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Potassium Large Conductance Calcium-Activated Channel, Subfamily M, alpha Member 1 (KCNMA1) ELISA Kits

MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. Additionally we are shipping KCNMA1 Antibodies (66) and KCNMA1 Proteins (5) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human KCNMA1 KCNMA1 3778 Q12791
Anti-Mouse KCNMA1 KCNMA1 16531 Q08460
Anti-Rat KCNMA1 KCNMA1 83731 Q62976
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More ELISA Kits for KCNMA1 Interaction Partners

Rabbit Potassium Large Conductance Calcium-Activated Channel, Subfamily M, alpha Member 1 (KCNMA1) interaction partners

  1. High cholesterol can reduce the protein expression of BK channel beta1 subunit in rabbit Oddi's sphincter (SO) cells which suggests high cholesterol can affect the function of BKca channel [BK channel beta1 subunit]

  2. Aldosterone does not contribute to the regulation of BK channel expression/activity in response to dietary K(+) loading.

Human Potassium Large Conductance Calcium-Activated Channel, Subfamily M, alpha Member 1 (KCNMA1) interaction partners

  1. Results indicate that silencing BKCa (KCa1.1) inhibits cell mobility, while silencing IKir (Kir2.1 (show KCNJ2 ELISA Kits)) increases cell mobility in human cardiac c-kit (show KIT ELISA Kits)+ progenitor cells.

  2. Suggest that BK channel modulation by auxiliary gamma subunits depends on intra- and/or juxta-membrane mechanisms.

  3. Suberoylanilide hydroxamic acid enhanced the expression of malignant genes such as KCNMA1 in lung cancer cells remaining after treatment, creating a more drug-resistant state.

  4. We conclude that arachidonic acid itself selectively activates the beta1-associated BKCa channel, destabilizing its closed state probably by interacting with the beta1-subunit, without modifying the channel voltage sensitivity

  5. The present study revealed that 11,12-EET targets the TRPV4 (show TRPV4 ELISA Kits)-TRPC1 (show TRPC1 ELISA Kits)-KCa1.1 complex to induce smooth muscle cell hyperpolarization and vascular relaxation in human LIMAs.

  6. DS-201 selectively targets the pore-forming alpha subunit (show POLG ELISA Kits) of human BKCa channels, thus enhancing the channel activities and increasing the subunit expression and trafficking.

  7. show that Slo1 is localized to the sperm flagellum and is inhibited by progesterone. Inhibition of hKSper by progesterone may depolarize the spermatozoon to open the calcium channel CatSper (show CATSPER1 ELISA Kits)

  8. our results strongly suggest that AT1R regulates BK channels through a close protein-protein interaction involving multiple BK regions and independent of G-protein activation.

  9. hSlo1c associates with Cav-1 (show CAV1 ELISA Kits) in human brain microvascular endothelial cells.A 57-amino acid (966-1022) fragment in hSlo1c was identified to be critical for hSlo1c/Cav-1 (show CAV1 ELISA Kits) interaction.

  10. Recombinant martentoxin selectively blocks KCNMA1/KCNMB4 (show KCNMB4 ELISA Kits) channels.

Mouse (Murine) Potassium Large Conductance Calcium-Activated Channel, Subfamily M, alpha Member 1 (KCNMA1) interaction partners

  1. the enhanced effect of amiloride on potassium secretion in wild-type compared to knockout mice on the alkaline diet clarify a BK- alpha/beta4-mediated potassium secretory pathway in intercalated cells driven by ENaC (show SCNN1A ELISA Kits)-mediated sodium reabsorption

  2. Data suggest that the ion channels CaV1.3, bestrophin-1 and maxiK were identified as players in the regulation of photoreceptor outer segments (POS) phagocytosis by the retinal pigment epithelium (RPE).

  3. Data show that angiotensin II (Ang II) inhibited the current amplitude of Ca(2 (show CA2 ELISA Kits)+)-activated K(+) channels (BKCa) channel and decreased the slope of I-V curve.

  4. Suggest a negative feedback mechanism of the myogenic response in which CaV3.2 (show CACNA1H ELISA Kits) channel modulates downstream ryanodine receptor (show RYR3 ELISA Kits)-BKCa to hyperpolarize and relax arteries.

  5. AMPK (show PRKAA1 ELISA Kits) directly relaxes vascular smooth muscle cell by a decrease of [Ca(2 (show CA2 ELISA Kits)+)]i. This is achieved by calcium sequestration via SERCA (show ATP2A3 ELISA Kits) activation, as well as activation of BKCa channels.

  6. Tracheal smooth muscle relaxation induced by hydrogen sulfide was regulated by activating BKCa.

  7. BKCa channels expressed in sensory neurons exert inhibitory control on sensory input in inflammatory pain states.

  8. BK(-/-) RPE in vivo retained phagocytic capability but this activity, which is normally well synchronized with circadian photoreceptor shedding, shifted out of phase.

