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anti-Potassium Large Conductance Calcium-Activated Channel, Subfamily M, beta Member 1 (KCNMB1) Antibodies

MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. Additionally we are shipping KCNMB1 Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
KCNMB1 16533 Q8CAE3
KCNMB1 3779 Q16558
KCNMB1 29747 P97678
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Top anti-KCNMB1 Antibodies at antibodies-online.com

Showing 10 out of 39 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of KCNMB1 Antibody (Center) in A549 cell line lysates (35ug/lane). This demonstrates the KCNMB1 antibody detected the KCNMB1 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB KCNMB1 Antibody (Center) (ABIN658607) western blot analysis in A549 cell line lysates (35 µg/lane). This demonstrates the KCNMB1 antibody detected the KCNMB1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB WB Image Sample (30 ug of whole cell lysate) A: A431 , B: H1299 12% SDS PAGE antibody diluted at 1:1000 WB Image Sample (50 ug of whole cell lysate) A: mouse heart 12% SDS PAGE antibody diluted at 1:10000 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Rabbit Un-conjugated IHC (p) Immunohistochemistry (IHC) analyzes of MaxiKbeta antibody in paraffin-embedded human brain tissue. 0.1 mg Log in to see 6 to 8 Days
$390.50
Details
Mouse Rabbit Un-conjugated ELISA   100 μg Log in to see 8 to 10 Days
$405.17
Details
Human Rabbit Alkaline Phosphatase (AP) ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated IHC, WB   100 μL Log in to see 7 to 8 Days
$454.67
Details
Human Rabbit Un-conjugated WB 400 μL Log in to see 6 Days
$457.14
Details
Human Rabbit Un-conjugated ELISA   200 μL Log in to see 8 to 10 Days
$713.17
Details
Human Rabbit Alexa Fluor 350 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details

KCNMB1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-KCNMB1 Antibodies

  1. Human Polyclonal KCNMB1 Primary Antibody for IHC, WB - ABIN350419 : Fernuandez-Fernuandez, Tomuas, Vuazquez, Orio, Latorre, Sentui, Marrugat, Valverde: Gain-of-function mutation in the KCNMB1 potassium channel subunit is associated with low prevalence of diastolic hypertension. in The Journal of clinical investigation 2004 (PubMed)
    Show all 5 references for ABIN350419

  2. Human Polyclonal KCNMB1 Primary Antibody for WB - ABIN658607 : Talmud, Drenos, Shah, Shah, Palmen, Verzilli, Gaunt, Pallas, Lovering, Li, Casas, Sofat, Kumari, Rodriguez, Johnson, Newhouse, Dominiczak, Samani, Caulfield, Sever, Stanton, Shields, Padmanabhan et al.: Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. ... in American journal of human genetics 2009 (PubMed)

More Antibodies against KCNMB1 Interaction Partners

Mouse (Murine) Potassium Large Conductance Calcium-Activated Channel, Subfamily M, beta Member 1 (KCNMB1) interaction partners

  1. 7-Ketocholesterol induces the reduction of KCNMB1 through the AhR pathway.

  2. BK channel (show KCNMA1 Antibodies) activity directly affects vascular tone but influences blood pressure independent of this effect via different pathways

  3. up-regulation of NF-kappaB (show NFKB1 Antibodies)-dependent MuRF1 (show TRIM63 Antibodies) expression is a novel mechanism that leads to BK channelopathy and vasculopathy in diabetes

  4. Our results support a model whereby subcellular anchoring of CaN by AKAP150 (show AKAP5 Antibodies) is a key molecular determinant of vascular BKCa (show KCNMA1 Antibodies) channel remodeling, which contributes to vasoconstriction during diabetes mellitus.

  5. The activity of BKbeta1 is higher in cerebral smooth muscle cells compared to pulmonary artery.

  6. BK channels play a prominent role in smooth muscle function only in the distal colon of mice. Defects in smooth muscle BK channel (show KCNMA1 Antibodies) function disrupt colonic motility causing constipation.

  7. Impaired sodium excretion resulting form loss of normal purinergic regulation of ENaC (show SCNN1A Antibodies) in BK-beta4 null mice likely contributes to their elevated blood pressure

  8. these results suggested that oxidative stress inhibited Akt (show AKT1 Antibodies) signaling and facilitated the FOXO (show FOXO3 Antibodies)-3a/FBXO-dependent BK-beta(1) degradation in diabetic vessels.

  9. Reduced vascular BK channel (show KCNMA1 Antibodies) function does not protect against hypotension in the early stage of septic shock; in the later stage, smooth muscle BK channel (show KCNMA1 Antibodies) deficiency enhances organ damage and mortality

  10. BKbeta4 (show KCNMB4 Antibodies) and to a lesser degree BKbeta1 transcripts and protein are detected in several astrocytic populations and cultured cells.

