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anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 1 (KCNJ1) Antibodies

Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. Additionally we are shipping Potassium Inwardly-Rectifying Channel, Subfamily J, Member 1 Proteins (10) and Potassium Inwardly-Rectifying Channel, Subfamily J, Member 1 Kits (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
KCNJ1 3758 P48048
KCNJ1 24521 P35560
KCNJ1 56379 O88335
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Top anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 1 Antibodies at antibodies-online.com

Showing 10 out of 80 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Dog Rabbit Un-conjugated WB WB Suggested Anti-KCNJ1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated IF, IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human brain, using ROMK/Kir1.1 (Phospho-Ser44/25) Antibody. The picture on the right is treated with the synthesized peptide. Immunofluorescence analysis of A549 cells, using ROMK/Kir1.1 (Phospho-Ser44/25) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IF, ELISA Immunofluorescence analysis of A549 cells, using ROMK/Kir1.1 (Ab-44/25) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated WB KCNJ1 Antibody (C-term)  western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the KCNJ1 antibody detected the KCNJ1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated IF, ELISA 100 μL Log in to see 8 to 10 Days
$478.50
Details
Human Goat Un-conjugated ELISA, WB 100 μg Log in to see 8 to 10 Days
$595.83
Details

KCNJ1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 1 Antibodies

  1. Dog (Canine) Polyclonal KCNJ1 Primary Antibody for WB - ABIN2776290 : Tobin, Tomaszewski, Braund, Hajat, Raleigh, Palmer, Caulfield, Burton, Samani: Common variants in genes underlying monogenic hypertension and hypotension and blood pressure in the general population. in Hypertension 2008 (PubMed)

  2. Human Polyclonal KCNJ1 Primary Antibody for WB - ABIN375086 : Ji, Foo, ORoak, Zhao, Larson, Simon, Newton-Cheh, State, Levy, Lifton: Rare independent mutations in renal salt handling genes contribute to blood pressure variation. in Nature genetics 2008 (PubMed)

More Antibodies against Potassium Inwardly-Rectifying Channel, Subfamily J, Member 1 Interaction Partners

Cow (Bovine) Potassium Inwardly-Rectifying Channel, Subfamily J, Member 1 (KCNJ1) interaction partners

  1. The findings support ROMK as the pore-forming subunit of the cytoprotective mitoK(ATP) channel in heart mitochondria.

Human Potassium Inwardly-Rectifying Channel, Subfamily J, Member 1 (KCNJ1) interaction partners

  1. WNK4 (show WNK4 Antibodies) is a substrate of SFKs and the association of c-Src (show SRC Antibodies) and PTP-1D (show PTPN11 Antibodies) with WNK4 (show WNK4 Antibodies) at Tyr (show TYR Antibodies)(1092) and Tyr (show TYR Antibodies)(1143) plays an important role in modulating the inhibitory effect of WNK4 (show WNK4 Antibodies) on ROMK

  2. knockdown of KCNJ1 in HK-2 (show HK2 Antibodies) cells promoted cell proliferation. Collectively, these data highlight that KCNJ1, low-expressed in ccRCC and associated with poor prognosis, plays an important role in ccRCC cell growth and metastasis

  3. The association between polymorphisms in KCNJ1, SLC12A1 (show SLC12A1 Antibodies), and 7 other genes and calcium intake and colorectal neoplasia risk was studied.

  4. A KCNJ1 SNP was associated with increased FG during HCTZ treatment.

  5. Molecular analysis revealed a compound heterozygous mutation in the KCNJ1 gene, consisting of a novel K76E and an already described V315G mutation, both affecting functional domains of the channel protein.

  6. Findings suggest that 11q24 is a susceptible locus for openness, with KCNJ1 as the possible candidate gene.

  7. no mutation in the KCNJ1 gene, among patients suffering from bartter and Gitelman syndromes

  8. PI3K (show PIK3CA Antibodies)-activating hormones inhibit ROMK by enhancing its endocytosis via a mechanism that involves phosphorylation of WNK1 (show WNK1 Antibodies) by Akt1 (show AKT1 Antibodies) and SGK1 (show SGK1 Antibodies).

  9. THGP (show UMOD Antibodies) modulation of ROMK function confers a new role of THGP (show UMOD Antibodies) on renal ion transport and may contribute to salt wasting observed in FJHN/MCKD-2 (show UMOD Antibodies)/GCKD patients.

  10. KCNJ1 mutations are associated with Bartter syndrome.

Mouse (Murine) Potassium Inwardly-Rectifying Channel, Subfamily J, Member 1 (KCNJ1) interaction partners

  1. Suggest that the hyperkalemia in knock-in mouse with the CUL3 (show CUL3 Antibodies)(Delta403-459) mutation is not caused by reduced ROMK expression in the distal nephron.

