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Potassium Inwardly-Rectifying Channel, Subfamily J, Member 6 Proteins (KCNJ6)

Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. Additionally we are shipping Potassium Inwardly-Rectifying Channel, Subfamily J, Member 6 Antibodies (62) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
KCNJ6 3763 P48051
KCNJ6 16522 P48542
KCNJ6 25743 P48550
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Top Potassium Inwardly-Rectifying Channel, Subfamily J, Member 6 Proteins at antibodies-online.com

Showing 7 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 11 to 12 Days
$246.96
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   5 applications Log in to see 1 to 2 Days
$312.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

KCNJ6 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, ,
Mouse (Murine) ,
,
Rat (Rattus)

More Proteins for Potassium Inwardly-Rectifying Channel, Subfamily J, Member 6 (KCNJ6) Interaction Partners

Human Potassium Inwardly-Rectifying Channel, Subfamily J, Member 6 (KCNJ6) interaction partners

  1. The findings of this study suggest that variations in KCNJ6 genes are associated with both mild and severe persistent breast pain after breast cancer surgery.

  2. KCNJ6 (GIRK2) gene polymorphism rs2835859 could serve as a marker that predicts sensitivity to analgesics and pain and susceptibility to nicotine dependence.

  3. In this transgenic mouse model, GIRK2 plays a major role in the genesis of infantile spasms.

  4. Keppen-Lubinsky syndrome is caused by mutations in the inwardly rectifying K+ channel (show KCNJ1 Proteins) encoded by KCNJ6.

  5. For KCNJ6, three SNPs (i.e., rs2835914, rs8129919, rs2836050) were associated with the occurrence of preoperative breast pain.

  6. Ethanol associates directly with the GIRK channel, leading to enhanced interaction with a membrane phospholipid phosphatidylinositol 4,5-bisphosphate and activation of the channel.

  7. 3.5 A resolution crystal structure of the mammalian GIRK2 channel in complex with betagamma G-protein subunits, the central signalling complex that links G-protein-coupled receptor (show ADRA1A Proteins) stimulation to K(+) channel (show KCNC4 Proteins) activity

  8. KCNJ6 (or its product GIRK2) accounts for some of the variations in frontal theta; band oscillations.

  9. Conformational information encoded by ligand binding to delta-opioid receptors (DORs) is transmitted to Kir3.1 (show KCNJ3 Proteins)/Kir3.2 channels.

  10. GIRK2 is expressed in nearly every human pigmented neuron or mouse tyrosine hydroxylase-immunoreactive (show TH Proteins) neuron in both the substantia nigra and ventral tegmental areas.

Mouse (Murine) Potassium Inwardly-Rectifying Channel, Subfamily J, Member 6 (KCNJ6) interaction partners

  1. Results indicate that GIRK channels formed by GIRK2 subunits determine depression-related behaviors as well as basal and 5-HT1A receptor (show CC2D1A Proteins)-mediated dorsal raphe neuronal activity

  2. This study showed that spontaneous GIRK2 mutations causing cerebellar pathology are impaired in motor functions during the neonatal period.

  3. This study demonstrated that the residue Ser-196 in Kir3.2 is involved in conferring PKC-mediated inhibition to the channel.

  4. In the ventral tegmental area, GABA neurons express both GIRK2 (and GIRK1 (show KCNJ3 Proteins)) subunits.

  5. Gbeta (show SUCLG2 Proteins)-gamma and PIP2 must be present simultaneously to activate GIRK2.

  6. Ligand-operated activation of Kir3.2 appears to cause dilation of the pore at the cytoplasmic domain, and is regulated conformationally.

  7. A subcellular GIRK2c/GIRK3 (show KCNJ9 Proteins) pathway is identified that regulates excitability of ventral tegmental area dopamine neurons.

  8. The results of this study show that Girk2 gene mutation alters electric activity of LC neurons in vivo.

  9. GIRK2 mediates the mGluR (show GRM8 Proteins)-sensitive current in unipolar brush cells

  10. GIRK2 is expressed in nearly every human pigmented neuron or mouse immunoreactive tyrosine hydroxylase (show TH Proteins)-immunoreactive neuron in both the substantia nigra and ventral tegmental areas.

Potassium Inwardly-Rectifying Channel, Subfamily J, Member 6 (KCNJ6) Protein Profile

Protein Summary

Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and may be involved in the regulation of insulin secretion by glucose. It associates with two other G-protein-activated potassium channels to form a heteromultimeric pore-forming complex.

Gene names and symbols associated with KCNJ6

  • potassium inwardly-rectifying channel, subfamily J, member 6 (KCNJ6)
  • potassium inwardly-rectifying channel, subfamily J, member 6 (kcnj6)
  • potassium inwardly-rectifying channel, subfamily J, member 6 (Kcnj6)
  • BIR1 protein
  • GIRK-2 protein
  • GIRK2 protein
  • hiGIRK2 protein
  • KATP-2 protein
  • KATP2 protein
  • kcnj6 protein
  • KCNJ7 protein
  • Kir3.2 protein
  • weaver protein
  • wv protein

Protein level used designations for KCNJ6

potassium inwardly-rectifying channel, subfamily J, member 6 , G-protein-coupled inward rectifier potassium channel , G protein-activated inward rectifier potassium channel 2 , inward rectifier K(+) channel Kir3.2 , inward rectifier potassium channel KIR3.2 , GIRK-2 , potassium channel, inwardly rectifying subfamily J member 6 , potassium inwardly-rectifying channel J6 , BIR1 , GIRK2 , KATP-2 , Inward rectifier K(+) channel Kir3.2 , Potassium channel, inwardly rectifying subfamily J member 6 , potassium channel-like protein

GENE ID SPECIES
427983 Gallus gallus
520743 Bos taurus
549655 Xenopus (Silurana) tropicalis
100625084 Sus scrofa
3763 Homo sapiens
16522 Mus musculus
25743 Rattus norvegicus
101823647 Mesocricetus auratus
100174134 Pongo abelii
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