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Polymerase (RNA) III (DNA Directed) Polypeptide B (POLR3B) ELISA Kits

POLR3B encodes the second largest subunit of RNA polymerase III, the polymerase responsible for synthesizing transfer and small ribosomal RNAs in eukaryotes. Additionally we are shipping Polymerase (RNA) III (DNA Directed) Polypeptide B Antibodies (43) and Polymerase (RNA) III (DNA Directed) Polypeptide B Proteins (3) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Rat POLR3B POLR3B 362858  
Anti-Human POLR3B POLR3B 55703 Q9NW08
Anti-Mouse POLR3B POLR3B 70428 P59470
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More ELISA Kits for Polymerase (RNA) III (DNA Directed) Polypeptide B Interaction Partners

Human Polymerase (RNA) III (DNA Directed) Polypeptide B (POLR3B) interaction partners

  1. first reports of long deletions causing POLR3-related leukodystrophy, suggesting that deletions and duplications in POLR3A (show POLR3A ELISA Kits) or POLR3B should be investigated in patients with a compatible phenotype

  2. Mutations in POLR3A (show POLR3A ELISA Kits) or POLR3B are rare in patients with unclassified hypomyelination.

  3. INMAP as a model regulator of CENP-B (show CENPB ELISA Kits)

  4. These results suggest that INMAP might function through p53 (show TP53 ELISA Kits)/p21 (show CDKN1A ELISA Kits) pathways.

  5. Most patients with 4H leukodystrophy carried the common c.1568T>A POLR3B mutation on one allele.

  6. MRI (show C7ORF49 ELISA Kits) in patients with POLR3B mutations revealed smaller cerebellar structures, especially vermis, than those in POLR3A (show POLR3A ELISA Kits) mutations. MRI (show C7ORF49 ELISA Kits) also showed milder hypomyelination in patients with POLR3B mutations than those with POLR3A (show POLR3A ELISA Kits) mutations

  7. Investigated POLR3A (show POLR3A ELISA Kits) and POLR3B mutations in patients with genetically unexplained hypomyelinating leukodystrophies with features of Pol III-related leukodystrophies. Recessive mutations in POLR3A (show POLR3A ELISA Kits) or POLR3B were uncovered in all 14 patients.

  8. study reports INMAP is a truncated version of POLR3B, and is up-regulated in several human cancer cell lines; results suggest that INMAP may function through the p53 (show TP53 ELISA Kits) and AP-1 (show FOSB ELISA Kits) pathways, providing a possible link of its activity with tumourigenesis

  9. Mutations in POLR3A and POLR3B encoding RNA Polymerase III subunits cause an autosomal-recessive hypomyelinating leukoencephalopathy

  10. Recessive mutations in POLR3B, encoding the second largest subunit of Pol III, cause a rare hypomyelinating leukodystrophy

Mouse (Murine) Polymerase (RNA) III (DNA Directed) Polypeptide B (POLR3B) interaction partners

  1. The Polr3b in the hippocampus in the prefrontal cortex of the DBA (show RPS19 ELISA Kits)/2 J strain were up-regulated.

Polymerase (RNA) III (DNA Directed) Polypeptide B (POLR3B) Antigen Profile

Antigen Summary

This gene encodes the second largest subunit of RNA polymerase III, the polymerase responsible for synthesizing transfer and small ribosomal RNAs in eukaryotes. The largest subunit and the encoded protein form the catalytic center of RNA polymerase III. Mutations in this gene are a cause of hypomyelinating leukodystrophy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene names and symbols associated with POLR3B

  • polymerase (RNA) III (DNA directed) polypeptide B (Polr3b) antibody
  • polymerase (RNA) III (DNA directed) polypeptide B (POLR3B) antibody
  • 2700078H01Rik antibody
  • A330032P03Rik antibody
  • C128 antibody
  • C85372 antibody
  • HLD8 antibody
  • RGD1565311 antibody
  • RPC2 antibody

Protein level used designations for POLR3B

DNA-directed RNA polymerase III subunit RPC2 , DNA-directed RNA polymerase III 127.6 kDa polypeptide , DNA-directed RNA polymerase III subunit B , RNA polymerase III subunit C2 , C128 , DNA-directed RNA polymerase III B , RNA polymerase III subunit RPC2 homolog

GENE ID SPECIES
362858 Rattus norvegicus
418071 Gallus gallus
474531 Canis lupus familiaris
55703 Homo sapiens
70428 Mus musculus
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