You are viewing an incomplete version of our website. Please click to reload the website as full version.

Potassium Intermediate/small Conductance Calcium-Activated Channel, Subfamily N, Member 2 (KCNN2) ELISA Kits

Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Additionally we are shipping KCNN2 Antibodies (35) and and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
KCNN2 3781 Q9H2S1
Anti-Mouse KCNN2 KCNN2 140492 P58390
Anti-Rat KCNN2 KCNN2 54262 P70604
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top KCNN2 ELISA Kits at antibodies-online.com

Showing 2 out of 5 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.059 ng/mL 0.15-10 ng/mL 96 Tests Log in to see 9 to 11 Days
$810.53
Details
Please inquire
  10 reactions Log in to see 4 to 6 Days
$549.00
Details

More ELISA Kits for KCNN2 Interaction Partners

Human Potassium Intermediate/small Conductance Calcium-Activated Channel, Subfamily N, Member 2 (KCNN2) interaction partners

  1. Differentiated dopaminergic neurons expressed low levels of SK2 channels and high levels of SK1 and SK3 channels.

  2. KCNN2 gene can have an important role in the development of coronary artery aneurysms in Kawasaki disease.

  3. Increase in both Ca(2 (show CA2 ELISA Kits)+) sensitivity and SK2 protein expression contributes to the IKAS upregulation in failing human ventricles.

  4. Decreased expression of small-conductance Ca2 (show CA2 ELISA Kits)+-activated K+ channels SK1 (show KCNN1 ELISA Kits) and SK2 in human chronic atrial fibrillation

  5. RT-PCR analysis showed strong expression of SK2 mRNA in the normal human colon.

  6. Because of the marked differential expression of SK2 channels in the heart, specific ligands for Ca2 (show CA2 ELISA Kits)+-activated K+ currents may offer a unique therapeutic opportunity to modify atrial cells without interfering with ventricular myocytes

  7. SK2 plays an important role in mediating the increase in transepithelial secretion due to increases in intracellular Ca 2 (show CA2 ELISA Kits)+. SK2 channels, therefore, may represent a target for pharmacologic modulation of bile flow.

  8. The subtype SK2 channels were up-regulated under hypoxia, shown with pharmacological tools and with mRNA analysis.

  9. Functions of SK2 channels in atrial myocytes are critically dependent on the normal expression of Ca(v)1.3 (show CACNA1D ELISA Kits) Ca(2 (show CA2 ELISA Kits)+) channels.

  10. Results suggest that SK2-channel activation may largely contribute to the sustained Ca2 (show CA2 ELISA Kits)+ influx in the G0/G1 phase in comparison of that in the G2/M phase in Jurkat T-lymphocytes.

Mouse (Murine) Potassium Intermediate/small Conductance Calcium-Activated Channel, Subfamily N, Member 2 (KCNN2) interaction partners

  1. Atrial SK2 and SK3 are significantly down-regulated from accelerated turnover in diabetic mice, resulting in action potential prolongation and arrhythmias.

  2. enhanced SK2 channel control over NMDAR contributes to LTP impairment via increased PP2A activity following context dependent sensitization to morphine.

  3. This study reveleated that outer hair cells of SK2 (show PAPSS2 ELISA Kits) knockout mice had few small efferent terminals. Synaptic cisterns were present, but smaller than those of wild-type littermates.

  4. SK2 and SK3 channels are expressed in different populations of motoneurons in rats and mice but not in cats

  5. Mitochondrial small conductance SK2 (show PAPSS2 ELISA Kits) channels prevent glutamate (show GRIN1 ELISA Kits)-induced oxytosis and mitochondrial dysfunction.

  6. Virtually all Cav2.1 (show CACNA1A ELISA Kits) clusters are colocalized in Purkinje cells with two types of calcium-activated potassium channels, SK2 (show PAPSS2 ELISA Kits) and BK.

  7. A developmental increase and gradient in SK2 (show PAPSS2 ELISA Kits)-containing channel surface expression is found that underlie the influence on neurotransmission.

  8. Sleep spindle occurrence is shaped by SK2 (show PAPSS2 ELISA Kits)-channel-mediated repetitive reticular thalamic nucleus neuron bursting & contributes to augmented NREMS consolidation & arousal threshold.

  9. Long-lasting plasticity of intrinsic excitability in dendrites results from changes in the gain of the SK2 (show PAPSS2 ELISA Kits) channel regulatory mechanism of neurons.

  10. increasing SK2 (show PAPSS2 ELISA Kits) channel activity, or preventing ischemia-induced loss of synaptic SK2 (show PAPSS2 ELISA Kits) channels, are promising and novel approaches to neuroprotection following cerebral ischemia

KCNN2 Antigen Profile

Antigen Summary

Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. The protein encoded by this gene is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. This gene is a member of the KCNN family of potassium channel genes. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with KCNN2

  • potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2 (KCNN2) antibody
  • potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2 (LOC100230275) antibody
  • potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2 (Kcnn2) antibody
  • fri antibody
  • hSK2 antibody
  • KCa2.2 antibody
  • KCNN2 antibody
  • SK2 antibody
  • SKCA2 antibody
  • SKCa 2 antibody

Protein level used designations for KCNN2

potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2 , small conductance calcium-activated potassium channel protein 2 , small-conductance calcium-activated potassium channel , apamin-sensitive small-conductance Ca2+-activated potassium channel , small conductance potassium channel type 2 , SKCa 2 , small conductance calcium-activated potassium channel subfamily N member 2 , SK2 , SKCa2 , small conductance calcium-activated channel, subfamily N, member 2

GENE ID SPECIES
695374 Macaca mulatta
100016183 Monodelphis domestica
100172000 Pongo abelii
100230275 Taeniopygia guttata
100589687 Nomascus leucogenys
395579 Gallus gallus
3781 Homo sapiens
474640 Canis lupus familiaris
404177 Bos taurus
140492 Mus musculus
54262 Rattus norvegicus
Selected quality suppliers for KCNN2 (KCNN2) ELISA Kits
Did you look for something else?