  9. along with Ca(2 (show CA2 ELISA Kits)+) and voltage, PIP2 is a third factor critical to the integral control of BK channel activity

  10. The nuclear BK channel ia a molecular link between neuronal activity and nuclear calcium signaling to convey signals from synapse to nucleus; it is a new modulator, operating at the nuclear envelope, of synaptic activity-dependent neuronal functions.

Cow (Bovine) Potassium Large Conductance Calcium-Activated Channel, Subfamily M, alpha Member 1 (KCNMA1) interaction partners

  1. analysis of SLO3 K+ channels shows evolutionary divergence for an RCK1 region of critical function

Xenopus laevis Potassium Large Conductance Calcium-Activated Channel, Subfamily M, alpha Member 1 (KCNMA1) interaction partners

  1. A neural-specific splice-variant exon of Slo serves as a gain-of-function module and allows physiologically relevant levels of membrane potential and intracellular calcium to activate the resultant channel effectively during Xenopus embryogenesis.

Pig (Porcine) Potassium Large Conductance Calcium-Activated Channel, Subfamily M, alpha Member 1 (KCNMA1) interaction partners

  1. Porcine K2P3.1 (show KCNK3 ELISA Kits) channels exhibit atrial expression and functional properties similar to their human orthologs, supporting a general role as antiarrhythmic drug targets.

  2. Inositol trisphosphate is an activator of BKCA channels in porcine coronary smooth muscle cells and exerts a coronary artery-relaxing effect.

  3. Testerone-induced relaxation of endothelium-denuded coronary arteries is mediated, at least in part, by enhanced NO production, leading to cGMP synthesis and PKG (show PRKG1 ELISA Kits) activation, which, in turn, opens BK(Ca) channels.

KCNMA1 Antigen Profile

Antigen Summary

MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit, which is the product of this gene, and the modulatory beta subunit. Intracellular calcium regulates the physical association between the alpha and beta subunits. Alternatively spliced transcript variants encoding different isoforms have been identified.

Gene names and symbols associated with KCNMA1

  • calcium-activated BK potassium channel, alpha subunit (kcnma1) antibody
  • potassium large conductance calcium-activated channel, subfamily M, alpha member 1 (kcnma1) antibody
  • potassium large conductance calcium-activated channel, subfamily M, alpha member 1 (KCNMA1) antibody
  • maxi-K channel alpha subunit (RBSLO1) antibody
  • potassium large conductance calcium-activated channel, subfamily M, alpha member 1 (Kcnma1) antibody
  • potassium large conductance calcium-activated channel, subfamily M, alpha member 1a (kcnma1a) antibody
  • 5730414M22Rik antibody
  • bA205K10.1 antibody
  • BKCa antibody
  • bktm antibody
  • cSlo antibody
  • DDBDRAFT_0190653 antibody
  • DDBDRAFT_0235401 antibody
  • DDB_0190653 antibody
  • DDB_0235401 antibody
  • KCa1.1 antibody
  • Kcnma antibody
  • kcnma1 antibody
  • kcnma1-A antibody
  • KCNMA1b antibody
  • KCNMA1c antibody
  • MaxiK antibody
  • mSlo antibody
  • mSlo1 antibody
  • sakca antibody
  • si:ch211-39f22.2 antibody
  • Slo antibody
  • SLO-ALPHA antibody
  • slo1 antibody

Protein level used designations for KCNMA1

calcium-activated potassium channel subunit alpha 1 , potassium large conductance calcium-activated channel, subfamily M, alpha member 1 , pulmonary calcium activated potassium channel , calcium-activated potassium channel subunit alpha-1-like , BK channel , BKCA alpha , KCa1.1 , calcium-activated potassium channel subunit alpha-1 , calcium-activated potassium channel, subfamily M subunit alpha-1 , k(VCA)alpha , large conductance calcium-activated potassium channel alpha subunit , maxi K channel , maxiK , rbSlo , slo homolog , slo-alpha , slo1 , slowpoke homolog , BK channel alpha subunit , BKCA alpha subunit , hSlo , maxi-K channel HSLO , stretch-activated Kca channel , calcium-activated potassium channel alpha subunit , bSlo , xSlo , MaxiK calcium-activated potassium channel , calcium activated potassium channel protein , large conductance calcium-activated potassium channel subfamily M alpha member 1 , large conductance calcium-activated potassium (BK) channel alpha subunit a , slo1a

GENE ID SPECIES
8617340 Dictyostelium discoideum AX4
100008593 Danio rerio
100270685 Ovis aries
100454095 Pongo abelii
100008745 Oryctolagus cuniculus
3778 Homo sapiens
16531 Mus musculus
83731 Rattus norvegicus
282573 Bos taurus
373712 Xenopus laevis
374065 Gallus gallus
403984 Canis lupus familiaris
397434 Sus scrofa
574103 Macaca mulatta
568554 Danio rerio
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