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KCNRG encodes a protein which regulates the activity of voltage-gated potassium channels. Additionally we are shipping Potassium Channel Regulator Antibodies (41) and many more products for this protein.
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The haploinsufficiency of KCNRG might be relevant to the progression of chronic lymphocytic leukemia (CLL)and multiple myeloma(MM) at least in a subset of patients.
KCNRG is an ER-associated protein, which is proposed to regulate Kv1 (show KCNA5 Proteins) family channel proteins by retaining a fraction of channels in endomembranes.
KCNRG suppresses K+ channel (show KCNC4 Proteins) activity in human prostate cell line LNCaP.
Results suggest that genetic alterations and the expression of KCNRG might play an important role in the development and/or progression of a subset of hepatocellular carcinoma.
Autoantibodies to KCNRG were present in 7 of the 8 patients with respiratory symptoms in autoimmune polyendocrine syndrome type 1
This gene encodes a protein which regulates the activity of voltage-gated potassium channels. This gene is on chromosome 13 and overlaps the gene for tripartite motif containing 13 on the same strand. Multiple transcript variants encoding different isoforms have been found for this gene.
potassium channel regulator
, potassium channel regulatory protein
, putative potassium channel regulatory protein
, CLLD4-like protein