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Potassium Channel Subfamily K Member 1 (KCNK1) ELISA Kits

KCNK1 encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. Additionally we are shipping KCNK1 Antibodies (63) and KCNK1 Proteins (3) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human KCNK1 KCNK1 3775 O00180
Anti-Rat KCNK1 KCNK1 59324 Q9Z2T2
Anti-Mouse KCNK1 KCNK1 16525 O08581
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More ELISA Kits for KCNK1 Interaction Partners

Human Potassium Channel Subfamily K Member 1 (KCNK1) interaction partners

  1. TWIK-1 protein possesses a hydrophobic barrier deep within the inner pore

  2. Potassium channels, in particular K2P channels, are expressed and functional in the apical membrane of airway epithelial cells

  3. study presents the 3.4 angstrom resolution crystal structure of a human K2P channel, K2P1; an extracellular cap domain located above the selectivity filter forms an ion pathway in which K(+) ions flow through side portals

  4. ion selectivity of TWIK-1 K+ channels during pathological hypokalemia; a molecular basis for inward leak Na+ currents that could trigger or contribute to cardiac paradoxical depolarization in lowered [K+]o; mechanism for regulating cardiac excitability.

  5. TWIK1 is internalized via a dynamin (show DNM1 ELISA Kits)-dependent mechanism and addressed to the recycling endosomal compartment. Mutation in its cytoplasmic C terminus (I293A,I294A) stabilizes TWIK1 at the plasma membrane, resulting in robust currents.

  6. Removal of the peptide adduct by SUMO protease reveals K2P1 to be a K+-selective, pH-sensitive, openly rectifying channel regulated by reversible peptide linkage.

  7. support TWIK-1 and TREK-1 (show KCNK2 ELISA Kits) as being the major components of the long-sought K(+) channels underlying the passive conductance of mature hippocampal astrocytes

Mouse (Murine) Potassium Channel Subfamily K Member 1 (KCNK1) interaction partners

  1. KCNK1 was significantly induced during osteoclast differentiation, but its functional overexpression significantly inhibited osteoclast differentiation induced by RANKL (show TNFSF11 ELISA Kits)

  2. TWIK-1 is functionally expressed in dentate gyrus granule cells and contributes to the intrinsic excitability of these cells.

  3. TWIK-1/TREK-1 (show KCNK2 ELISA Kits) heterodimers mediate astrocytic passive conductance and cannabinoid-induced glutamate (show GRIN1 ELISA Kits) release from astrocytes.

  4. ion selectivity of TWIK-1 K+ channels during pathological hypokalemia; a molecular basis for inward leak Na+ currents that could trigger or contribute to cardiac paradoxical depolarization in lowered [K+]o; mechanism for regulating cardiac excitability.

  5. A fall in quinidine-sensitive conductance could be an adaptive response in TWIK-1 knockout ducts.

KCNK1 Antigen Profile

Antigen Summary

This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The product of this gene has not been shown to be a functional channel, however, it may require other non-pore-forming proteins for activity.

Gene names and symbols associated with KCNK1

  • potassium channel, subfamily K, member 1 (KCNK1) antibody
  • potassium channel, subfamily K, member 1 (Kcnk1) antibody
  • potassium channel, subfamily K, member 1 (kcnk1) antibody
  • AI788889 antibody
  • DPK antibody
  • HOHO antibody
  • K2P1 antibody
  • k2p1.1 antibody
  • KCNO1 antibody
  • rabKCNK1 antibody
  • Twik antibody
  • twik-1 antibody
  • twik1 antibody

Protein level used designations for KCNK1

inward rectifying potassium channel protein TWIK-1 , potassium channel KCNO1 , potassium channel subfamily K member 1 , potassium inwardly-rectifying channel, subfamily K, member 1 , putative potassium channel TWIK , rTWIK , potassium channel TWIK-1

GENE ID SPECIES
3775 Homo sapiens
59324 Rattus norvegicus
379125 Xenopus laevis
505563 Bos taurus
100008962 Oryctolagus cuniculus
16525 Mus musculus
100135567 Cavia porcellus
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