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Potassium Inwardly-Rectifying Channel, Subfamily J, Member 1 (KCNJ1) ELISA Kits

Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. Additionally we are shipping Potassium Inwardly-Rectifying Channel, Subfamily J, Member 1 Antibodies (80) and Potassium Inwardly-Rectifying Channel, Subfamily J, Member 1 Proteins (10) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
KCNJ1 3758 P48048
KCNJ1 24521 P35560
KCNJ1 56379 O88335
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More ELISA Kits for Potassium Inwardly-Rectifying Channel, Subfamily J, Member 1 Interaction Partners

Cow (Bovine) Potassium Inwardly-Rectifying Channel, Subfamily J, Member 1 (KCNJ1) interaction partners

  1. The findings support ROMK as the pore-forming subunit of the cytoprotective mitoK(ATP) channel in heart mitochondria.

Human Potassium Inwardly-Rectifying Channel, Subfamily J, Member 1 (KCNJ1) interaction partners

  1. WNK4 (show WNK4 ELISA Kits) is a substrate of SFKs and the association of c-Src (show SRC ELISA Kits) and PTP-1D (show PTPN11 ELISA Kits) with WNK4 (show WNK4 ELISA Kits) at Tyr (show TYR ELISA Kits)(1092) and Tyr (show TYR ELISA Kits)(1143) plays an important role in modulating the inhibitory effect of WNK4 (show WNK4 ELISA Kits) on ROMK

  2. knockdown of KCNJ1 in HK-2 (show HK2 ELISA Kits) cells promoted cell proliferation. Collectively, these data highlight that KCNJ1, low-expressed in ccRCC and associated with poor prognosis, plays an important role in ccRCC cell growth and metastasis

  3. The association between polymorphisms in KCNJ1, SLC12A1 (show SLC12A1 ELISA Kits), and 7 other genes and calcium intake and colorectal neoplasia risk was studied.

  4. A KCNJ1 SNP was associated with increased FG during HCTZ treatment.

  5. Molecular analysis revealed a compound heterozygous mutation in the KCNJ1 gene, consisting of a novel K76E and an already described V315G mutation, both affecting functional domains of the channel protein.

  6. Findings suggest that 11q24 is a susceptible locus for openness, with KCNJ1 as the possible candidate gene.

  7. no mutation in the KCNJ1 gene, among patients suffering from bartter and Gitelman syndromes

  8. PI3K (show PIK3CA ELISA Kits)-activating hormones inhibit ROMK by enhancing its endocytosis via a mechanism that involves phosphorylation of WNK1 (show WNK1 ELISA Kits) by Akt1 (show AKT1 ELISA Kits) and SGK1 (show SGK1 ELISA Kits).

  9. THGP (show UMOD ELISA Kits) modulation of ROMK function confers a new role of THGP (show UMOD ELISA Kits) on renal ion transport and may contribute to salt wasting observed in FJHN/MCKD-2 (show UMOD ELISA Kits)/GCKD patients.

  10. KCNJ1 mutations are associated with Bartter syndrome.

Mouse (Murine) Potassium Inwardly-Rectifying Channel, Subfamily J, Member 1 (KCNJ1) interaction partners

  1. Suggest that the hyperkalemia in knock-in mouse with the CUL3 (show CUL3 ELISA Kits)(Delta403-459) mutation is not caused by reduced ROMK expression in the distal nephron.

  2. animal knockouts of ROMK1 do not produce Bartter phenotype. ROMK1 is critical in response to high K intake-stimulated K+ secretion in the collecting tubule.

  3. Lovastatin stimulates ROMK1 channels by inducing PI(4,5)P2 synthesis, suggesting that the drug could reduce cyclosporine-induced nephropathy.

  4. ROMK1 protein abundance and activity are down-regulated by SPAK (show STK39 ELISA Kits) and OSR1 (show OSR1 ELISA Kits)

  5. It was concluded that miR (show MLXIP ELISA Kits)-194 regulates ROMK channel activity by modulating ITSN1 (show ITSN1 ELISA Kits) expression thereby enhancing ITSN1 (show ITSN1 ELISA Kits)/WNK-dependent endocytosis.

