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anti-Potassium Channel, Subfamily U, Member 1 (KCNU1) Antibodies

Testis-specific potassium channel activated by both intracellular pH and membrane voltage that mediates export of K(+). Additionally we are shipping KCNU1 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
KCNU1 16532 O54982
KCNU1 157855 A8MYU2
KCNU1    
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Top anti-KCNU1 Antibodies at antibodies-online.com

Showing 10 out of 40 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated ICC, IF, IHC, WB Slo3 Rat Brain Membrane Western Blotting. 100 μg Log in to see 3 to 4 Days
$383.90
Details
Mouse Mouse Un-conjugated IHC (fro), IF, IP, WB   0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Mouse HRP ICC, IF, IHC, WB   100 μg Log in to see 3 to 4 Days
$422.40
Details
Human Mouse FITC ICC, IF, IHC, WB   100 μg Log in to see 3 to 4 Days
$426.80
Details
Human Mouse Alkaline Phosphatase (AP) ICC, IF, IHC, WB   100 μg Log in to see 3 to 4 Days
$429.00
Details
Human Mouse Biotin ICC, IF, IHC, WB   100 μg Log in to see 3 to 4 Days
$431.20
Details
Human Mouse PE ICC, IF, IHC, WB   100 μg Log in to see 3 to 4 Days
$432.30
Details
Human Mouse Streptavidin ICC, IF, IHC, WB   100 μg Log in to see 3 to 4 Days
$433.40
Details
Human Mouse APC ICC, IF, IHC, WB   100 μg Log in to see 3 to 4 Days
$434.50
Details
Human Mouse PerCP ICC, IF, IHC, WB   100 μg Log in to see 3 to 4 Days
$434.50
Details

KCNU1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine) ,
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Human
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Rat (Rattus)


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More Antibodies against KCNU1 Interaction Partners

Mouse (Murine) Potassium Channel, Subfamily U, Member 1 (KCNU1) interaction partners

  1. Considering that capacitation-induced hyperpolarization is mediated by SLO3, we evaluated the action of cSrc inhibitors on the heterologously expressed SLO3 channel.

  2. These results establish a critical role of LRRC52 in KSPER (show CATSPER1 Antibodies) channels and demonstrate that loss of a non-pore-forming auxiliary subunit results in severe fertility impairment.

  3. SLO3 K+ channels have a role in controlling calcium entry through CATSPER (show CATSPER1 Antibodies) channels in sperm

  4. Using mice lacking both SLO3 and CATSPER1 (show CATSPER1 Antibodies) subunits, the results show conclusively that the voltage-activated outward current present in Slo3 (-/-) sperm is abolished when CATSPER (show CATSPER1 Antibodies) is also deleted.

  5. SLO3-dependent hyperpolarization

  6. KSper (show CATSPER1 Antibodies)/Slo3 is the primary spermatozoan K(+) channel (show KCNC4 Antibodies), and Slo3 is critical for fertility.

  7. Phosphatidylinositol 4,5-bisphosphate activates Slo3 currents and its hydrolysis underlies the epidermal growth factor (show EGF Antibodies)-induced current inhibition

  8. Compare pharmacological properties of the pH-regulated Slo3 channel and its close homologue, the Slo1 (show KCNMA1 Antibodies) or BK channel (show KCNMA1 Antibodies).

  9. SLO3 is the principal potassium channel (show KCNAB2 Antibodies) responsible for capacitation-induced hyperpolarization, and membrane hyperpolarization is crucial to the acrosome reaction.

  10. a structurally new Mg(2 (show MCOLN1 Antibodies)+)-binding site in the RCK (show DDX6 Antibodies)/Rossman fold domain -- an intracellular structural motif that immediately follows the activation gate S6 helix -- is responsible for Mg(2 (show MCOLN1 Antibodies)+)-dependent activation

Human Potassium Channel, Subfamily U, Member 1 (KCNU1) interaction partners

  1. The authors conclude that Slo3 represents the principal K(+) channel (show KCNC4 Antibodies) in human sperm that carries the Ca(2 (show CA2 Antibodies)+)-activated IKSper current.

  2. These results present insights into the function of a protein expected to be critical for human reproduction and provide a framework to study the mechanism of pH gating in SLO3 channels.

KCNU1 Antigen Profile

Protein Summary

Testis-specific potassium channel activated by both intracellular pH and membrane voltage that mediates export of K(+). May be involved in sperm capacitation and/or the acrosome reaction, essential steps in fertilization where changes in both intracellular pH and membrane potential are known to occur. In contrast to KCNMA1/SLO1, it is not activated by Ca(2+) or Mg(2+) (By similarity).

Gene names and symbols associated with KCNU1

  • potassium channel, subfamily U, member 1 (Kcnu1) antibody
  • potassium channel, subfamily U, member 1 (KCNU1) antibody
  • KCa5 antibody
  • KCa5.1 antibody
  • Kcnma3 antibody
  • KCNMC1 antibody
  • mSlo3 antibody
  • Slo3 antibody

Protein level used designations for KCNU1

KSper , calcium-activated potassium channel subunit alpha-3 , calcium-activated potassium channel, subfamily M subunit alpha-3 , pH-sensitive maxi potassium channel , pore-forming subunit of the sperm-specific alkalization activated K(+) current , potassium channel subfamily U member 1 , potassium large conductance pH-sensitive channel, subfamily M, alpha member 3 , slowpoke homolog 3 , Calcium-activated potassium channel subunit alpha-3 , Calcium-activated potassium channel, subfamily M subunit alpha-3 , Slowpoke homolog 3

GENE ID SPECIES
16532 Mus musculus
157855 Homo sapiens
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