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anti-Potassium Large Conductance Calcium-Activated Channel, Subfamily M, alpha Member 1 (KCNMA1) Antibodies

MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. Additionally we are shipping KCNMA1 Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
KCNMA1 3778 Q12791
KCNMA1 16531 Q08460
KCNMA1 83731 Q62976
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Top anti-KCNMA1 Antibodies at antibodies-online.com

Showing 10 out of 66 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-KCNMA1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Hela cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Chicken Rabbit Un-conjugated IHC, WB Immunohistochemistry with Prostate tissue at an antibody concentration of 5µg/ml using anti-KCNMA1 antibody (ARP35092_P050) 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), WB Anti- KCNMA1antibody,IHC(P) IHC(P): Mouse Intestine Tissue Anti- KCNMA1antibody,IHC(P) IHC(P): Human Lung Cancer Tissue 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Mouse Un-conjugated IHC (fro), IF, IP, WB Immunohistochemistry analysis of Slo using AM20106PU-N tested on Mouse cerebellum tissues. Nuclear staining of oligodendrocytes and microglial cells of the white matter. Neurons are negative. Western blot analysis of Slo1 on rat brain membrane tissues using a 1/1000 dilution of AM20106PU-N 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated IHC (p) Immunohistochemistry analyzes of MaxiKα antibody in paraffin-embedded human brain tissue. Western blot (WB) analysis of MaxiKα antibody in extracts from HeLa cells. 0.1 mg Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC (p) Anti-KCNMA1 antibody  ABIN1048989 IHC staining of human breast, vessel. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated IHC (p), WB Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated WB Western blot analysis of KCNMA1 expression in Caski (A), rat brain (B) whole cell lysates. 200 μL Log in to see 9 Days
$487.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated IHC (p), WB Anti-KCNMA1 antibody IHC staining of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN958995 concentration 5 ug/ml. 50 μg Log in to see 8 to 10 Days
$676.50
Details

KCNMA1 Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-KCNMA1 Antibodies

  1. Chicken Polyclonal KCNMA1 Primary Antibody for WB - ABIN2780204 : Cambien, Rezzonico, Vitale, Rouzaire-Dubois, Dubois, Barthel, Karimdjee, Soilihi, Mograbi, Schmid-Alliana, Schmid-Antomarchi: Silencing of hSlo potassium channels in human osteosarcoma cells promotes tumorigenesis. in International journal of cancer. Journal international du cancer 2008 (PubMed)

More Antibodies against KCNMA1 Interaction Partners

Rabbit Potassium Large Conductance Calcium-Activated Channel, Subfamily M, alpha Member 1 (KCNMA1) interaction partners

  1. High cholesterol can reduce the protein expression of BK channel beta1 subunit in rabbit Oddi's sphincter (SO) cells which suggests high cholesterol can affect the function of BKca channel [BK channel beta1 subunit]

  2. Aldosterone does not contribute to the regulation of BK channel expression/activity in response to dietary K(+) loading.

Human Potassium Large Conductance Calcium-Activated Channel, Subfamily M, alpha Member 1 (KCNMA1) interaction partners

  1. Results indicate that silencing BKCa (KCa1.1) inhibits cell mobility, while silencing IKir (Kir2.1 (show KCNJ2 Antibodies)) increases cell mobility in human cardiac c-kit (show KIT Antibodies)+ progenitor cells.

  2. Suggest that BK channel modulation by auxiliary gamma subunits depends on intra- and/or juxta-membrane mechanisms.

  3. Suberoylanilide hydroxamic acid enhanced the expression of malignant genes such as KCNMA1 in lung cancer cells remaining after treatment, creating a more drug-resistant state.

  4. We conclude that arachidonic acid itself selectively activates the beta1-associated BKCa channel, destabilizing its closed state probably by interacting with the beta1-subunit, without modifying the channel voltage sensitivity

  5. The present study revealed that 11,12-EET targets the TRPV4 (show TRPV4 Antibodies)-TRPC1 (show TRPC1 Antibodies)-KCa1.1 complex to induce smooth muscle cell hyperpolarization and vascular relaxation in human LIMAs.

