anti-Polymerase (RNA) III (DNA Directed) Polypeptide A, 155kDa (POLR3A) Antibodies

The protein encoded by POLR3A is the catalytic component of RNA polymerase III, which synthesizes small RNAs. Additionally we are shipping Polymerase (RNA) III (DNA Directed) Polypeptide A, 155kDa Proteins (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
POLR3A 218832  
POLR3A 361102  
POLR3A 11128 O14802
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Top anti-Polymerase (RNA) III (DNA Directed) Polypeptide A, 155kDa Antibodies at antibodies-online.com

Showing 10 out of 35 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from COS/HuvEc cells, using RPC1 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated WB Western Blot: POLR3A Antibody [NBP1-53051] - Human Muscle lysate, concentration 0.2-1 ug/ml. 100 μL Log in to see 8 to 11 Days
$447.56
Details
Dog Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Un-conjugated IHC (p), IP, IHC, WB Immunohistochemistry-Paraffin: POLR3A Antibody [NBP1-30516] - Immunohistochemistry (IHC) analyzes of POLR3A Antibody in paraffin-embedded human breast carcinoma tissue. Western Blot: POLR3A Antibody [NBP1-30516] - Western blot (WB) analysis of POLR3A Antibody in extracts from HUVEC cells. 0.1 mL Log in to see 7 to 9 Days
$447.56
Details
Human Rabbit Un-conjugated ELISA, IHC, WB 100 μL Log in to see 16 Days
$175.80
Details
Human Rabbit Un-conjugated ICC, IF, IP, WB WB Image Sample (30 ug of whole cell lysate) A: HCT116 5% SDS PAGE antibody diluted at 1:500 WB Image POLR3A antibody detects POLR3A protein by western blot analysis. Various whole cell extracts (30 μg) were separated by 5% SDS-PAGE, and the membrane was blotted with POLR3A antibody , diluted at a dilution of 1:500. 100 μL Log in to see 1 to 2 Days
$358.60
Details
Chicken Rabbit Un-conjugated IHC, WB Immunohistochemical analysis of POLR3A staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated wit Western blot analysis of POLR3A expression in K562 (A), MCF7 (B), COS7 (C) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated IHC (p), WB <b>Immunohistochemistry</b> (IHC) analyzes of POLR3A antibody in paraffin-embedded human breast carcinoma tissue. <b>Western blot</b> (WB) analysis of POLR3A antibody in extracts from HUVEC cells. 0.1 mg Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 7 to 9 Days
$478.50
Details

POLR3A Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine)


Rat (Rattus)


Human , ,


, ,

Top referenced anti-Polymerase (RNA) III (DNA Directed) Polypeptide A, 155kDa Antibodies

  1. Human Polyclonal POLR3A Primary Antibody for WB - ABIN4890107 : Hu, Wu, Sun, Yuan, Kobayashi, Myers, Hernandez: Characterization of human RNA polymerase III identifies orthologues for Saccharomyces cerevisiae RNA polymerase III subunits. in Molecular and cellular biology 2002 (PubMed)

More Antibodies against Polymerase (RNA) III (DNA Directed) Polypeptide A, 155kDa Interaction Partners

Human Polymerase (RNA) III (DNA Directed) Polypeptide A, 155kDa (POLR3A) interaction partners

  1. the first transgenic mice with a leukodystrophy-causing Polr3a mutation do not recapitulate the childhood-onset hypomyelinating leukodystrophy observed in the majority of human patients with POLR3A mutations.

  2. monogenic or digenic POLR3A and POLR3C (show POLR3C Antibodies) deficiencies confer increased susceptibility to severe VZV disease in otherwise healthy children, providing evidence for an essential role of a DNA sensor in human immunity

  3. This is the first individual reported with two truncating POLR3A variants, suggesting that biallelic severe loss of function variants are associated with WRS (show KCNQ1 Antibodies). Sequencing of POLR3A and perhaps related genes such as POLR3B (show POLR3B Antibodies) in additional patients with clinical findings of WRS (show KCNQ1 Antibodies) is needed to prove this gene-disease association.

  4. Findings suggest that AP-1 factors are regulators of RNA polymerase III (Pol III)-driven 5S rRNA and U6 snRNA expression with a potential role in cell proliferation.

  5. For some of its complex functions, variation in RNAP III activity levels lead to nonuniform changes in tRNA pools that can shift the translation profiles of key codon-biased mRNAs with resultant phenotypes or disease states. (Review)

  6. Mutations in POLR3A are a frequent cause of sporadic and recessive spastic ataxia.

  7. RNA polymerase III (RNAPIII) is specialized for transcription of short, abundant nonprotein-coding RNA transcripts.

  8. Our transcriptome-wide investigations revealed an overall decrease in the levels of Pol III-transcribed tRNAs and an imbalance in the levels of regulatory ncRNAs such as small nuclear and nucleolar RNAs (snRNAs and snoRNAs).

  9. Multicenter retrospective study to collect neuroradiologic, clinical, and molecular data of patients with mutations in POLR3A and POLR3B (show POLR3B Antibodies) without the classic MRI (show C7ORF49 Antibodies) phenotype: diffuse hypomyelination is not an obligatory feature of POLR3-related disorders; two distinct patterns, selective involvement of the corticospinal tracts and cerebellar atrophy, are added to the MRI (show C7ORF49 Antibodies) presentation of POLR3-related disorders

  10. Mutations in POLR3A or POLR3B (show POLR3B Antibodies) are rare in patients with unclassified hypomyelination.

Polymerase (RNA) III (DNA Directed) Polypeptide A, 155kDa (POLR3A) Antigen Profile

Protein Summary

The protein encoded by this gene is the catalytic component of RNA polymerase III, which synthesizes small RNAs. The encoded protein also acts as a sensor to detect foreign DNA and trigger an innate immune response.

Gene names and symbols associated with POLR3A

  • polymerase (RNA) III (DNA directed) polypeptide A (Polr3a) antibody
  • polymerase (RNA) III (DNA directed) polypeptide A, 155kDa (POLR3A) antibody
  • 9330175N20Rik antibody
  • ADDH antibody
  • BC053071 antibody
  • HLD7 antibody
  • hRPC155 antibody
  • RGD1305574 antibody
  • RPC1 antibody
  • RPC155 antibody

Protein level used designations for POLR3A

DNA-directed RNA polymerase III subunit RPC1 , polymerase (RNA) III (DNA directed) polypeptide A, 155kDa , DNA-directed RNA polymerase III largest subunit , DNA-directed RNA polymerase III subunit A , RNA polymerase III 155 kDa subunit , RNA polymerase III subunit C1 , RNA polymerase III subunit C160 , RNA polymerase III subunit RPC155-D

GENE ID SPECIES
218832 Mus musculus
361102 Rattus norvegicus
11128 Homo sapiens
479256 Canis lupus familiaris
540308 Bos taurus
423727 Gallus gallus
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