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The protein encoded by POLR1C is a subunit of both RNA polymerase I and RNA polymerase III complexes. Additionally we are shipping POLR1C Antibodies (51) and many more products for this protein.
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Our work therefore has uncovered tissue-specific roles for polr1c and polr1d (show POLR1D Proteins) in rRNA transcription, ribosome biogenesis, and neural crest and craniofacial development during embryogenesis.
We report a clinical and extensive molecular study, including TCOF1 (show TCOF1 Proteins), POLR1D (show POLR1D Proteins), POLR1C, and EFTUD2 (show EFTUD2 Proteins) genes, in a series of 146 patients with TCS.
Mutations in TCOF1 (show TCOF1 Proteins), POLR1C and POLR1D (show POLR1D Proteins) have all been implicated in causing TCS
mutations in both alleles of POLR1C in three individuals with Treacher Collins syndrome.
analyzed the kinetics of assembly and elongation of the RNA polymerase I complex on endogenous ribosomal genes in the nuclei of living cells with the use of in vivo microscopy
The protein encoded by this gene is a subunit of both RNA polymerase I and RNA polymerase III complexes. The encoded protein is part of the Pol core element. Defects in this gene have been associated with Treacher Collins syndrome (TCS).
DNA-directed RNA polymerases I and III subunit RPAC1
, polymerase (RNA) I polypeptide C, 30kDa
, RNA polymerase I subunit
, DNA-directed RNA polymerases I and III subunit RPAC1-like
, DNA-directed RNA polymerase I subunit C
, DNA-directed RNA polymerases I and III 40 kDa polypeptide
, RNA polymerase 1-1 (40 kDa subunit)
, RNA polymerases I and III subunit AC1
, RNA polymerase 1-1