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Its interaction with CUL3 suggests that it may act as a substrate adapter in some E3 ligase complex. Additionally we are shipping KCTD5 Antibodies (8) and KCTD5 Kits (5) and many more products for this protein.
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Human KCTD5 Protein expressed in Escherichia coli (E. coli) - ABIN1098451
Bayón, Trinidad, de la Puerta, Del Carmen Rodríguez, Bogetz, Rojas, De Pereda, Rahmouni, Williams, Matsuzawa, Reed, Crespo, Mustelin, Alonso: KCTD5, a putative substrate adaptor for cullin3 ubiquitin ligases. in The FEBS journal 2008
Show all 2 references for ABIN1098451
Identification of MCM7, ZNF711 and FAM193 as KCTD5 interaction partners.KCTD5 is not involved in polyubiquitylation of MCM7 replication factor.The KCTD5/cullin3 complex stabilizes ZNF711 transcription factor.
we have identified a novel cellular AAV-2 Rep78/Rep68 interaction partner, KCTD5, located predominantly in the cytoplasm.
Analysis of the interaction with cullin3 showed that, in addition to the BTB domain, some amino acids in the N-terminus of KCTD5 are required for binding to cullin3. Findings suggest that KCTD5 is a substrate-specific adaptor for cullin3-based E3 ligases
Its interaction with CUL3 suggests that it may act as a substrate adapter in some E3 ligase complex. Does not affect the function of Kv channel Kv2.1/KCNB1, Kv1.2/KCNA2, Kv4.2/KCND2 and Kv3.4/KCNC4 (By similarity).
BTB/POZ domain-containing protein KCTD5
, potassium channel tetramerisation domain containing 5