  2. animal knockouts of ROMK1 do not produce Bartter phenotype. ROMK1 is critical in response to high K intake-stimulated K+ secretion in the collecting tubule.

  3. Lovastatin stimulates ROMK1 channels by inducing PI(4,5)P2 synthesis, suggesting that the drug could reduce cyclosporine-induced nephropathy.

  4. ROMK1 protein abundance and activity are down-regulated by SPAK (show STK39 Antibodies) and OSR1 (show OSR1 Antibodies)

  5. It was concluded that miR (show MLXIP Antibodies)-194 regulates ROMK channel activity by modulating ITSN1 (show ITSN1 Antibodies) expression thereby enhancing ITSN1 (show ITSN1 Antibodies)/WNK-dependent endocytosis.

  6. THGP (show UMOD Antibodies) modulation of ROMK function confers a new role of THGP (show UMOD Antibodies) on renal ion transport and may contribute to salt wasting observed in FJHN/MCKD-2 (show UMOD Antibodies)/GCKD patients.

  7. hypertension resistance sequence variants inhibit ROMK channel function by different mechanisms

  8. Absence of small conductance K+ channel (show KCNC4 Antibodies) (SK) activity in apical membranes of thick ascending limb and cortical collecting duct in knockout mice a model for bartter's disease__

  9. SGK-1 (show SGK1 Antibodies) phosphorylation of ROMK drives expression on the plasmalemma; because SGK-1 (show SGK1 Antibodies) is an early aldosterone-induced gene, results suggest a possible molecular mechanism for aldosterone-dependent regulation of the secretory potassium channel (show KCNAB2 Antibodies) in the kidney

  10. ROMK is required for functional expression of the 70-pS K channel (show KCNC4 Antibodies) in the thick ascending limb.

Zebrafish Potassium Inwardly-Rectifying Channel, Subfamily J, Member 1 (KCNJ1) interaction partners

  1. Kcnj1 is expressed in cells associated with osmoregulation and acts as a K+ efflux pathway that is important in maintaining extracellular levels of potassium ion in the developing embryo.

Potassium Inwardly-Rectifying Channel, Subfamily J, Member 1 (KCNJ1) Antigen Profile

Protein Summary

Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. It is activated by internal ATP and probably plays an important role in potassium homeostasis. The encoded protein has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Mutations in this gene have been associated with antenatal Bartter syndrome, which is characterized by salt wasting, hypokalemic alkalosis, hypercalciuria, and low blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with KCNJ1

  • potassium inwardly-rectifying channel, subfamily J, member 1 (KCNJ1) antibody
  • potassium inwardly-rectifying channel, subfamily J, member 1 (kcnj1) antibody
  • potassium inwardly-rectifying channel, subfamily J, member 15 (kcnj15) antibody
  • potassium inwardly-rectifying channel, subfamily J, member 1 (Kcnj1) antibody
  • potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 1 (kcnj1a.1) antibody
  • Kcnj antibody
  • kcnj1 antibody
  • kir1.1 antibody
  • MGC68935 antibody
  • ROMK antibody
  • romk1 antibody
  • Romk2 antibody
  • wu:fl37c05 antibody
  • zgc:63534 antibody

Protein level used designations for KCNJ1

potassium inwardly-rectifying channel, subfamily J, member 1 , spliced potassium channels ROM-K1, ROM-K2, ROM-K3, ROM-K4, ROM-K5 and ROM-K6 , potassium inwardly-rectifying channel J1 , ATP-sensitive inward rectifier potassium channel 1 , ATP-sensitive inward rectifier potassium channel 1-like , potassium inwardly-rectifying channel, subfamily J, member 15 , ATP-regulated potassium channel ROM-K , inward rectifier K(+) channel Kir1.1 , inwardly rectifying K+ channel , potassium channel, inwardly rectifying subfamily J member 1 , K+ channel protein , KAB-1 , Potassium inwardly-rectifying channel subfamily J , kir1.1 , inwardly rectifying potassium channel ROMK-2

GENE ID SPECIES
281882 Bos taurus
428236 Gallus gallus
466846 Pan troglodytes
539250 Bos taurus
714848 Macaca mulatta
100072580 Equus caballus
100173141 Pongo abelii
100470569 Ailuropoda melanoleuca
100487609 Xenopus (Silurana) tropicalis
100517668 Sus scrofa
100556003 Anolis carolinensis
100579741 Nomascus leucogenys
379692 Xenopus laevis
3758 Homo sapiens
24521 Rattus norvegicus
56379 Mus musculus
447262 Xenopus laevis
489285 Canis lupus familiaris
386933 Danio rerio
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