol gammaB exhibits a catalytic subunit- and substrate DNA-dependent dimerization.

  6. PolB (show POLB ELISA Kits) gamma can bind double-stranded DNA and may play a role in DNA replication or repair

  7. Study represents the first structure-function analysis of the thumb subdomain in pol gamma (show POLG ELISA Kits) and examines the consequences of mitochondrial disease mutations in this region.

  8. Both increased and decreased expression of POLGbeta altered nucleoid structure and precipitated a marked decrease in 7S DNA molecules, which form short displacement-loops on mitochondrial DNA.

Mouse (Murine) Polymerase (DNA Directed), gamma 2, Accessory Subunit (POLG2) interaction partners

  1. Our data indicate that Polg2 function is critical to mammalian embryogenesis and mtDNA replication, and that a single copy of Polg2 is sufficient to sustain life.

Polymerase (DNA Directed), gamma 2, Accessory Subunit (POLG2) Antigen Profile

Antigen Summary

This gene encodes the processivity subunit of the mitochondrial DNA polymerase gamma. The encoded protein forms a heterotrimer containing one catalytic subunit and two processivity subunits. This protein enhances DNA binding and promotes processive DNA synthesis. Mutations in this gene result in autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions.

Gene names and symbols associated with POLG2

  • polymerase (DNA directed), gamma 2, accessory subunit (Polg2) antibody
  • polymerase (DNA directed), gamma 2, accessory subunit (POLG2) antibody
  • polymerase (DNA directed), gamma 2, accessory subunit (polg2) antibody
  • HP55 antibody
  • im:7158733 antibody
  • mtpolb antibody
  • PEOA4 antibody
  • POLB antibody
  • POLG-BETA antibody
  • POLG2 antibody
  • POLGB antibody
  • si:ch211-157f15.3 antibody

Protein level used designations for POLG2

DNA polymerase subunit gamma-2, mitochondrial , polymerase (DNA directed), gamma 2, accessory subunit , DNA polymerase subunit gamma-2, mitochondrial-like , DNA polymerase gamma accessory 55 kDa subunit , mitochondrial DNA polymerase accessory subunit , mitochondrial DNA polymerase subunit gamma-2 , mitochondrial DNA polymerase, accessory subunit , p55 , mitochondrial polymerase gamma 2 , mtPolB , polG-beta , polymerase, gamma 2

GENE ID SPECIES
303612 Rattus norvegicus
417418 Gallus gallus
455266 Pan troglodytes
490910 Canis lupus familiaris
717856 Macaca mulatta
100029647 Monodelphis domestica
100064219 Equus caballus
100397872 Callithrix jacchus
100458861 Pongo abelii
100150674 Danio rerio
11232 Homo sapiens
50776 Mus musculus
505152 Bos taurus
398112 Xenopus laevis
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