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Potassium Large Conductance Calcium-Activated Channel, Subfamily M, beta Member 1 (KCNMB1) ELISA Kits

MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. Additionally we are shipping KCNMB1 Antibodies (39) and KCNMB1 Proteins (5) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Mouse KCNMB1 KCNMB1 16533 Q8CAE3
Anti-Human KCNMB1 KCNMB1 3779 Q16558
Anti-Rat KCNMB1 KCNMB1 29747 P97678
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More ELISA Kits for KCNMB1 Interaction Partners

Mouse (Murine) Potassium Large Conductance Calcium-Activated Channel, Subfamily M, beta Member 1 (KCNMB1) interaction partners

  1. 7-Ketocholesterol induces the reduction of KCNMB1 through the AhR pathway.

  2. BK channel (show KCNMA1 ELISA Kits) activity directly affects vascular tone but influences blood pressure independent of this effect via different pathways

  3. up-regulation of NF-kappaB (show NFKB1 ELISA Kits)-dependent MuRF1 (show TRIM63 ELISA Kits) expression is a novel mechanism that leads to BK channelopathy and vasculopathy in diabetes

  4. Our results support a model whereby subcellular anchoring of CaN by AKAP150 (show AKAP5 ELISA Kits) is a key molecular determinant of vascular BKCa (show KCNMA1 ELISA Kits) channel remodeling, which contributes to vasoconstriction during diabetes mellitus.

  5. The activity of BKbeta1 is higher in cerebral smooth muscle cells compared to pulmonary artery.

  6. BK channels play a prominent role in smooth muscle function only in the distal colon of mice. Defects in smooth muscle BK channel (show KCNMA1 ELISA Kits) function disrupt colonic motility causing constipation.

  7. Impaired sodium excretion resulting form loss of normal purinergic regulation of ENaC (show SCNN1A ELISA Kits) in BK-beta4 null mice likely contributes to their elevated blood pressure

  8. these results suggested that oxidative stress inhibited Akt (show AKT1 ELISA Kits) signaling and facilitated the FOXO (show FOXO3 ELISA Kits)-3a/FBXO-dependent BK-beta(1) degradation in diabetic vessels.

  9. Reduced vascular BK channel (show KCNMA1 ELISA Kits) function does not protect against hypotension in the early stage of septic shock; in the later stage, smooth muscle BK channel (show KCNMA1 ELISA Kits) deficiency enhances organ damage and mortality

  10. BKbeta4 (show KCNMB4 ELISA Kits) and to a lesser degree BKbeta1 transcripts and protein are detected in several astrocytic populations and cultured cells.

Human Potassium Large Conductance Calcium-Activated Channel, Subfamily M, beta Member 1 (KCNMB1) interaction partners

  1. The study demonstrates that both transmembrane domains of BKbeta1 are required to provide the characteristic ion current phenotype of beta1-containing BK channels.

  2. Data show that two lysine residues that are unique to the N terminus of calcium-activated potassium channel subunit beta-1 were identified to be sufficient for voltage-sensor modulation.

  3. To determine the relationship between atherosclerosis and KCNMB1, we studied some atherogenic factors affecting vascular tone. Blood of atherosclerotic patients shows increased concentration of 7-ketocholesterol, possibly a harmful lipid to blood vessels.

  4. N-terminal isoforms of the large-conductance Ca(2 (show CA2 ELISA Kits))-activated K channel (show KCNC4 ELISA Kits) are differentially modulated by the auxiliary beta1-subunit.

  5. HIF-1alpha (show HIF1A ELISA Kits) increases KCNMB1 expression in response to hypoxia in human pulmonary artery smooth muscle cells by binding to two hypoxia response elements located at -3,540 to -3,311 of the KCNMB1 promoter

  6. Here we found that KCNMB1 common variant Glu65Lys influences glomerular filtration rate across multiple populations of different clinical characteristics and biogeographic ancestries.

  7. downregulation of vascular BK-beta(1) expression in diabetes and in high-glucose culture conditions was associated with FOXO (show FOXO3 ELISA Kits)-3a/FBXO-dependent increase in BK-beta(1) degradation.

  8. The expressed hSloalpha + beta1 subunit complex demonstrated to be fully functional for its typical single-channel traces, Ca(2 (show CA2 ELISA Kits)+)-sensitivity, voltage-dependency, high conductance (151 +/- 7 pS), and its pharmacological activation and inhibition.

  9. Results reveal the first ion channel subunit as a direct target of SRF-MYOCD (show MYOCD ELISA Kits) transactivation, providing further insight into the role of MYOCD (show MYOCD ELISA Kits) as a master regulator of the SMC (show DYM ELISA Kits) contractile phenotype.

  10. Phosphorylation-dependent functional coupling of hSlo (show KCNMA1 ELISA Kits) and its hbeta 4 subunit

Pig (Porcine) Potassium Large Conductance Calcium-Activated Channel, Subfamily M, beta Member 1 (KCNMB1) interaction partners

  1. The study verified that the BK(Ca) channel alpha-subunit (show POLG ELISA Kits) is located to smooth muscle cells of porcine basilar and middle cerebral arteries.

KCNMB1 Antigen Profile

Antigen Summary

MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the product of this gene, the modulatory beta subunit. Intracellular calcium regulates the physical association between the alpha and beta subunits.

Gene names and symbols associated with KCNMB1

  • potassium large conductance calcium-activated channel, subfamily M, beta member 1 (KCNMB1) antibody
  • potassium large conductance calcium-activated channel, subfamily M, beta member 1 (Kcnmb1) antibody
  • BKBETA antibody
  • BKbeta1 antibody
  • hbeta1 antibody
  • hslo-beta antibody
  • K(VCA)beta antibody
  • k(VCA)beta-1 antibody
  • KCNMB1 antibody
  • SLO-BETA antibody
  • slo-beta-1 antibody

Protein level used designations for KCNMB1

calcium-activated potassium channel subunit beta-1 , calcium-activated potassium channel beta subunit , potassium large conductance calcium-activated channel, subfamily M, beta member 1 , BK channel beta subunit , BK channel subunit beta-1 , BKbeta , calcium-activated potassium channel subunit beta , calcium-activated potassium channel, subfamily M subunit beta-1 , charybdotoxin receptor subunit beta-1 , k(VCA)beta-1 , maxi K channel subunit beta-1 , slo-beta , slo-beta-1 , large conductance Ca2+-activated K+ channel beta 1 subunit , BKbeta1 , slowpoke-beta , calcium activated potassium channel beta subunit , calcium activated potassium channel beta subunit protein , calcium dependent potassium channel beta subunit protein , large conductance Ca2+-activated K+ channel beta1 subunit , large conductance calcium-activated potassium channel beta subunit , large conductance calcium-activated potassium channel beta1 subunit , maxi-K channel beta subunit

GENE ID SPECIES
395301 Gallus gallus
462258 Pan troglodytes
16533 Mus musculus
3779 Homo sapiens
29747 Rattus norvegicus
407176 Bos taurus
403983 Canis lupus familiaris
100009034 Oryctolagus cuniculus
100271876 Sus scrofa
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