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Potassium Inwardly-Rectifying Channel, Subfamily J, Member 4 Proteins (KCNJ4)

Several different potassium channels are known to be involved with electrical signaling in the nervous system. Additionally we are shipping KCNJ4 Antibodies (78) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
KCNJ4 3761 P48050
KCNJ4 16520  
Rat KCNJ4 KCNJ4 116649 P52190
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Top KCNJ4 Proteins at antibodies-online.com

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details

KCNJ4 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine) ,
,

More Proteins for Potassium Inwardly-Rectifying Channel, Subfamily J, Member 4 (KCNJ4) Interaction Partners

Human Potassium Inwardly-Rectifying Channel, Subfamily J, Member 4 (KCNJ4) interaction partners

  1. Increased excitability and decreased dendritic arborization are associated with downregulation of inward rectifier potassium channels (Kir2.1 (show KCNJ2 Proteins)/2.3).

  2. Kir2.2 (show KCNJ12 Proteins) and Kir2.1 (show KCNJ2 Proteins) are primary determinants of endogenous K(+) conductance in HAECs under resting conditions and that Kir2.2 (show KCNJ12 Proteins) provides the dominant conductance in these cells.

  3. Results describe the regulation of inwardly rectifying potassium current and its main molecular correlates, Kir2.1 (show KCNJ2 Proteins), Kir2.2 (show KCNJ12 Proteins) and Kir2.3 channels, by endothelin-1 (show EDN1 Proteins) in human atrial cardiomyocytes.

  4. Kir2.3 is internalized by an AP-2 clathrin-dependent mechanism.

  5. possibility of intramolecular interactions of the residue Kir2.3(H117) with conserved cysteines in close proximity to the selectivity filter

  6. The data suggest that Kir2.3 plays a potentially important role in I(K1) currents in neonatal rat cardiomyocytes.

  7. TIP-1 (show TAX1BP3 Proteins) may act as an important regulator for the endocytic pathway of Kir2.3.

Mouse (Murine) Potassium Inwardly-Rectifying Channel, Subfamily J, Member 4 (KCNJ4) interaction partners

  1. changes in these proteins and their modification may predispose striatal projection neurons to dysfunction and then degeneratation in Huntington disease (show HTT Proteins)

  2. K+ currents attributable to Kir2.2 (show KCNJ12 Proteins)/2.3 and K+-selective leak (Kleak) channels are prominent in layer V-VI pyramidal neurons in slices of prelimbic and infralimbic cortex

  3. Kir2.3 channels do not contribute to cardiac inward rectifier (show KCNJ5 Proteins) potassium currents.

  4. Enhanced interaction with PIP(2) is the molecular mechanism for Kir2.3 channel activation by arachidonic acid.

KCNJ4 Protein Profile

Protein Summary

Several different potassium channels are known to be involved with electrical signaling in the nervous system. One class is activated by depolarization whereas a second class is not. The latter are referred to as inwardly rectifying K+ channels, and they have a greater tendency to allow potassium to flow into the cell rather than out of it. This asymmetry in potassium ion conductance plays a key role in the excitability of muscle cells and neurons. The protein encoded by this gene is an integral membrane protein and member of the inward rectifier potassium channel family. The encoded protein has a small unitary conductance compared to other members of this protein family. Two transcript variants encoding the same protein have been found for this gene.

Gene names and symbols associated with KCNJ4

  • potassium inwardly-rectifying channel, subfamily J, member 4 (KCNJ4)
  • potassium inwardly-rectifying channel, subfamily J, member 4 (Kcnj4)
  • CKIR2.3 protein
  • HIR protein
  • Hirk2 protein
  • HRK1 protein
  • IRK-3 protein
  • IRK3 protein
  • Kcnf2 protein
  • KCNJ4 protein
  • Kir2.3 protein
  • MB-IRK3 protein

Protein level used designations for KCNJ4

potassium inwardly-rectifying channel, subfamily J, member 4 , inward-rectifying potassium channel cKir2.3 , potassium inwardly-rectifying channel J4 , hippocampal inward rectifier potassium channel , inward rectifier K(+) channel Kir2.3 , inward rectifier K+ channel Kir2.3 , inward rectifier potassium channel 4 , potassium channel, inwardly rectifying subfamily J member 4 , IRK-3 , Kir 2.3 , BIR11 , IRK3 , brain inwardly rectifying K(+) channel 2

GENE ID SPECIES
395903 Gallus gallus
470209 Pan troglodytes
100338640 Oryctolagus cuniculus
3761 Homo sapiens
16520 Mus musculus
116649 Rattus norvegicus
481253 Canis lupus familiaris
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