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anti-Polyribonucleotide Nucleotidyltransferase 1 (PNPT1) Antibodies

PNPT1 is a subunit of the exosome complex, which is involved in 3-prime-to-5-prime exoribonuclease activity for RNA processing and degradation (Raijmakers et al., 2002. Additionally we are shipping Polyribonucleotide Nucleotidyltransferase 1 Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PNPT1 87178 Q8TCS8
PNPT1 71701 Q8K1R3
PNPT1 360992  
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Top anti-Polyribonucleotide Nucleotidyltransferase 1 Antibodies at antibodies-online.com

Showing 10 out of 65 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using PNPT1 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IHC (p), WB Human Uterus, Myometrium (formalin-fixed, paraffin-embedded) stained with PNPT1 antibody ABIN462230 followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Human Skin (formalin-fixed, paraffin-embedded) stained with PNPT1 antibody ABIN462230 followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 8 to 10 Days
$676.50
Details
Human Rabbit Un-conjugated WB PNPT1 Antibody (Center)  western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the PNPT1 antibody detected the PNPT1 protein (arrow). PNPT1 Antibody (Center)  western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the PNPT1 antibody detected the PNPT1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), ELISA 100 μL Log in to see 8 to 10 Days
$478.50
Details
Human Rabbit Un-conjugated IHC, WB Immunohistochemical analysis of PNPT1 staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Western blot analysis of PNPT1 expression in Jurkat (A), MCF7 (B), HeLa (C) whole cell lysates. 200 μL Log in to see 9 Days
$487.50
Details
Micrococcus luteus Rabbit Biotin DB, EIA, ID, IF, IP, RIA, WB   1 mL Log in to see 6 to 8 Days
$412.50
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat stomach labeled with Rabbit Anti-PNPT1 Polyclonal Antibody, Unconjugated  at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Un-conjugated ICC, IHC (p), WB   100 μL Log in to see 8 to 10 Days
$507.83
Details

PNPT1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Polyribonucleotide Nucleotidyltransferase 1 Antibodies

  1. Cow (Bovine) Polyclonal PNPT1 Primary Antibody for IHC, WB - ABIN2776602 : Slomovic, Schuster: Stable PNPase RNAi silencing: its effect on the processing and adenylation of human mitochondrial RNA. in RNA (New York, N.Y.) 2008 (PubMed)

  2. Human Polyclonal PNPT1 Primary Antibody for IHC, ELISA - ABIN1535183 : Hillier, Graves, Fulton, Fulton, Pepin, Minx, Wagner-McPherson, Layman, Wylie, Sekhon, Becker, Fewell, Delehaunty, Miner, Nash, Kremitzki, Oddy, Du, Sun, Bradshaw-Cordum, Ali, Carter, Cordes, Harris et al.: Generation and annotation of the DNA sequences of human chromosomes 2 and 4. ... in Nature 2005 (PubMed)

More Antibodies against Polyribonucleotide Nucleotidyltransferase 1 Interaction Partners

Human Polyribonucleotide Nucleotidyltransferase 1 (PNPT1) interaction partners

  1. this study provides further evidence that hPNPase(old-35) is associated with global changes in cell cycle-associated genes and identifies potential gene targets for future investigation

  2. fresh insight into cellular pathways regulated by PNPT1

  3. Interaction between PNPase and hSuv3 is essential for efficient mitochondrial RNA degradation.

  4. A mutation in PNPT1, encoding mitochondrial-RNA-import protein PNPase, causes hereditary hearing loss.

  5. Mutation in PNPT1, which encodes a polyribonucleotide nucleotidyltransferase, impairs RNA import into mitochondria and causes respiratory-chain deficiency.

  6. a novel role of nEGFR in radioresistance, and that is, upon ionizing radiation, nEGFR inactivates the ribonuclease activity of PNPase toward c-MYC (show MYC Antibodies) mRNA through DNAPK (show PRKDC Antibodies)-mediated Ser (show SIGLEC1 Antibodies)-776 phosphorylation

  7. targeted overexpression of hPNPase(old-35) represents a novel strategy to selectively downregulate RNA expression and consequently intervene in a variety of pathophysiological conditions

  8. The data support an unanticipated role for PNPASE in mediating the translocation of RNAs into mitochondria.

  9. Inhibition of PNPase by shRNA or stable overexpression of miR (show MLXIP Antibodies)-221 protected melanoma cells from IFN-beta (show IFNB1 Antibodies)-mediated growth inhibition, accentuating the importance of PNPase induction and miR (show MLXIP Antibodies)-221 down-regulation in mediating IFN-beta (show IFNB1 Antibodies) action.

  10. Protein-protein interactions between human exosome components support the assembly of RNase PH-type subunits into a six-membered PNPase-like ring

Mouse (Murine) Polyribonucleotide Nucleotidyltransferase 1 (PNPT1) interaction partners

  1. The data support an unanticipated role for PNPASE in mediating the translocation of RNAs into mitochondria

Polyribonucleotide Nucleotidyltransferase 1 (PNPT1) Antigen Profile

Protein Summary

The protein encoded by this gene belongs to the evolutionary conserved polynucleotide phosphorylase family comprised of phosphate dependent 3'-to-5' exoribonucleases implicated in RNA processing and degradation. This enzyme is predominantly localized in the mitochondrial intermembrane space and is involved in import of RNA to mitochondria. Mutations in this gene have been associated with combined oxidative phosphorylation deficiency-13 and autosomal recessive nonsyndromic deafness-70. Related pseudogenes are found on chromosomes 3 and 7.

Gene names and symbols associated with PNPT1

  • polyribonucleotide nucleotidyltransferase 1, mitochondrial (CpipJ_CPIJ005886) antibody
  • polyribonucleotide nucleotidyltransferase 1 (PNPT1) antibody
  • polyribonucleotide nucleotidyltransferase 1 (Pnpt1) antibody
  • 1200003F12Rik antibody
  • COXPD13 antibody
  • DFNB70 antibody
  • old-35 antibody
  • Old35 antibody
  • PNPase antibody
  • Pnptl1 antibody

Protein level used designations for PNPT1

polyribonucleotide nucleotidyltransferase 1, mitochondrial , 3'-5' RNA exonuclease OLD35 , PNPase 1 , PNPase old-35 , polynucleotide phosphorylase 1 , polynucleotide phosphorylase-like protein

GENE ID SPECIES
6037837 Culex quinquefasciatus
87178 Homo sapiens
481376 Canis lupus familiaris
508877 Bos taurus
71701 Mus musculus
360992 Rattus norvegicus
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