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May repress the transcriptional activity of AP-2 family members, including TFAP2A, TFAP2B and TFAP2C to various extent (By similarity). Additionally we are shipping KCTD1 Proteins (5) and KCTD1 Kits (4) and many more products for this protein.
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Human Polyclonal KCTD1 Primary Antibody for IHC (p), WB - ABIN651146
Ding, Luo, Zhou, Zhong, Hu, Zhou, Ren, Gan, He, Zhu, Gao, Zhang: The interaction of KCTD1 with transcription factor AP-2alpha inhibits its transactivation. in Journal of cellular biochemistry 2009
Show all 2 references for ABIN651146
these results identify a novel PrP(C (show PRNP Antibodies))-interacting protein KCTD1 and suggest a new approach to investigating the unidentified physiological cellular function of PrP(C (show PRNP Antibodies)).
The authors find that the KCTD proteins 5, 6, 9 and 17 bind to Cul3 (show CUL3 Antibodies) with high affinity, while the KCTD proteins 1 and 16 do not have detectable binding.
KCTD1 functions as a novel inhibitor of Wnt (show WNT2 Antibodies) signaling p
Mutations in KCTD1 cause scalp-ear-nipple syndrome.
indicate the novel function of KCTD1 as the transcriptional repressor for AP-2 (show GTF3A Antibodies) family, especially for AP-2alpha (show TFAP2A Antibodies)
May repress the transcriptional activity of AP-2 family members, including TFAP2A, TFAP2B and TFAP2C to various extent (By similarity).
BTB/POZ domain-containing protein KCTD1
, potassium channel tetramerization domain containing 1
, potassium channel tetramerisation domain containing 1
, potassium channel tetramerization domain-containing protein 1
, vitamin A-deficient testicular protein 5
, vitamin A-deficient testicular protein 6