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anti-Potassium Channel, Subfamily K, Member 2 (KCNK2) Antibodies

KCNK2 encodes one of the members of the two-pore-domain background potassium channel protein family. Additionally we are shipping KCNK2 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
KCNK2 3776 O95069
KCNK2 16526 P97438
KCNK2 170899  
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Top anti-KCNK2 Antibodies at antibodies-online.com

Showing 10 out of 23 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB Western blot analysis of Trek-1 in Jurkat cell lysantes (Lane 1, 2). 3T3 cell Lysante (Lane 3), and rat kidney tissue lysante (Lane 4). 100 μg Log in to see 2 to 3 Days
$283.50
Details
Mouse Rabbit Un-conjugated ELISA, WB   100 μg Log in to see 8 to 10 Days
$419.83
Details
Human Rabbit Un-conjugated IHC, WB   100 μL Log in to see 7 to 8 Days
$454.67
Details
Mouse Rabbit Un-conjugated WB   100 μg Log in to see 8 to 10 Days
$683.83
Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 5 to 6 Days
$506.80
Details
Human Rabbit Un-conjugated ELISA, WB   100 μg Log in to see 8 to 10 Days
$669.17
Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 8 to 10 Days
$742.50
Details
Mouse Rabbit Un-conjugated WB   100 μg Log in to see 8 to 10 Days
$610.50
Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 11 to 16 Days
$559.43
Details
Human Rabbit Un-conjugated WB   50 μL Log in to see 11 to 16 Days
$936.57
Details

KCNK2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human


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Mouse (Murine) ,


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Rat (Rattus)


Top referenced anti-KCNK2 Antibodies

  1. Human Polyclonal KCNK2 Primary Antibody for IHC, WB - ABIN350410 : Ota, Suzuki, Nishikawa, Otsuki, Sugiyama, Irie, Wakamatsu, Hayashi, Sato, Nagai, Kimura, Makita, Sekine, Obayashi, Nishi, Shibahara, Tanaka, Ishii, Yamamoto, Saito, Kawai, Isono, Nakamura, Nagahari et al.: Complete sequencing and characterization of 21,243 full-length human cDNAs. ... in Nature genetics 2003 (PubMed)
    Show all 3 references for ABIN350410

More Antibodies against KCNK2 Interaction Partners

Cow (Bovine) Potassium Channel, Subfamily K, Member 2 (KCNK2) interaction partners

  1. ANG II inhibits bTREK-1 K(+) channels by a Ca(2+)-dependent mechanism that does not require the depletion of membrane-associated PIP(2).

  2. Metabolites of cAMP stimulate TREK-1 expression in adrenal cortex cells by activation of a novel cAMP-independent mechanism.

  3. TREK-1 channels may function as sensors that couple the metabolic state of the cell to membrane potential, perhaps through an associated ATP-binding protein

  4. These results identify bTREK-1 K(+) channels as a pivotal control point where ANG II (show AGT Antibodies) receptor activation is transduced to depolarization-dependent Ca(2 (show CA2 Antibodies)+) entry and aldosterone secretion.

  5. Data show that angiotensin II and paracrine factors that act through phospholipase C (show PLC Antibodies) inhibit bTREK-1 in adrenocortical cells through simultaneous activation of separate Ca2 (show CA2 Antibodies)+- and ATP hydrolysis-dependent signaling pathways.

  6. Angiotensin II (ANGII) inhibits adrenocortical cell KCNK2 in an ATP dependent, PLC/PKC independent manner.

  7. These findings demonstrate that, in addition to the well-described PKA-dependent TREK-1 inhibition, ACTH (show POMC Antibodies), NPS (show NPS Antibodies)-ACTH (show POMC Antibodies), forskolin, and 8-pCPT-2'-O-Me-cAMP also inhibit these K(+) channels by a PKA-independent signaling pathway.

Human Potassium Channel, Subfamily K, Member 2 (KCNK2) interaction partners

  1. Trek1 expression facilitates the restoration of intestinal epithelial barrier functions in an allergic environment.

  2. presence of TREK-1 variants correlated to reduced TREK-1 activity, suggesting a pathological role for TREK-1 variants in preterm labor

  3. Data suggest that potassium channel protein (show KCNQ5 Antibodies) TREK-1 (TREK-1) might be a biomarker in castration resistance free survival (CRFS) judgment of prostate cancer (PCa (show FLVCR1 Antibodies)), as well as a potential therapeutic target.

  4. During conductance simulation experiments, both TASK-3 (show KCNK9 Antibodies) and TREK-1 channels were able to repolarise the membrane once AP threshold was reached

  5. How ion channels sense mechanical force: insights from mechanosensitive K2P channels TRAAK (show KCNK4 Antibodies), TREK1, and TREK2 (show KCNK10 Antibodies).

