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KCNK1 encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. Additionally we are shipping KCNK1 Proteins (3) and many more products for this protein.
Showing 10 out of 64 products:
Human Polyclonal KCNK1 Primary Antibody for EIA, IHC (p) - ABIN953011
Feliciangeli, Tardy, Sandoz, Chatelain, Warth, Barhanin, Bendahhou, Lesage: Potassium channel silencing by constitutive endocytosis and intracellular sequestration. in The Journal of biological chemistry 2010
Show all 5 references for ABIN953011
Human Polyclonal KCNK1 Primary Antibody for EIA, WB - ABIN953012
McGeachie, Ramoni, Mychaleckyj, Furie, Dreyfuss, Liu, Herrington, Guo, Lima, Post, Rotter, Rich, Sale, Ramoni: Integrative predictive model of coronary artery calcification in atherosclerosis. in Circulation 2009
Show all 5 references for ABIN953012
Human Polyclonal KCNK1 Primary Antibody for WB - ABIN656655
Zhou, Xu, Xie, Zhang, Schools, Ma, Kimelberg, Chen: TWIK-1 and TREK-1 are potassium channels contributing significantly to astrocyte passive conductance in rat hippocampal slices. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2009
Show all 3 references for ABIN656655
Cow (Bovine) Polyclonal KCNK1 Primary Antibody for WB - ABIN2776141
Goldstein, Bayliss, Kim, Lesage, Plant, Rajan: International Union of Pharmacology. LV. Nomenclature and molecular relationships of two-P potassium channels. in Pharmacological reviews 2005
TWIK-1 protein possesses a hydrophobic barrier deep within the inner pore
Potassium channels, in particular K2P channels, are expressed and functional in the apical membrane of airway epithelial cells
study presents the 3.4 angstrom resolution crystal structure of a human K2P channel, K2P1; an extracellular cap domain located above the selectivity filter forms an ion pathway in which K(+) ions flow through side portals
ion selectivity of TWIK-1 K+ channels during pathological hypokalemia; a molecular basis for inward leak Na+ currents that could trigger or contribute to cardiac paradoxical depolarization in lowered [K+]o; mechanism for regulating cardiac excitability.
TWIK1 is internalized via a dynamin (show DNM1 Antibodies)-dependent mechanism and addressed to the recycling endosomal compartment. Mutation in its cytoplasmic C terminus (I293A,I294A) stabilizes TWIK1 at the plasma membrane, resulting in robust currents.
Removal of the peptide adduct by SUMO protease reveals K2P1 to be a K+-selective, pH-sensitive, openly rectifying channel regulated by reversible peptide linkage.
support TWIK-1 and TREK-1 (show KCNK2 Antibodies) as being the major components of the long-sought K(+) channels underlying the passive conductance of mature hippocampal astrocytes
KCNK1 was significantly induced during osteoclast differentiation, but its functional overexpression significantly inhibited osteoclast differentiation induced by RANKL (show TNFSF11 Antibodies)
TWIK-1 is functionally expressed in dentate gyrus granule cells and contributes to the intrinsic excitability of these cells.
TWIK-1/TREK-1 (show KCNK2 Antibodies) heterodimers mediate astrocytic passive conductance and cannabinoid-induced glutamate (show GRIN1 Antibodies) release from astrocytes.
A fall in quinidine-sensitive conductance could be an adaptive response in TWIK-1 knockout ducts.
This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The product of this gene has not been shown to be a functional channel, however, it may require other non-pore-forming proteins for activity.
inward rectifying potassium channel protein TWIK-1
, potassium channel KCNO1
, potassium channel subfamily K member 1
, potassium inwardly-rectifying channel, subfamily K, member 1
, putative potassium channel TWIK
, potassium channel TWIK-1