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Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Additionally we are shipping KCTD8 Antibodies (36) and KCTD8 Proteins (3) and many more products for this protein.
Data suggest that the distinct spatial and temporal distribution patterns of KCTD8, 12, 12b, and 16 underlie functional differences in native GABA(B) responses.
Data indicate that median methylation levels of BCAN (show BCAN ELISA Kits), HOXD1 (show HOXD1 ELISA Kits), KCTD8, KLF11 (show KLF11 ELISA Kits), NXPH1 (show NXPH1 ELISA Kits), POU4F1 (show POU4F1 ELISA Kits), SIM1 (show SIM1 ELISA Kits), and TCF7L1 (show TCF3 ELISA Kits) were >/=30% higher than in normal samples, representing potential biomarkers for tumor diagnosis.
KCTD8 might modulate adverse effects of smoking during pregnancy on brain development via apoptosis triggered by low intracellular levels of potassium, possibly reducing the number of progenitor cells
Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and promoting desensitization.
BTB/POZ domain-containing protein KCTD8
, potassium channel tetramerisation domain containing 8