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Potassium Inwardly-Rectifying Channel, Subfamily J, Member 8 (KCNJ8) ELISA Kits

Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. Additionally we are shipping KCNJ8 Antibodies (66) and KCNJ8 Proteins (4) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
KCNJ8 3764 Q15842
KCNJ8 16523 P97794
KCNJ8 25472 Q63664
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Top KCNJ8 ELISA Kits at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Human
96 Tests Log in to see 16 to 21 Days
$999.43
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Chicken
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$999.43
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Mouse
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$999.43
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Rat
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$999.43
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More ELISA Kits for KCNJ8 Interaction Partners

Human Potassium Inwardly-Rectifying Channel, Subfamily J, Member 8 (KCNJ8) interaction partners

  1. KCNJ8-S422L as pathogenic for J-wave syndromes failed to appropriately account for European population structure and the variant is likely benign, or (b) Ashkenazi Jews may be at significantly increased risk of J-wave syndromes

  2. We identified a de novo missense mutation encoding Kir6.1[p.Cys176Ser] in the patient. Kir6.1[p.Cys176Ser] channels exhibited markedly higher activity than wild-type channels, as a result of reduced ATP sensitivity.

  3. Data indicate that pharmacological KvLQT1 (show KCNQ1 ELISA Kits) and KATP (Kir6.1) inhibition or silencing with siRNAs down-regulated alpha-ENaC (show SCNN1A ELISA Kits) expression.

  4. The KCNJ8-S422L variant was shown to be associated with both increased susceptibility to atrial fibrillation and early repolarization.

  5. results suggest that acting on the 3'-UTR (show UTS2R ELISA Kits) of Kir6.1 and the coding region of SUR2B (show ABCC9 ELISA Kits), methylglyoxal causes instability of Kir6.1 and SUR2B (show ABCC9 ELISA Kits) mRNAs, disruption of vascular K(ATP) channels, and impairment of arterial function

  6. Data suggest that Kir6.1 and M3 muscarinic receptor (show CHRM3 ELISA Kits) colocalize to detrusor caveolae; studies include tissue from both male and female subjects.

  7. The researchers report evidence that the KCNJ8 gene increases susceptiblity to the brugada syndrome and early repolarization syndrome.

  8. The mutations localized to Kir6.1's C-terminus, involved conserved residues and the pinacidil-activated K(ATP) current was decreased 45% to 68% for Kir6.1-E332del and 40% to 57% for V346I between -20 mV and 40 mV.

  9. Down-regulation of Kir6.1 and Kir6.2 (show KCNJ11 ELISA Kits) expression in myometrium may contribute to the enhanced uterine contractility associated with the onset of labour.

  10. Interaction with caveolin-1 causes a shift the channel's sensitivity to its physiological regulator magnesium ADP (MgADP).

Mouse (Murine) Potassium Inwardly-Rectifying Channel, Subfamily J, Member 8 (KCNJ8) interaction partners

  1. Kcnj8 mutation is responsible of heart conduction abnormalities in Cantu (show ABCC9 ELISA Kits) syndrome.

  2. our study demonstrated that exercise training up-regulated Kir6.1, improved tissue oxygenation recovery, and protected the heart against I/R injury

  3. Results suggest that the vascular KATP channel Kcnj8 is organ protective in diabetic conditions.

  4. The absence of Kir6.1 does not affect the contractile properties of myocytes during stress, suggesting the absence of Kir6.1 improves myocyte tolerance to stress via an unknown mechanism.

  5. Sulfhydration of SUR2B (show ABCC9 ELISA Kits) subunit modifies tyrosine nitration of Kir6.1 subunit within the KATP channel complex.

  6. Kir6.1 underlies the vascular smooth muscle KATP channel and has a key role in vascular reactivity and blood pressure control.

  7. Native K(ATP) channels in mouse vas (show AVP ELISA Kits) deferens myocytes are a heterocomplex of K(IR)6.1 channels and SUR2B (show ABCC9 ELISA Kits) subunits.

  8. Kir6.1 knockdown exacerbates cerebral ischemia reperfusion-induced brain damage.

  9. A possible partnership between Cx43 (show GJA1 ELISA Kits) and Kir6.1 will help in better understanding their roles in ischemia/hypoxia preconditioning.

  10. Report unique properties of the ATP-sensitive potassium channel (show KCNAB2 ELISA Kits) in the mouse ventricular cardiac conduction system.

Pig (Porcine) Potassium Inwardly-Rectifying Channel, Subfamily J, Member 8 (KCNJ8) interaction partners

  1. Results describe a new function of the Kir6.1-SUR2A (show ABCC9 ELISA Kits) complex, namely the regulation of paracellular permeability through tight junctions.

  2. The predominant K(ATP) channel expressed in pig urethral smooth muscle possesses a unique, heteromeric pore structure with a pore-forming subunit composition of (Kir6.1)(3)-(Kir6.2 (show KCNJ11 ELISA Kits)).

  3. Kir6.1/SUR2B is the major functional K(ATP) channel complex in the pig MMA and MCA, and mRNA expression studies suggest that the human MMA shares this K(ATP) channel subunit profile

KCNJ8 Antigen Profile

Antigen Summary

Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins. Defects in this gene may be a cause of J-wave syndromes and sudden infant death syndrome (SIDS).

Gene names and symbols associated with KCNJ8

  • potassium inwardly-rectifying channel, subfamily J, member 8 (KCNJ8) antibody
  • potassium inwardly-rectifying channel, subfamily J, member 8 (kcnj8) antibody
  • potassium inwardly-rectifying channel, subfamily J, member 8 (Kcnj8) antibody
  • AI448900 antibody
  • gnite antibody
  • Kir6.1 antibody
  • si:dkey-183c2.2 antibody
  • slmbr antibody
  • sltr antibody
  • uKATP-1 antibody
  • UKATP1 antibody
  • zkir6.1 antibody

Protein level used designations for KCNJ8

potassium inwardly-rectifying channel, subfamily J, member 8 , Kir 6.1 , potassium inwardly-rectifying channel J8 , ATP-sensitive inward rectifier potassium channel 8 , inward rectifier K(+) channel Kir6.1 , inwardly rectifying potassium channel KIR6.1 , potassium channel, inwardly rectifying subfamily J member 8 , inwardly rectifier K(+) channel Kir6.1 , uKATP-1 , Inwardly rectifying potassium channel gene subfamily J-8 (ATP sensitive) , Inwardly rectifying potassium channel gene, subfamily J-8 (ATP sensitive) , Kir6.1 like

GENE ID SPECIES
706369 Macaca mulatta
740604 Pan troglodytes
100010504 Monodelphis domestica
100124909 Xenopus (Silurana) tropicalis
3764 Homo sapiens
16523 Mus musculus
25472 Rattus norvegicus
561090 Danio rerio
100526745 Xenopus laevis
486639 Canis lupus familiaris
100152631 Sus scrofa
282572 Bos taurus
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