Human Potassium Large Conductance Calcium-Activated Channel, Subfamily M, beta Member 1 (KCNMB1) interaction partners

  1. The study demonstrates that both transmembrane domains of BKbeta1 are required to provide the characteristic ion current phenotype of beta1-containing BK channels.

  2. Data show that two lysine residues that are unique to the N terminus of calcium-activated potassium channel subunit beta-1 were identified to be sufficient for voltage-sensor modulation.

  3. To determine the relationship between atherosclerosis and KCNMB1, we studied some atherogenic factors affecting vascular tone. Blood of atherosclerotic patients shows increased concentration of 7-ketocholesterol, possibly a harmful lipid to blood vessels.

  4. N-terminal isoforms of the large-conductance Ca(2 (show CA2 Antibodies))-activated K channel (show KCNC4 Antibodies) are differentially modulated by the auxiliary beta1-subunit.

  5. HIF-1alpha (show HIF1A Antibodies) increases KCNMB1 expression in response to hypoxia in human pulmonary artery smooth muscle cells by binding to two hypoxia response elements located at -3,540 to -3,311 of the KCNMB1 promoter

  6. Here we found that KCNMB1 common variant Glu65Lys influences glomerular filtration rate across multiple populations of different clinical characteristics and biogeographic ancestries.

  7. downregulation of vascular BK-beta(1) expression in diabetes and in high-glucose culture conditions was associated with FOXO (show FOXO3 Antibodies)-3a/FBXO-dependent increase in BK-beta(1) degradation.

  8. The expressed hSloalpha + beta1 subunit complex demonstrated to be fully functional for its typical single-channel traces, Ca(2 (show CA2 Antibodies)+)-sensitivity, voltage-dependency, high conductance (151 +/- 7 pS), and its pharmacological activation and inhibition.

  9. Results reveal the first ion channel subunit as a direct target of SRF-MYOCD (show MYOCD Antibodies) transactivation, providing further insight into the role of MYOCD (show MYOCD Antibodies) as a master regulator of the SMC (show DYM Antibodies) contractile phenotype.

  10. Phosphorylation-dependent functional coupling of hSlo (show KCNMA1 Antibodies) and its hbeta 4 subunit

Pig (Porcine) Potassium Large Conductance Calcium-Activated Channel, Subfamily M, beta Member 1 (KCNMB1) interaction partners

  1. The study verified that the BK(Ca) channel alpha-subunit (show POLG Antibodies) is located to smooth muscle cells of porcine basilar and middle cerebral arteries.

KCNMB1 Antigen Profile

Protein Summary

MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the product of this gene, the modulatory beta subunit. Intracellular calcium regulates the physical association between the alpha and beta subunits.

Gene names and symbols associated with KCNMB1

  • potassium large conductance calcium-activated channel, subfamily M, beta member 1 (KCNMB1) antibody
  • potassium large conductance calcium-activated channel, subfamily M, beta member 1 (Kcnmb1) antibody
  • BKBETA antibody
  • BKbeta1 antibody
  • hbeta1 antibody
  • hslo-beta antibody
  • K(VCA)beta antibody
  • k(VCA)beta-1 antibody
  • KCNMB1 antibody
  • SLO-BETA antibody
  • slo-beta-1 antibody

Protein level used designations for KCNMB1

calcium-activated potassium channel subunit beta-1 , calcium-activated potassium channel beta subunit , potassium large conductance calcium-activated channel, subfamily M, beta member 1 , BK channel beta subunit , BK channel subunit beta-1 , BKbeta , calcium-activated potassium channel subunit beta , calcium-activated potassium channel, subfamily M subunit beta-1 , charybdotoxin receptor subunit beta-1 , k(VCA)beta-1 , maxi K channel subunit beta-1 , slo-beta , slo-beta-1 , large conductance Ca2+-activated K+ channel beta 1 subunit , BKbeta1 , slowpoke-beta , calcium activated potassium channel beta subunit , calcium activated potassium channel beta subunit protein , calcium dependent potassium channel beta subunit protein , large conductance Ca2+-activated K+ channel beta1 subunit , large conductance calcium-activated potassium channel beta subunit , large conductance calcium-activated potassium channel beta1 subunit , maxi-K channel beta subunit

GENE ID SPECIES
395301 Gallus gallus
462258 Pan troglodytes
16533 Mus musculus
3779 Homo sapiens
29747 Rattus norvegicus
407176 Bos taurus
403983 Canis lupus familiaris
100009034 Oryctolagus cuniculus
100271876 Sus scrofa
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