  6. DS-201 selectively targets the pore-forming alpha subunit (show POLG Antibodies) of human BKCa channels, thus enhancing the channel activities and increasing the subunit expression and trafficking.

  7. show that Slo1 is localized to the sperm flagellum and is inhibited by progesterone. Inhibition of hKSper by progesterone may depolarize the spermatozoon to open the calcium channel CatSper (show CATSPER1 Antibodies)

  8. our results strongly suggest that AT1R regulates BK channels through a close protein-protein interaction involving multiple BK regions and independent of G-protein activation.

  9. hSlo1c associates with Cav-1 (show CAV1 Antibodies) in human brain microvascular endothelial cells.A 57-amino acid (966-1022) fragment in hSlo1c was identified to be critical for hSlo1c/Cav-1 (show CAV1 Antibodies) interaction.

  10. Recombinant martentoxin selectively blocks KCNMA1/KCNMB4 (show KCNMB4 Antibodies) channels.

Mouse (Murine) Potassium Large Conductance Calcium-Activated Channel, Subfamily M, alpha Member 1 (KCNMA1) interaction partners

  1. This study demonstrated that The interaction of MaxiK channel with GAT3 (show SLC6A13 Antibodies) opens the possibility of a role of MaxiK channel in GABA homeostasis and signaling.

  2. the enhanced effect of amiloride on potassium secretion in wild-type compared to knockout mice on the alkaline diet clarify a BK- alpha/beta4-mediated potassium secretory pathway in intercalated cells driven by ENaC (show SCNN1A Antibodies)-mediated sodium reabsorption

  3. Data suggest that the ion channels CaV1.3 (show CACNA1D Antibodies), bestrophin-1 (show BEST1 Antibodies) and maxiK were identified as players in the regulation of photoreceptor outer segments (POS) phagocytosis by the retinal pigment epithelium (RPE (show RPE Antibodies)).

  4. Data show that angiotensin II (Ang II) inhibited the current amplitude of Ca(2 (show CA2 Antibodies)+)-activated K(+) channels (BKCa) channel and decreased the slope of I-V curve.

  5. Suggest a negative feedback mechanism of the myogenic response in which CaV3.2 (show CACNA1H Antibodies) channel modulates downstream ryanodine receptor (show RYR3 Antibodies)-BKCa to hyperpolarize and relax arteries.

  6. AMPK (show PRKAA1 Antibodies) directly relaxes vascular smooth muscle cell by a decrease of [Ca(2 (show CA2 Antibodies)+)]i. This is achieved by calcium sequestration via SERCA (show ATP2A3 Antibodies) activation, as well as activation of BKCa channels.

  7. Tracheal smooth muscle relaxation induced by hydrogen sulfide (show SQRDL Antibodies) was regulated by activating BKCa.

  8. BKCa channels expressed in sensory neurons exert inhibitory control on sensory input in inflammatory pain states.

  9. BK(-/-) RPE (show RPE Antibodies) in vivo retained phagocytic capability but this activity, which is normally well synchronized with circadian photoreceptor shedding, shifted out of phase.

  10. along with Ca(2 (show CA2 Antibodies)+) and voltage, PIP2 is a third factor critical to the integral control of BK channel activity

Cow (Bovine) Potassium Large Conductance Calcium-Activated Channel, Subfamily M, alpha Member 1 (KCNMA1) interaction partners

  1. analysis of SLO3 (show KCNU1 Antibodies) K+ channels shows evolutionary divergence for an RCK1 region of critical function

Xenopus laevis Potassium Large Conductance Calcium-Activated Channel, Subfamily M, alpha Member 1 (KCNMA1) interaction partners

  1. A neural-specific splice-variant exon of Slo serves as a gain-of-function module and allows physiologically relevant levels of membrane potential and intracellular calcium to activate the resultant channel effectively during Xenopus embryogenesis.