  6. We conclude that Trek1 is critical to maintain the nasal epithelial barrier function.

  7. Nasal epithelia express Trek1 that can be suppressed by allergic response.

  8. Modulation of K2P 2.1 and K2P 10.1 K(+) channel (show KCNC4 Antibodies) sensitivity to carvedilol by alternative mRNA translation initiation

  9. Response of the human detrusor to stretch is regulated by TREK-1

  10. PLD2 (show PLD2 Antibodies), but not PLD1, directly binds to the C terminus of TREK1 and TREK2 (show KCNK10 Antibodies).

Mouse (Murine) Potassium Channel, Subfamily K, Member 2 (KCNK2) interaction partners

  1. Trek1 expression facilitates the restoration of intestinal epithelial barrier functions in an allergic environment.

  2. Data suggest that porosome-associated proteins SNAP25 (show SNAP25 Antibodies), TREK-1, syntaxin-1A (show STX1A Antibodies), and Gai3 exhibit stability and functionality such that isolated proteins can be reconstituted as insulin (show INS Antibodies)-secreting porosomes in cell membrane of live cells.

  3. Data indicate that arginine vasopressin (AVP (show AVP Antibodies)) and corticotropin-releasing hormone (CRH (show CRH Antibodies)) show additive effects on the suppression of the potassium channel subfamily K member 2 TREK-1 current via protein kinase C (show PKC Antibodies).

  4. TWIK-1 (show KCNK1 Antibodies)/TREK-1 heterodimers mediate astrocytic passive conductance and cannabinoid-induced glutamate (show GRIN1 Antibodies) release from astrocytes.

  5. In TREK1-deficient mice, brain endothelial cells displayed an inflammatory phenotype.

  6. provide new insight into membrane targeting of TREK-1 in the heart and establish a broader role for beta(IV)-spectrin (show SPTBN4 Antibodies) in organizing functional membrane domains critical for normal heart function

  7. TREK-1 channels significantly contribute to the responsiveness of Grueneberg ganglion neurons to cool temperatures.

  8. direct activation of the TREK-1 K(+) channel, acting downstream from the mu opioid receptor (show OPRM1 Antibodies), might have strong analgesic effects without opioid-like adverse effects

  9. TREK-M inhibits neuronal firing by hyperpolarizing the resting membrane potential and decreasing input resistance. Delivery of TREK-M could reduce the duration of status epilepticus and reduce neuronal death.

  10. TREK1 knockout mice exhibit altered retinal waves.

KCNK2 Antigen Profile

Protein Summary

This gene encodes one of the members of the two-pore-domain background potassium channel protein family. This type of potassium channel is formed by two homodimers that create a channel that leaks potassium out of the cell to control resting membrane potential. The channel can be opened, however, by certain anesthetics, membrane stretching, intracellular acidosis, and heat. Three transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with KCNK2

  • potassium channel, subfamily K, member 2 (KCNK2) antibody
  • potassium channel, subfamily K, member 2 (kcnk2) antibody
  • potassium channel, subfamily K, member 2 (Kcnk2) antibody
  • A430027H14Rik antibody
  • AI848635 antibody
  • hTREK-1c antibody
  • hTREK-1e antibody
  • K2p2.1 antibody
  • KCNK2 antibody
  • rTREK1d antibody
  • TPKC1 antibody
  • TREK antibody
  • Trek-1 antibody
  • TREK1 antibody

Protein level used designations for KCNK2

potassium channel subfamily K member 2 , potassium channel, subfamily K, member 2 , potassium channel subfamily K member 2-like , K2P2.1 potassium channel , TREK-1 K(+) channel subunit , TWIK-related potassium channel 1 , outward rectifying potassium channel protein TREK-1 , potassium inwardly-rectifying channel, subfamily K, member 2 , tandem-pore-domain potassium channel TREK-1 , two pore domain potassium channel TREK-1 , two pore potassium channel TPKC1 , two-pore potassium channel 1 , arachidonic acid sensitive tandem pore domain potassium channel , ion transport membrane protein

GENE ID SPECIES
282590 Bos taurus
457734 Pan troglodytes
490295 Canis lupus familiaris
708705 Macaca mulatta
770954 Gallus gallus
100023531 Monodelphis domestica
100050114 Equus caballus
100356478 Oryctolagus cuniculus
100400002 Callithrix jacchus
100435329 Pongo abelii
100481291 Ailuropoda melanoleuca
100495685 Xenopus (Silurana) tropicalis
100601855 Nomascus leucogenys
3776 Homo sapiens
16526 Mus musculus
170899 Rattus norvegicus
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