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Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Additionally we are shipping KCTD8 Antibodies (35) and KCTD8 Kits (5) and many more products for this protein.
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Data suggest that the distinct spatial and temporal distribution patterns of KCTD8, 12, 12b, and 16 underlie functional differences in native GABA(B) responses.
Data indicate that median methylation levels of BCAN (show BCAN Proteins), HOXD1 (show HOXD1 Proteins), KCTD8, KLF11 (show KLF11 Proteins), NXPH1 (show NXPH1 Proteins), POU4F1 (show POU4F1 Proteins), SIM1 (show SIM1 Proteins), and TCF7L1 (show TCF3 Proteins) were >/=30% higher than in normal samples, representing potential biomarkers for tumor diagnosis.
KCTD8 might modulate adverse effects of smoking during pregnancy on brain development via apoptosis triggered by low intracellular levels of potassium, possibly reducing the number of progenitor cells
Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and promoting desensitization.
BTB/POZ domain-containing protein KCTD8
, potassium channel tetramerisation domain containing 8