Pig (Porcine) Potassium Large Conductance Calcium-Activated Channel, Subfamily M, alpha Member 1 (KCNMA1) interaction partners

  1. Porcine K2P3.1 (show KCNK3 Antibodies) channels exhibit atrial expression and functional properties similar to their human orthologs, supporting a general role as antiarrhythmic drug targets.

  2. Inositol trisphosphate is an activator of BKCA channels in porcine coronary smooth muscle cells and exerts a coronary artery-relaxing effect.

  3. Testerone-induced relaxation of endothelium-denuded coronary arteries is mediated, at least in part, by enhanced NO production, leading to cGMP synthesis and PKG (show PRKG1 Antibodies) activation, which, in turn, opens BK(Ca) channels.

KCNMA1 Antigen Profile

Protein Summary

MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit, which is the product of this gene, and the modulatory beta subunit. Intracellular calcium regulates the physical association between the alpha and beta subunits. Alternatively spliced transcript variants encoding different isoforms have been identified.

Gene names and symbols associated with KCNMA1

  • calcium-activated BK potassium channel, alpha subunit (kcnma1) antibody
  • potassium large conductance calcium-activated channel, subfamily M, alpha member 1 (kcnma1) antibody
  • potassium large conductance calcium-activated channel, subfamily M, alpha member 1 (KCNMA1) antibody
  • maxi-K channel alpha subunit (RBSLO1) antibody
  • potassium large conductance calcium-activated channel, subfamily M, alpha member 1 (Kcnma1) antibody
  • potassium large conductance calcium-activated channel, subfamily M, alpha member 1a (kcnma1a) antibody
  • 5730414M22Rik antibody
  • bA205K10.1 antibody
  • BKCa antibody
  • bktm antibody
  • cSlo antibody
  • DDBDRAFT_0190653 antibody
  • DDBDRAFT_0235401 antibody
  • DDB_0190653 antibody
  • DDB_0235401 antibody
  • KCa1.1 antibody
  • Kcnma antibody
  • kcnma1 antibody
  • kcnma1-A antibody
  • KCNMA1b antibody
  • KCNMA1c antibody
  • MaxiK antibody
  • mSlo antibody
  • mSlo1 antibody
  • sakca antibody
  • si:ch211-39f22.2 antibody
  • Slo antibody
  • SLO-ALPHA antibody
  • slo1 antibody

Protein level used designations for KCNMA1

calcium-activated potassium channel subunit alpha 1 , potassium large conductance calcium-activated channel, subfamily M, alpha member 1 , pulmonary calcium activated potassium channel , calcium-activated potassium channel subunit alpha-1-like , BK channel , BKCA alpha , KCa1.1 , calcium-activated potassium channel subunit alpha-1 , calcium-activated potassium channel, subfamily M subunit alpha-1 , k(VCA)alpha , large conductance calcium-activated potassium channel alpha subunit , maxi K channel , maxiK , rbSlo , slo homolog , slo-alpha , slo1 , slowpoke homolog , BK channel alpha subunit , BKCA alpha subunit , hSlo , maxi-K channel HSLO , stretch-activated Kca channel , calcium-activated potassium channel alpha subunit , bSlo , xSlo , MaxiK calcium-activated potassium channel , calcium activated potassium channel protein , large conductance calcium-activated potassium channel subfamily M alpha member 1 , large conductance calcium-activated potassium (BK) channel alpha subunit a , slo1a

GENE ID SPECIES
8617340 Dictyostelium discoideum AX4
100008593 Danio rerio
100270685 Ovis aries
100454095 Pongo abelii
100008745 Oryctolagus cuniculus
3778 Homo sapiens
16531 Mus musculus
83731 Rattus norvegicus
282573 Bos taurus
373712 Xenopus laevis
374065 Gallus gallus
403984 Canis lupus familiaris
397434 Sus scrofa
574103 Macaca mulatta
568554 Danio rerio
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