  6. THGP (show UMOD ELISA Kits) modulation of ROMK function confers a new role of THGP (show UMOD ELISA Kits) on renal ion transport and may contribute to salt wasting observed in FJHN/MCKD-2 (show UMOD ELISA Kits)/GCKD patients.

  7. hypertension resistance sequence variants inhibit ROMK channel function by different mechanisms

  8. Absence of small conductance K+ channel (show KCNC4 ELISA Kits) (SK) activity in apical membranes of thick ascending limb and cortical collecting duct in knockout mice a model for bartter's disease__

  9. SGK-1 (show SGK1 ELISA Kits) phosphorylation of ROMK drives expression on the plasmalemma; because SGK-1 (show SGK1 ELISA Kits) is an early aldosterone-induced gene, results suggest a possible molecular mechanism for aldosterone-dependent regulation of the secretory potassium channel (show KCNAB2 ELISA Kits) in the kidney

  10. ROMK is required for functional expression of the 70-pS K channel (show KCNC4 ELISA Kits) in the thick ascending limb.

Zebrafish Potassium Inwardly-Rectifying Channel, Subfamily J, Member 1 (KCNJ1) interaction partners

  1. Kcnj1 is expressed in cells associated with osmoregulation and acts as a K+ efflux pathway that is important in maintaining extracellular levels of potassium ion in the developing embryo.

Potassium Inwardly-Rectifying Channel, Subfamily J, Member 1 (KCNJ1) Antigen Profile

Antigen Summary

Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. It is activated by internal ATP and probably plays an important role in potassium homeostasis. The encoded protein has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Mutations in this gene have been associated with antenatal Bartter syndrome, which is characterized by salt wasting, hypokalemic alkalosis, hypercalciuria, and low blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with KCNJ1

  • potassium inwardly-rectifying channel, subfamily J, member 1 (KCNJ1) antibody
  • potassium inwardly-rectifying channel, subfamily J, member 1 (kcnj1) antibody
  • potassium inwardly-rectifying channel, subfamily J, member 15 (kcnj15) antibody
  • potassium inwardly-rectifying channel, subfamily J, member 1 (Kcnj1) antibody
  • potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 1 (kcnj1a.1) antibody
  • Kcnj antibody
  • kcnj1 antibody
  • kir1.1 antibody
  • MGC68935 antibody
  • ROMK antibody
  • romk1 antibody
  • Romk2 antibody
  • wu:fl37c05 antibody
  • zgc:63534 antibody

Protein level used designations for KCNJ1

potassium inwardly-rectifying channel, subfamily J, member 1 , spliced potassium channels ROM-K1, ROM-K2, ROM-K3, ROM-K4, ROM-K5 and ROM-K6 , potassium inwardly-rectifying channel J1 , ATP-sensitive inward rectifier potassium channel 1 , ATP-sensitive inward rectifier potassium channel 1-like , potassium inwardly-rectifying channel, subfamily J, member 15 , ATP-regulated potassium channel ROM-K , inward rectifier K(+) channel Kir1.1 , inwardly rectifying K+ channel , potassium channel, inwardly rectifying subfamily J member 1 , K+ channel protein , KAB-1 , Potassium inwardly-rectifying channel subfamily J , kir1.1 , inwardly rectifying potassium channel ROMK-2

GENE ID SPECIES
281882 Bos taurus
428236 Gallus gallus
466846 Pan troglodytes
539250 Bos taurus
714848 Macaca mulatta
100072580 Equus caballus
100173141 Pongo abelii
100470569 Ailuropoda melanoleuca
100487609 Xenopus (Silurana) tropicalis
100517668 Sus scrofa
100556003 Anolis carolinensis
100579741 Nomascus leucogenys
379692 Xenopus laevis
3758 Homo sapiens
24521 Rattus norvegicus
56379 Mus musculus
447262 Xenopus laevis
489285 Canis lupus familiaris
386933 Danio rerio
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