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POLDIP3 encodes a protein that interacts with the DNA polymerase delta p50 subunit. Additionally we are shipping POLDIP3 Antibodies (64) and POLDIP3 Proteins (4) and many more products for this protein.
Altered expression of PDIP46 or its mutation may affect Pol delta (show POLD1 ELISA Kits) functions in vivo, and thereby be a nexus for altered genomic stability.
hnRNP-U (show HNRNPU ELISA Kits) inhibits TDP-43 (show TARDBP ELISA Kits)-mediated alterations in splicing of POLDIP3 mRNA.
these findings establish critical and essential roles for SKAR in the regulation of mRNA translation of IFN-sensitive genes and induction of IFN-alpha (show IFNA ELISA Kits) biological responses.
Alteration of POLDIP3 splicing associated with loss of function of TDP-43 in tissues affected with amyotrophic lateral sclerosis (ALS) .
SKAR is a specific target of S6K1 (show RPS6KB1 ELISA Kits) and regulates cell growth.
This study showed that PDIP46 aka (show NEUROG1 ELISA Kits) SKAR, a protein possessing one RNA recognition motif (RRM) and being a protein partner of both the p50 (show CD40 ELISA Kits) subunit of DNA polymerase delta (show POLD1 ELISA Kits) and p70 (show ANXA6 ELISA Kits) ribosomal protein S6 kinase 1 (S6K1 (show RPS6KB1 ELISA Kits)).
SKAR-mediated recruitment of activated S6K1 (show RPS6KB1 ELISA Kits) to newly processed mRNPs serves as a conduit between mTOR (show FRAP1 ELISA Kits) checkpoint signaling and the pioneer round of translation when cells exist in conditions supportive of protein synthesis.
This gene encodes a protein that interacts with the DNA polymerase delta p50 subunit. This protein is a specific target of S6 kinase 1 and regulates cell growth. Two transcript variants that encode different protein isoforms have been identified.
DNA polymerase delta interacting protein 3
, polymerase delta-interacting protein 3
, 46 kDa DNA polymerase delta interaction protein
, RNA-binding protein P46
, S6K1 Aly/REF-like target
, polymerase delta interacting protein 46